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WNT1 Gene Osteogenesis imperfecta type 15 NGS Genetic Test

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WNT1 Gene Osteogenesis imperfecta type 15 NGS Genetic Test

Short Name: WNT1 OI Type 15 NGS Test

Also known as: Osteogenesis Imperfecta Type 15, WNT1-related OI

WNT1 Gene Osteogenesis imperfecta type 15 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

Next Generation Sequencing🏠 Home Collection

🩺 Medically Reviewed By

Overview

To diagnose Osteogenesis Imperfecta Type 15 by identifying pathogenic mutations in the WNT1 gene using Next Generation Sequencing technology.

Test Code
5092
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
Next Generation Sequencing (NGS)
Step 1

Sample Collection

Clinical history and genetic counseling session recommended.

Method: Blood draw

Step 2

Laboratory Analysis

Blood sample collected via venipuncture.

Step 3

Report Delivery

Sample sent to laboratory for analysis.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling and clinical evaluation recommended.
2
During the Test:Blood sample collection procedure.
3
After the Test:Results reviewed and interpreted by a genetic expert.

About This Test

Who Should Get This Test

To diagnose Osteogenesis Imperfecta Type 15 by identifying pathogenic mutations in the WNT1 gene using Next Generation Sequencing technology.

How to Prepare

  • Ensure proper sample labeling
  • Follow aseptic techniques

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early diagnosis through genetic testing can guide management and improve outcomes for patients with OI Type 15."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodBlood draw

Sample Stability

Blood sample stable for 7 days at room temperature
Sample Rejection Criteria:
  • Hemolyzed sample
  • Insufficient sample volume

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the WNT1 gene associated with OI Type 15.
Positive: Pathogenic variant detected, consistent with OI Type 15 diagnosis
Negative: No pathogenic variants detected, but clinical correlation is advised
Variant of uncertain significance: Further testing or family studies may be needed
⚠️ When to Consult a Doctor:

If symptoms suggestive of OI Type 15 are present, or if there is a family history of the condition.

Limitations

  • May not detect all genetic variants
  • Requires genetic counseling for interpretation

Risks & Considerations

  • Minimal risk from blood draw
  • Potential psychological impact of results

Interfering Factors

  • Poor sample quality
  • Contamination

Compare With Similar Tests

TestWNT1 Gene Osteogenesis imperfecta type 15 NGS Genetic TestCOL1A1 Gene OI TestWhole Exome Sequencing
ComparisonWNT1 Gene Osteogenesis imperfecta type 15 NGS Genetic TestFor other types of Osteogenesis ImperfectaBroader genetic analysis for multiple disorders

Frequently Asked Questions

What is the WNT1 Gene OI Type 15 NGS Genetic Test?
It is a genetic test that uses Next Generation Sequencing to detect mutations in the WNT1 gene, which causes Osteogenesis Imperfecta Type 15.
How much does the test cost?
The test costs INR 20,000 at DNA Labs India, including result analysis.
What sample type is required?
Blood, extracted DNA, or one drop of blood on an FTA card.
How long does it take to get results?
Results are typically available in 3 to 4 weeks.
Is home sample collection available?
Yes, free home collection is available for online bookings across India.
What are the symptoms of OI Type 15?
Symptoms include frequent fractures, short stature, bowed limbs, weak muscles, loose joints, and blue or gray sclera.
How is the test performed?
A blood sample is collected and analyzed using NGS technology to identify WNT1 gene mutations.
What does a positive result mean?
A positive result indicates a pathogenic variant in the WNT1 gene, confirming OI Type 15 diagnosis.
Is genetic counseling recommended?
Yes, genetic counseling is advised before and after testing to understand implications and family risks.
Can the test be used for prenatal diagnosis?
It may be used in prenatal settings, but consult a genetic specialist for guidance.
What is the accuracy of the test?
NGS technology provides high accuracy, but results should be interpreted by a genetic expert.
How do I book the test?
Book online via DNA Labs India's website or contact their customer service for assistance.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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