TNNI3 Gene Cardiomyopathy, familial hypertrophic type 7 NGS Genetic Test
Short Name: TNNI3 Gene Test
Also known as: TNNI3 Gene Mutation Test, Hypertrophic Cardiomyopathy Type 7 Genetic Test, Familial HCM Type 7 NGS Test
TNNI3 Gene Cardiomyopathy, familial hypertrophic type 7 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS (Next-Generation Sequencing) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the TNNI3 Gene Cardiomyopathy NGS Genetic Test is to detect mutations in the TNNI3 gene associated with familial hypertrophic cardiomyopathy type 7. This test aids in confirming diagnosis, assessing risk for family members, guiding treatment decisions, and enabling genetic counseling for affected individuals and their families.
- Test Code
- 5232
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- NGS (Next-Generation Sequencing)
Sample Collection
No specific preparation is required. Ensure genetic counseling is completed and a pedigree chart is drawn if applicable.
Method: Venipuncture or blood drop
Laboratory Analysis
A blood sample will be collected via venipuncture or a blood drop on an FTA card by a trained phlebotomist.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Store the sample as instructed and await report delivery in 3-4 weeks.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the TNNI3 Gene Cardiomyopathy NGS Genetic Test is to detect mutations in the TNNI3 gene associated with familial hypertrophic cardiomyopathy type 7. This test aids in confirming diagnosis, assessing risk for family members, guiding treatment decisions, and enabling genetic counseling for affected individuals and their families.
How to Prepare
- Fast for 8-12 hours if specified, though not typically required
- Avoid strenuous activity before sample collection
- Bring identification and test requisition form
- Inform the collector of any medications or recent transfusions
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for TNNI3 mutations is essential for early detection and management of familial hypertrophic cardiomyopathy, especially in families with a history of cardiac disorders."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Incorrect labeling or missing documentation
- Contaminated or degraded sample
Understanding Your Results
Positive for pathogenic variant
Confirms genetic diagnosis of TNNI3-related cardiomyopathy; recommend cardiac evaluation and family screening.
Action: Consult a cardiologist and genetic counselor for management.
Negative for pathogenic variant
No known mutations detected; does not rule out other genetic or non-genetic causes.
Action: Continue clinical monitoring if symptoms persist.
Variant of uncertain significance (VUS)
Genetic change found but clinical significance unknown; requires further study.
Action: Follow up with genetic counseling and periodic re-evaluation.
Consult a doctor if you experience symptoms like chest pain, shortness of breath, or fainting, have a family history of cardiomyopathy, or receive a positive genetic test result. Immediate medical attention is needed for severe symptoms such as sudden dizziness or heart palpitations.
Limitations
- ⚠May not detect all possible genetic variants or mutations
- ⚠Results require interpretation by a genetic specialist
- ⚠Does not replace clinical diagnosis; must be correlated with symptoms and other tests
- ⚠Limited to known pathogenic variants in the TNNI3 gene
Risks & Considerations
- ●Minor bruising or pain at the puncture site
- ●Rare risk of infection or hematoma
- ●Psychological impact of genetic results; counseling recommended
Interfering Factors
- ●Sample contamination during collection or transport
- ●Improper storage of blood or DNA samples
- ●Use of anticoagulants that may affect DNA quality
- ●Recent blood transfusions potentially altering genetic material
Frequently Asked Questions
What is TNNI3 gene cardiomyopathy?
What are the symptoms of TNNI3 gene cardiomyopathy?
How is TNNI3 gene cardiomyopathy diagnosed?
What is the cost of the TNNI3 Gene Cardiomyopathy NGS Genetic Test in India?
Is home sample collection available for this test?
How long does it take to get the test results?
What sample type is required for the test?
Is fasting required before the test?
Who should consider getting this genetic test?
What does a positive test result mean?
Can this test detect all mutations related to cardiomyopathy?
Is genetic counseling recommended before and after the test?
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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