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DNA Labs India

Venous Thrombosis Risk Analysis Panel Test

DNA Labs India | ISO 9001:2015 Certified

Venous Thrombosis Risk Analysis Panel Test

Short Name: VTRAP

Also known as: VTRAP, Venous Thrombosis Risk Panel

Venous Thrombosis Risk Analysis Panel Test test available at DNA Labs India for ₹7,500. Uses Real Time PCR on Whole Blood samples. Results in Samples are accepted Monday/Thursday by 11 am, and reports are issued Wednesday/Saturday as per the laboratory schedule.. Free home collection in 300+ cities across India.

Genetic / Coagulation🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of this panel is to detect specific inherited genetic variations in the Factor V Leiden, Prothrombin, and MTHFR genes that may increase the risk of developing venous thromboembolism. It is not a test for diagnosing an acute blood clot, but rather a risk-assessment tool that helps clinicians understand the underlying genetic predisposition in selected patients.

Test Code
3741
Price
₹7,500
Sample Type
Whole Blood
Result Time
Samples are accepted Monday/Thursday by 11 am, and reports are issued Wednesday/Saturday as per the laboratory schedule.
Fasting Required
No
Method
Real Time PCR
Step 1

Sample Collection

No special preparation required. No fasting needed.

Method: Venipuncture

Step 2

Laboratory Analysis

A qualified phlebotomist will collect about 5 mL of blood from a vein in your arm using EDTA tubes. The collection takes only a few minutes.

Step 3

Report Delivery

You may resume normal activities immediately after sample collection. Apply pressure to the puncture site to reduce bruising if advised.

Timeline: Samples are accepted Monday/Thursday by 11 am, and reports are issued Wednesday/Saturday as per the laboratory schedule.

Patient Instructions

1
Before the Test:No fasting or special preparation is required before providing the blood sample.
2
During the Test:A blood sample is drawn from a vein in your arm. The procedure is quick and generally well tolerated.
3
After the Test:You can leave immediately after sample collection and continue your daily routine.

About This Test

Who Should Get This Test

The purpose of this panel is to detect specific inherited genetic variations in the Factor V Leiden, Prothrombin, and MTHFR genes that may increase the risk of developing venous thromboembolism. It is not a test for diagnosing an acute blood clot, but rather a risk-assessment tool that helps clinicians understand the underlying genetic predisposition in selected patients.

How to Prepare

  • No special preparation or fasting is required.
  • Informed consent for genetic testing should be obtained.
  • Sample must be transported refrigerated and must not be frozen.

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"A positive genetic thrombophilia marker should always be interpreted with clinical history and family history. A DNA result alone does not automatically mean long-term anticoagulation is needed."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole Blood
Sample Volume5 mL (3 mL minimum)
Container2 Lavender Top (EDTA) tubes
Collection MethodVenipuncture

Sample Stability

Room Temperature6 hours
Refrigerated72 hours
FrozenNot acceptable - DO NOT FREEZE
Sample Rejection Criteria:
  • Clotted or haemolysed sample
  • Frozen sample
  • Improperly labelled sample
  • Sample volume less than 3 mL

Understanding Your Results

This panel is a risk-assessment tool. A 'negative' result means none of the tested variants were detected; it does not rule out all causes of thrombosis. A 'positive' result indicates that a variant has been detected, but the clinical action depends on the gene, zygosity, personal history, and family history.
📊

Not detected

No mutation identified in the tested variants. This does not exclude the possibility of venous thromboembolism from other causes.

📊

Detected - Heterozygous

One copy of the variant was detected. Clinical significance depends on the specific gene and the individual's personal and family history.

📊

Detected - Homozygous

Two copies of the variant were detected. This may be associated with a higher inherited risk for certain variants, especially Factor V Leiden. Specialist consultation is recommended.

⚠️ When to Consult a Doctor:

Consult a haematologist or clinical geneticist for proper interpretation of this panel. If you develop sudden leg pain, swelling, warmth, chest pain, shortness of breath, or coughing up blood, seek emergency medical care immediately.

Limitations

  • This panel covers only selected genetic variants; a negative result does not exclude all inherited or acquired thrombophilias.
  • The clinical significance of MTHFR variants in VTE risk is debated and should be interpreted cautiously.
  • All results should be interpreted by a qualified haematologist or clinical geneticist in the context of personal and family history.

Risks & Considerations

  • Minor bruising at the puncture site
  • Mild bleeding
  • Hematoma
  • Dizziness or faintness
  • Rare risk of infection at the venepuncture site

Interfering Factors

  • Anticoagulant therapy does not interfere with DNA-based PCR testing.
  • Degraded or poor-quality DNA may lead to amplification failure.

Frequently Asked Questions

What is the Venous Thrombosis Risk Analysis Panel (VTRAP)?
It is a blood-based PCR test that looks for genetic variants in Factor V Leiden, Prothrombin and MTHFR genes to help assess the risk of developing venous thromboembolism.
How much does the VTRAP test cost?
At DNA Labs India, the VTRAP test costs Rs 7500. Prices may vary by location and laboratory. Free home sample collection is included for online bookings.
Do I need to fast before the VTRAP test?
No. No special preparation or fasting is required. You can provide the blood sample at a convenient time.
What sample is needed for this test?
About 5 mL of whole blood collected in two lavender-top EDTA tubes is required. At least 3 mL is the minimum sample volume.
Which genes are tested in this panel?
The panel tests for Factor V Leiden mutation, Prothrombin gene mutation, and MTHFR gene mutation.
Who should consider taking this test?
People with suspected thrombophilia, APC resistance, family history of Factor V Leiden, personal or family history of VTE, or selected women planning oral contraceptive use or pregnancy may consider this test.
Does a negative result mean I will never develop blood clots?
No. A negative result only means the tested genetic markers were not found. Other acquired and genetic risk factors may still lead to VTE.
What does a positive Factor V Leiden result mean?
A heterozygous Factor V Leiden result increases the risk of VTE by about 8-fold; homozygous carriers have a much higher risk, about 80-100 fold. This result should always be interpreted with clinical history.
Can this test be done while taking anticoagulant drugs?
Yes. The test detects DNA, so anticoagulant therapy does not affect the PCR result.
Is home sample collection available for this test?
Yes. Free home sample collection is provided across multiple cities in India for online bookings.
When will I get my report?
Samples are accepted Monday/Thursday by 11 am, and reports are issued Wednesday/Saturday, subject to laboratory schedule.
Is this test covered by insurance?
Coverage depends on your insurance policy. Check with your provider; some policies may cover clinically indicated thrombophilia testing, but pre-approval is recommended.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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