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TNNT2 Gene Cardiomyopathy, dilated type 1D NGS Genetic Test

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TNNT2 Gene Cardiomyopathy, dilated type 1D NGS Genetic Test

Short Name: TNNT2 Gene Test

Also known as: Dilated Cardiomyopathy 1D Genetic Test, TNNT2 Gene Mutation Test

TNNT2 Gene Cardiomyopathy, dilated type 1D NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To identify mutations in the TNNT2 gene that cause dilated cardiomyopathy type 1D, aiding in diagnosis, prognosis, and family risk assessment.

Test Code
5204
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No special preparation required. Genetic counseling is recommended to discuss test implications.

Method: Venipuncture for blood sample

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in the arm using standard venipuncture techniques.

Step 3

Report Delivery

Apply pressure to the puncture site with a cotton ball to prevent bleeding and bruising.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling to discuss test purpose, implications, and family history.
2
During the Test:Blood sample collection via venipuncture; procedure takes about 10-15 minutes.
3
After the Test:Resume normal activities; monitor puncture site for any signs of infection.

About This Test

Who Should Get This Test

To identify mutations in the TNNT2 gene that cause dilated cardiomyopathy type 1D, aiding in diagnosis, prognosis, and family risk assessment.

How to Prepare

  • Ensure proper patient identification
  • Use sterile collection equipment
  • Label samples accurately with patient details
  • Transport samples at room temperature unless specified

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Genetic testing for TNNT2 mutations is crucial for early detection and personalized treatment of dilated cardiomyopathy, especially in families with a history of heart disease."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
ContainerEDTA tube or FTA card
Collection MethodVenipuncture for blood sample

Sample Stability

Blood samples stable for 48 hours at room temperature
Extracted DNA stable for several months when stored properly
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient sample volume
  • Incorrect sample labeling

Understanding Your Results

Results indicate the presence or absence of mutations in the TNNT2 gene, which are associated with dilated cardiomyopathy type 1D.
Positive result: Pathogenic variant detected, indicating genetic predisposition to dilated cardiomyopathy; clinical evaluation and family screening recommended.
Negative result: No pathogenic variant detected; however, clinical symptoms may require further cardiac evaluation.
Variant of uncertain significance (VUS): Genetic change identified but not conclusively linked to disease; periodic re-evaluation advised.
⚠️ When to Consult a Doctor:

Consult a cardiologist or genetic specialist if you have a family history of heart disease, experience symptoms like shortness of breath, fatigue, or chest pain, or receive a positive genetic test result.

Limitations

  • ⚠May not detect all genetic variants or deep intronic mutations
  • ⚠Results require clinical correlation and genetic counseling
  • ⚠Cannot predict disease severity or onset age

Risks & Considerations

  • ●Minimal risks from blood draw, such as bruising, pain, or infection at the puncture site
  • ●Psychological impact of genetic results; counseling available

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA sample
  • ●Hemolyzed blood sample

Frequently Asked Questions

What is the TNNT2 Gene Cardiomyopathy Test?
It is a genetic test that uses next-generation sequencing to detect mutations in the TNNT2 gene, which are linked to dilated cardiomyopathy type 1D.
Who should consider taking this test?
Individuals with a family history of dilated cardiomyopathy, those experiencing symptoms like shortness of breath or fatigue, or patients with unexplained heart failure.
What are the common symptoms of TNNT2 gene cardiomyopathy?
Symptoms include shortness of breath, fatigue, swelling in legs and ankles, chest pain, irregular heartbeat, and fainting or dizziness.
How is the test performed?
A blood sample is collected and analyzed using NGS technology to identify genetic variants in the TNNT2 gene.
What is the cost of the TNNT2 Gene Cardiomyopathy Test?
The test costs INR 20,000, which includes sample collection, analysis, and report generation.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection across many cities in India for online bookings.
How long does it take to get the test results?
Results are typically available within 3 to 4 weeks after sample collection.
What does a positive test result mean?
A positive result indicates a mutation in the TNNT2 gene, suggesting a genetic predisposition to dilated cardiomyopathy; further clinical evaluation is recommended.
Can this test be used for prenatal diagnosis?
It may be used in prenatal settings with genetic counseling, but typically it is recommended for diagnostic purposes in symptomatic individuals or families.
Is genetic counseling necessary before taking the test?
Yes, genetic counseling is advised to understand the test implications, interpret results, and discuss family planning or management strategies.
What are the risks associated with this genetic test?
Risks are minimal and mainly related to blood draw, such as bruising or infection; psychological impacts of results are also possible.
How accurate is the NGS technology used in this test?
NGS is highly accurate for detecting genetic variants, but accuracy depends on sample quality and bioinformatics analysis; results are validated by experts.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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