VZV (Varicella Zoster Virus) (RNA Detection) Qualitative Test
Short Name: VZV RNA Qualitative
Also known as: VZV PCR, Varicella Zoster Virus RNA Detection, Chickenpox PCR, Shingles PCR
VZV (Varicella Zoster Virus) (RNA Detection) Qualitative Test test available at DNA Labs India for ₹5,780. Uses Real Time PCR on Serum, Plasma, Whole blood, Saliva, CSF, Swabs (vesicle, papule, crust), Lymph node biopsy samples. Results in Reports are available on the 4th working day. Email reports within 48 hours, phone within 36 hours.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Kothari Ramesh Shantilal
Consultant Microbiologist · Reg: 27670
Last reviewed: September 7, 2026
Overview
The purpose of the VZV RNA Qualitative Test is to confirm active VZV infection by detecting viral RNA. It aids in diagnosing chickenpox and shingles, especially when clinical presentation is unclear. It also helps monitor disease progression and response to antiviral therapy. In immunocompromised patients, early detection is critical to prevent severe complications. The test is also used for diagnosing VZV encephalitis or meningitis via CSF analysis.
- Test Code
- 6251
- CPT Code
- 87529
- ICD Code
- B01.9
- Price
- ₹5,780
- Sample Type
- Serum, Plasma, Whole blood, Saliva, CSF, Swabs (vesicle, papule, crust), Lymph node biopsy
- Result Time
- Reports are available on the 4th working day. Email reports within 48 hours, phone within 36 hours.
- Fasting Required
- No
- Method
- Real Time PCR
Sample Collection
No special preparation required. Inform your doctor about any medications you are taking, especially antiviral drugs. A consent form must be signed before sample collection.
Method: Venipuncture or swab collection
Laboratory Analysis
Blood sample will be drawn from a vein in your arm. For swabs, a sterile swab will be rubbed over the lesion. The procedure is quick and minimally invasive.
Report Delivery
You can resume normal activities immediately. There are no restrictions after sample collection.
Timeline: Reports are available on the 4th working day. Email reports within 48 hours, phone within 36 hours.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the VZV RNA Qualitative Test is to confirm active VZV infection by detecting viral RNA. It aids in diagnosing chickenpox and shingles, especially when clinical presentation is unclear. It also helps monitor disease progression and response to antiviral therapy. In immunocompromised patients, early detection is critical to prevent severe complications. The test is also used for diagnosing VZV encephalitis or meningitis via CSF analysis.
How to Prepare
- For blood: Collect in EDTA tube, mix gently.
- For swabs: Use sterile swab, place in viral transport medium.
- For CSF: Collect in sterile vial, transport immediately.
- Label all samples with patient ID and date/time of collection.
- Transport samples to laboratory at 2-8°C if delayed.
Doctor's Notes
Reviewed by Dr Kothari Ramesh Shantilal — MBBS, MD (Microbiology) · Reg. No. 27670
"Early detection of VZV RNA is crucial for initiating antiviral therapy, especially in immunocompromised patients. This test offers high sensitivity and specificity, aiding in accurate diagnosis and management."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed blood samples
- Samples with insufficient volume
- Samples not stored at appropriate temperature
- Unlabeled or mislabeled samples
- Samples received after prolonged delay
Understanding Your Results
Detected
Positive for VZV RNA. Active VZV infection confirmed. Clinical correlation and treatment as per physician's advice.
Not Detected
Negative for VZV RNA. No evidence of active VZV infection. If symptoms persist, consider other diagnostic tests.
Consult a doctor if you experience symptoms such as fever, rash, blisters, or neurological signs like severe headache, confusion, or seizures. Early diagnosis and treatment are crucial, especially for immunocompromised individuals.
Limitations
- ⚠Qualitative test does not quantify viral load
- ⚠Negative result does not completely rule out infection if sample quality is poor
- ⚠Test may not differentiate between latent and active infection in some cases
- ⚠Requires specialized laboratory equipment and trained personnel
Risks & Considerations
- ●Minimal risk of bleeding or bruising at needle site
- ●Slight discomfort during blood draw
- ●Rare risk of infection at collection site
Interfering Factors
- ●Improper sample collection or storage may degrade RNA, leading to false negatives
- ●Contamination with other genetic material may cause false positives
- ●Recent antiviral therapy may reduce viral load, affecting detection
- ●Sample taken from healed lesions may have low viral RNA
Compare With Similar Tests
| Test | VZV (Varicella Zoster Virus) (RNA Detection) Qualitative Test | VZV IgM Antibody Test | VZV IgG Antibody Test | VZV Antigen Detection Test | VZV Culture |
|---|---|---|---|---|---|
| Comparison | VZV (Varicella Zoster Virus) (RNA Detection) Qualitative Test |
Frequently Asked Questions
What is the cost of the VZV RNA Qualitative Test?
What sample is required for this test?
Do I need to fast before the test?
How long does it take to get results?
Is home sample collection available?
What does a positive result mean?
What does a negative result mean?
Can this test differentiate between chickenpox and shingles?
Is this test recommended for immunocompromised patients?
Are there any risks associated with the test?
Can I take antiviral medication before the test?
Is the test NABL accredited?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
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