Typhoid DNA Detection Test
Short Name: Typhoid DNA PCR
Also known as: Typhoid PCR Test, Salmonella typhi DNA PCR, S. typhi PCR
Typhoid DNA Detection Test test available at DNA Labs India for ₹9,000. Uses Polymerase Chain Reaction (PCR) on Whole Blood samples. Results in Reports are available 10 days after the sample is received. Samples submitted by 11 am follow the same reporting schedule.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Kothari Ramesh Shantilal
Consultant Microbiologist · Reg: 27670
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect Salmonella typhi DNA in whole blood using PCR technology. It may support early and accurate diagnosis of typhoid/enteric fever, helping clinicians plan appropriate management.
- Test Code
- 3715
- ICD Code
- A01.0
- Price
- ₹9,000
- Sample Type
- Whole Blood
- Result Time
- Reports are available 10 days after the sample is received. Samples submitted by 11 am follow the same reporting schedule.
- Fasting Required
- No
- Method
- Polymerase Chain Reaction (PCR)
Sample Collection
No special preparation is required. Inform your treating doctor about any antibiotics or other medicines you are taking.
Method: Venipuncture by trained phlebotomist
Laboratory Analysis
A small sample of blood will be drawn from a vein in your arm using sterile, single-use equipment.
Report Delivery
Apply pressure to the puncture site for a few minutes. You may resume your normal activities immediately.
Timeline: Reports are available 10 days after the sample is received. Samples submitted by 11 am follow the same reporting schedule.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect Salmonella typhi DNA in whole blood using PCR technology. It may support early and accurate diagnosis of typhoid/enteric fever, helping clinicians plan appropriate management.
How to Prepare
- Collect 4 mL whole blood in lavender top (EDTA) tube; minimum 2 mL required.
- Transport the sample refrigerated.
- Do not freeze the sample.
- Send sample with the completed request form and patient identification.
Doctor's Notes
Reviewed by Dr Kothari Ramesh Shantilal — MBBS, MD (Microbiology) · Reg. No. 27670
"PCR for S. typhi DNA can be valuable in early or clinically suspected enteric fever, especially when blood culture may be negative due to prior antibiotics. However, the result must be interpreted with the full clinical picture."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Frozen whole blood sample
- Clotted sample
- Insufficient sample volume (less than 2 mL)
- Incorrect or mislabelled sample container
Understanding Your Results
Positive / Detected
Salmonella typhi DNA was detected in the blood sample. This is consistent with typhoid/enteric fever; clinical correlation is required.
Negative / Not detected
Salmonella typhi DNA was not detected. This does not exclude typhoid infection; clinical correlation and further testing may be advised.
Consult a doctor if you have persistent fever with abdominal pain, headache, weakness, vomiting, constipation or diarrhoea, especially after travel to or residence in areas where typhoid is common.
Limitations
- ⚠PCR detects DNA, not live bacteria, so it does not provide antibiotic susceptibility information
- ⚠A negative result does not completely exclude typhoid infection
- ⚠Clinical correlation and additional laboratory testing may be required
- ⚠Culture should be performed if antimicrobial sensitivity testing is needed
Risks & Considerations
- ●Mild pain or bruising at the needle site
- ●Dizziness or lightheadedness during blood collection
- ●Rare infection at the puncture site
Interfering Factors
- ●Prior antibiotic therapy may reduce bacterial load and affect detection
- ●Intermittent bacteraemia may influence test sensitivity
- ●Frozen whole blood sample must not be used
- ●Improper sample collection or transport may affect PCR quality
Compare With Similar Tests
| Test | Typhoid DNA Detection Test | Typhoid DNA PCR vs Widal Test | Typhoid DNA PCR vs Blood Culture |
|---|---|---|---|
| Comparison | Typhoid DNA Detection Test |
Frequently Asked Questions
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
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