COMT Genotyping Test
Short Name: COMT Genotyping
Also known as: COMT Gene Test, Catechol-O-Methyltransferase Genotyping
COMT Genotyping Test test available at DNA Labs India for ₹42,120. Uses PCR, Sequencing on Whole blood samples. Results in Reports are typically available within 10 working days after the sample is received by the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To identify variations in the COMT gene that may affect the metabolism of catecholamines like dopamine, aiding in the diagnosis and treatment of related conditions such as Parkinson's disease, schizophrenia, anxiety, and depression.
- Test Code
- 344
- Price
- ₹42,120
- Sample Type
- Whole blood
- Result Time
- Reports are typically available within 10 working days after the sample is received by the laboratory.
- Fasting Required
- No
- Method
- PCR, Sequencing
Sample Collection
Complete and submit the Genomics Clinical Information Requisition Form (Form 20). No fasting required.
Method: Venipuncture
Laboratory Analysis
A blood sample will be collected via venipuncture into an EDTA tube by a trained phlebotomist.
Report Delivery
The sample will be labeled, stored refrigerated, and shipped to the laboratory. Do not freeze.
Timeline: Reports are typically available within 10 working days after the sample is received by the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
To identify variations in the COMT gene that may affect the metabolism of catecholamines like dopamine, aiding in the diagnosis and treatment of related conditions such as Parkinson's disease, schizophrenia, anxiety, and depression.
How to Prepare
- Fill out Form 20 accurately before sample collection.
- Ensure the blood sample is collected in the specified EDTA tube.
- Ship the sample refrigerated within 24 hours of collection.
- Avoid freezing the sample as it may compromise results.
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"COMT genotyping can aid in understanding genetic predispositions affecting neurotransmitter metabolism, which is valuable for personalized healthcare strategies."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume (less than 4 mL)
- Unlabeled or mislabeled sample
- Sample not refrigerated or frozen
- Missing or incomplete Form 20
Understanding Your Results
If you experience symptoms such as difficulty focusing, anxiety, impulsiveness, or have a family history of conditions like Parkinson's disease or schizophrenia, consult a healthcare provider for evaluation and potential testing.
Limitations
- ⚠Test analyzes only specific COMT gene variants
- ⚠Results should be interpreted in conjunction with clinical symptoms and history
- ⚠Does not diagnose conditions alone but indicates genetic predisposition
Risks & Considerations
- ●Minor bruising or discomfort at the puncture site
- ●Rare risk of infection or excessive bleeding
- ●Slight feeling of lightheadedness during blood draw
Interfering Factors
- ●Contaminated or improperly stored sample
- ●Failure to provide required clinical information form
Frequently Asked Questions
What is the COMT Genotyping Test?
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What conditions are associated with COMT gene variations?
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Reference Laboratory Services
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
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