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DNA Labs India

VDR Gene Rickets, vitamin D-resistant, type 2A NGS Genetic Test

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VDR Gene Rickets, vitamin D-resistant, type 2A NGS Genetic Test

Short Name: VDR Gene Rickets Test

Also known as: Hereditary vitamin D-resistant rickets, VDR gene mutation rickets

VDR Gene Rickets, vitamin D-resistant, type 2A NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To diagnose vitamin D-resistant rickets type 2A by detecting mutations in the VDR gene using next-generation sequencing, enabling accurate treatment and management.

Test Code
2464
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Clinical history of the patient and a genetic counseling session to draw a pedigree chart of family members affected with VDR gene rickets.

Method: Venipuncture or FTA Card

Step 2

Laboratory Analysis

Standard blood collection procedure or use of FTA card for one drop of blood.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bleeding. Store sample as per instructions.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Provide clinical history and undergo genetic counseling. No fasting required.
2
During the Test:Blood sample collection via venipuncture or FTA card.
3
After the Test:Monitor the puncture site for any discomfort. Reports will be available in 3-4 weeks.

About This Test

Who Should Get This Test

To diagnose vitamin D-resistant rickets type 2A by detecting mutations in the VDR gene using next-generation sequencing, enabling accurate treatment and management.

How to Prepare

  • Ensure proper identification of the patient
  • Use sterile equipment for blood collection
  • Label samples correctly with patient details

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Early genetic testing for VDR gene mutations can guide treatment and management of vitamin D-resistant rickets, improving patient outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture or FTA Card
Sample Rejection Criteria:
  • Hemolyzed or contaminated samples
  • Insufficient sample volume
  • Improper labeling

Understanding Your Results

Results indicate the presence or absence of mutations in the VDR gene. Positive results confirm diagnosis, while negative results may require further clinical evaluation.
📊

Pathogenic variant detected

Confirms diagnosis of VDR gene rickets type 2A. Genetic counseling recommended.

📊

No pathogenic variant detected

VDR gene mutations not found. Consider other causes of rickets or repeat testing if clinically indicated.

⚠️ When to Consult a Doctor:

If symptoms of rickets are present, such as bone deformities or growth delays, or for genetic counseling after a positive test result.

Limitations

  • ⚠May not detect all rare variants or intronic mutations
  • ⚠Results should be correlated with clinical findings

Risks & Considerations

  • ●Minor pain or bruising at the blood draw site
  • ●Rare risk of infection

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA quality

Frequently Asked Questions

What is VDR Gene Rickets?
VDR Gene Rickets is a rare genetic disorder caused by mutations in the VDR gene, leading to vitamin D-resistant rickets type 2A, which affects bone health.
What are the common symptoms?
Symptoms include delayed growth, bowing of legs, spinal curvature, dental problems, muscle weakness, bone pain, and fractures.
How is VDR Gene Rickets diagnosed?
Diagnosis involves blood tests, X-rays, and genetic testing to detect mutations in the VDR gene.
What is the cost of the NGS Genetic Test in India?
The cost is INR 20,000, with free home sample collection available across India.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test in numerous cities.
How long does it take to get the test reports?
Reports are typically available within 3 to 4 weeks after sample collection.
Is the test covered by insurance?
Coverage depends on your insurance plan. It is not universally covered, so check with your provider.
What sample type is required for the test?
Blood, extracted DNA, or one drop of blood on an FTA card can be used.
Do I need to fast before the test?
No, fasting is not required for this genetic test.
What is the accuracy of the NGS Genetic Test?
NGS provides high accuracy for detecting gene mutations, but results should be interpreted with clinical findings.
Can this test be performed on children?
Yes, the test can be performed on individuals of all ages, including children, with appropriate sample collection.
How do I book the test?
You can book the test online through DNA Labs India's website or contact them via phone or WhatsApp for assistance.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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