Skip to main content
DNA Labs India

UGT1A1 Gene Gilbert syndrome NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

UGT1A1 Gene Gilbert syndrome NGS Genetic Test

Short Name: Gilbert Syndrome NGS Test

Also known as: Gilbert Syndrome Genetic Test, UGT1A1 Mutation Analysis, Gilbert's Disease DNA Test

UGT1A1 Gene Gilbert syndrome NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood, Extracted DNA, or One drop Blood on FTA Card samples. Results in 3-4 weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

To diagnose Gilbert syndrome by identifying mutations in the UGT1A1 gene using next-generation sequencing (NGS) technology, enabling accurate clinical management and genetic counseling.

Test Code
5399
Price
₹20,000
Sample Type
Blood, Extracted DNA, or One drop Blood on FTA Card
Result Time
3-4 weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Provide detailed clinical history and undergo a genetic counseling session to draw a pedigree chart of family members affected with Gilbert syndrome.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample collected via venipuncture from a vein in the arm, or use of extracted DNA or FTA card with one drop of blood.

Step 3

Report Delivery

Sample is labeled, stored at ambient room temperature, and sent to the laboratory for NGS analysis.

Timeline: 3-4 weeks

Patient Instructions

1
Before the Test:Genetic counseling session and review of clinical history to assess indications for testing.
2
During the Test:Blood sample collection via venipuncture or alternative methods as specified.
3
After the Test:Wait for report delivery in 3-4 weeks and follow up with physician for interpretation and next steps.

About This Test

Who Should Get This Test

To diagnose Gilbert syndrome by identifying mutations in the UGT1A1 gene using next-generation sequencing (NGS) technology, enabling accurate clinical management and genetic counseling.

How to Prepare

  • Collect blood in an EDTA tube or use extracted DNA
  • Ensure proper labeling with patient details
  • Avoid hemolysis during blood draw
  • Store sample at room temperature if not processed immediately

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"This genetic test is crucial for confirming Gilbert syndrome, guiding management, and differentiating from other liver disorders. Early detection helps in symptom control and family planning."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood, Extracted DNA, or One drop Blood on FTA Card
Collection MethodVenipuncture

Sample Stability

Stable at room temperature for up to 24 hours
Extracted DNA stable at -20°C for long-term storage
Sample Rejection Criteria:
  • Hemolyzed or clotted blood sample
  • Insufficient sample volume
  • Improper labeling or documentation

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the UGT1A1 gene associated with Gilbert syndrome. Genetic counseling is recommended for understanding implications.
Positive: Pathogenic variant detected, confirming Gilbert syndrome diagnosis
Negative: No pathogenic variants detected, suggesting absence of genetic cause
Variant of Uncertain Significance (VUS): Mutation found but clinical significance unknown, requiring further evaluation
⚠️ When to Consult a Doctor:

Consult a hepatologist or geneticist if symptoms persist, worsen, or if there is a family history of liver disorders. Seek guidance for genetic counseling and management.

Limitations

  • ⚠May not detect all rare or novel mutations in the UGT1A1 gene
  • ⚠Requires genetic counseling for interpretation of results
  • ⚠Does not assess for other liver disorders or bilirubin metabolism issues

Risks & Considerations

  • ●Minor bruising or discomfort at the puncture site
  • ●Rare risk of infection or bleeding
  • ●Emotional impact of genetic results, requiring counseling support

Interfering Factors

  • ●Poor sample quality or degradation
  • ●Contamination during sample collection or processing
  • ●Recent blood transfusions affecting DNA analysis

Frequently Asked Questions

What is Gilbert syndrome?
Gilbert syndrome is a benign genetic disorder affecting bilirubin metabolism in the liver, caused by mutations in the UGT1A1 gene, leading to intermittent jaundice.
What are the common symptoms of Gilbert syndrome?
Symptoms may include yellowing of skin and eyes (jaundice), fatigue, abdominal discomfort, nausea, and loss of appetite, often triggered by stress or fasting.
How is Gilbert syndrome diagnosed?
Diagnosis involves blood tests for elevated bilirubin levels and genetic testing to identify UGT1A1 gene mutations, with NGS providing accurate results.
What is the UGT1A1 Gene NGS Genetic Test?
It is a next-generation sequencing test that analyzes the entire UGT1A1 gene for mutations associated with Gilbert syndrome, offering high accuracy.
What is the cost of this test?
The test costs INR 20000, which includes home sample collection across India.
What sample type is required for the test?
Blood, extracted DNA, or one drop of blood on an FTA card can be used for sample collection.
Is fasting required before the test?
No, fasting is not required. The test can be done at any time with ambient room temperature preparation.
How long does it take to get results?
Results are typically delivered within 3-4 weeks via online portal, email, or WhatsApp.
What are the benefits of this genetic test?
Benefits include accurate diagnosis, identification of specific mutations, carrier status determination for family planning, and early detection for management.
Are there any risks associated with the test?
Risks are minimal, such as bruising at the blood draw site. Genetic results may have emotional implications, so counseling is advised.
Who should consider getting this test?
Individuals with unexplained jaundice, family history of Gilbert syndrome, elevated bilirubin levels, or symptoms suggestive of the condition.
What should I do after receiving the test results?
Consult a healthcare provider or geneticist for interpretation, management options, and genetic counseling if needed.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

NR1H4 Gene Cholestasis, infantile, NR1H4 related NGS Genetic Test

₹20,000

UGT1A1 Gene Crigler-Najjar syndrome, type 1 NGS Genetic Test

₹20,000

UGT1A1 Gene Crigler-Najjar syndrome, type 2 NGS Genetic Test

₹20,000

ABCC2 Gene Dubin-Johnson syndrome NGS Genetic Test

₹20,000

NBAS Gene Infantile liver failure syndrome type 2 NGS Genetic Test

₹20,000

Criggler Najjar Syndrome

₹27,000
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.