ABCB1 Gene Colchicine resistance NGS Genetic Test
Short Name: ABCB1 Colchicine Resistance Test
Also known as: ABCB1 Gene Colchicine Resistance Test, Colchicine Resistance Genetic Test, ABCB1 NGS Test for Gout
ABCB1 Gene Colchicine resistance NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS (Next-Generation Sequencing) on Blood samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to determine if an individual has a genetic predisposition to colchicine resistance by analyzing mutations in the ABCB1 gene, aiding in the diagnosis and management of gout and related inflammatory conditions.
- Test Code
- 4653
- Price
- ₹20,000
- Sample Type
- Blood
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- NGS (Next-Generation Sequencing)
Sample Collection
No special preparation required. Inform the healthcare provider about any medications or medical history.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm by a trained phlebotomist.
Report Delivery
Apply pressure to the puncture site with a cotton ball to stop bleeding. Avoid strenuous activity for a few hours.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to determine if an individual has a genetic predisposition to colchicine resistance by analyzing mutations in the ABCB1 gene, aiding in the diagnosis and management of gout and related inflammatory conditions.
How to Prepare
- Ensure proper patient identification
- Use sterile equipment
- Label sample correctly
- Transport sample at ambient temperature
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is crucial for personalizing treatment in gout patients by identifying genetic resistance to colchicine, helping avoid ineffective therapies and guiding alternative options."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Insufficient volume
- Incorrect sample type
- Contaminated sample
Understanding Your Results
Positive
Pathogenic variant detected in ABCB1 gene, indicating likely resistance to colchicine
Action: Consider alternative treatments and genetic counseling
Negative
No pathogenic variants detected, suggesting normal response to colchicine
Action: Proceed with standard colchicine therapy if indicated
Variant of Uncertain Significance
Genetic variant found but clinical significance unknown
Action: Further testing and clinical correlation recommended
Consult a doctor if you experience symptoms of gout such as severe joint pain, swelling, or if colchicine treatment is ineffective. Genetic counseling is advised before and after testing.
Limitations
- ⚠May not detect all genetic variants
- ⚠Results should be correlated with clinical findings
- ⚠Does not replace comprehensive clinical evaluation
- ⚠Limited to ABCB1 gene analysis only
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection at puncture site
- ●Psychological impact of genetic results
- ●No significant physical risks
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
- ●Hemolyzed blood sample
- ●Recent blood transfusion
Compare With Similar Tests
| Test | ABCB1 Gene Colchicine resistance NGS Genetic Test | ABCB1 Gene Full Sequencing | Gout Panel Test | Pharmacogenomics Panel |
|---|---|---|---|---|
| Comparison | ABCB1 Gene Colchicine resistance NGS Genetic Test |
Frequently Asked Questions
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
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