Varicella Zoster Virus (VZV) Antibody IgM Test
Short Name: VZV IgM Antibody Test
Also known as: VZV IgM, Varicella Zoster IgM, Chickenpox IgM, Shingles IgM
Varicella Zoster Virus (VZV) Antibody IgM Test test available at DNA Labs India for ₹1,381. Uses CLIA (Chemiluminescence Immunoassay) on Serum samples. Results in Reports are usually available on the same day if the blood sample reaches the laboratory by 9 AM.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Kothari Ramesh Shantilal
Consultant Microbiologist · Reg: 27670
Last reviewed: September 7, 2026
Overview
This test is used to detect IgM antibodies against the varicella zoster virus. The presence of IgM indicates a recent or currently active VZV infection. It assists in diagnosing chickenpox (varicella) or shingles (herpes zoster), particularly in atypical cases, immunocompromised patients, or when exposure history is unclear.
- Test Code
- 3726
- Price
- ₹1,381
- Sample Type
- Serum
- Result Time
- Reports are usually available on the same day if the blood sample reaches the laboratory by 9 AM.
- Fasting Required
- No
- Method
- CLIA (Chemiluminescence Immunoassay)
Sample Collection
No special preparation is required. However, inform your doctor about any medications, recent blood transfusions, or vaccinations.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm. You may feel a slight prick during insertion of the needle.
Report Delivery
Apply gentle pressure to the puncture site for a few minutes. You can resume normal activities immediately.
Timeline: Reports are usually available on the same day if the blood sample reaches the laboratory by 9 AM.
Patient Instructions
About This Test
Who Should Get This Test
This test is used to detect IgM antibodies against the varicella zoster virus. The presence of IgM indicates a recent or currently active VZV infection. It assists in diagnosing chickenpox (varicella) or shingles (herpes zoster), particularly in atypical cases, immunocompromised patients, or when exposure history is unclear.
How to Prepare
- No special preparation required
- Blood to be collected in a Serum Separator Tube (SST)
- Ship sample refrigerated or frozen
Doctor's Notes
Reviewed by Dr Kothari Ramesh Shantilal — MBBS, MD (Microbiology) · Reg. No. 27670
"This test is valuable for confirming recent VZV exposure, especially when clinical signs are atypical. A negative result in early infection does not exclude disease, so serial testing is advised."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or lipemic serum sample
- Improperly labeled sample
- Clotted or contaminated specimen
- Sample received after prolonged storage at room temperature
Understanding Your Results
If the test is positive or if you develop symptoms such as a rash with fever, especially if you are pregnant, immunocompromised, or caring for newborns, consult your physician promptly.
Limitations
- ⚠IgM may be negative in the first few days of infection
- ⚠Positive IgM can persist for up to 3–6 months, so it does not always indicate acute infection
- ⚠False-positive results have been reported in pregnancy, autoimmune diseases, and other viral infections
- ⚠Individuals with weakened immune systems may have a delayed or absent IgM response
- ⚠A negative result does not exclude VZV infection; repeat testing after 2–3 weeks is recommended
Risks & Considerations
- ●Mild pain or bruising at the needle site
- ●Minor bleeding after needle removal
- ●Infection at the puncture site (rare)
- ●Lightheadedness or fainting (rare)
Interfering Factors
- ●Recent blood transfusion (within 3 months) may dilute antibodies
- ●Rheumatoid factor or heterophile antibodies can cause false-positive results
- ●Cross-reactivity with other herpesviruses (HSV, CMV, EBV)
- ●Immunosuppression may reduce antibody production
- ●Very early infection (before IgM develops) can yield false-negative results
Compare With Similar Tests
| Test | Varicella Zoster Virus (VZV) Antibody IgM Test | ||
|---|---|---|---|
| Comparison | Varicella Zoster Virus (VZV) Antibody IgM Test |
Frequently Asked Questions
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