Tacrolimus Genotyping (CYP3A5) Test
Short Name: CYP3A5 Genotyping
Also known as: CYP3A5 Genotyping Test, Tacrolimus Pharmacogenetic Test, CYP3A5 Allele Test
Tacrolimus Genotyping (CYP3A5) Test test available at DNA Labs India for ₹7,000. Uses Real Time PCR on 3 ml (2 ml min.) whole blood in 1 Lavender top (EDTA) tube. samples. Results in Reports are typically available on Wednesday or Saturday following sample collection on Monday or Thursday.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
To determine the CYP3A5 genotype to guide personalized dosing of tacrolimus, ensuring efficacy while minimizing toxicity in patients undergoing immunosuppressive therapy, particularly after organ transplantation.
- Test Code
- 1419
- Price
- ₹7,000
- Sample Type
- 3 ml (2 ml min.) whole blood in 1 Lavender top (EDTA) tube.
- Result Time
- Reports are typically available on Wednesday or Saturday following sample collection on Monday or Thursday.
- Fasting Required
- No
- Method
- Real Time PCR
Sample Collection
No special preparation required. Fasting is not necessary.
Method: Venipuncture
Laboratory Analysis
A healthcare professional will collect a blood sample via venipuncture from a vein in the arm.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Keep the sample refrigerated as instructed.
Timeline: Reports are typically available on Wednesday or Saturday following sample collection on Monday or Thursday.
Patient Instructions
About This Test
Who Should Get This Test
To determine the CYP3A5 genotype to guide personalized dosing of tacrolimus, ensuring efficacy while minimizing toxicity in patients undergoing immunosuppressive therapy, particularly after organ transplantation.
How to Prepare
- Collect 3 ml whole blood in a Lavender top (EDTA) tube.
- Ship the sample refrigerated. DO NOT FREEZE.
- Ensure proper labeling and documentation.
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"This test is crucial for optimizing tacrolimus dosing in transplant patients, helping to minimize toxicity and improve graft survival."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample hemolyzed or clotted
- Incorrect sample type or volume
- Sample not refrigerated or frozen
Understanding Your Results
CYP3A5*1/*1
CYP3A5*1/*3
CYP3A5*3/*3
If you experience symptoms of tacrolimus toxicity such as nausea, vomiting, diarrhea, tremors, high blood pressure, or vision changes, contact your doctor immediately for evaluation and possible dose adjustment.
Limitations
- ⚠This test does not measure tacrolimus blood levels; it only provides genetic predisposition.
- ⚠Other genes and factors (e.g., CYP3A4, drug interactions) may influence tacrolimus metabolism.
- ⚠Results should be used in conjunction with clinical assessment and therapeutic drug monitoring.
Risks & Considerations
- ●Minor bruising or pain at the puncture site
- ●Rare risk of infection or dizziness
Frequently Asked Questions
What is the Tacrolimus Genotyping (CYP3A5) Test?
Why is this test important for organ transplant patients?
What is the cost of the Tacrolimus Genotyping (CYP3A5) Test at DNA Labs India?
How is the sample collected for this test?
What do the test results mean?
How long does it take to get the test results?
Is fasting required for this test?
What are the symptoms of tacrolimus toxicity?
How does CYP3A5 genotype affect tacrolimus dosing?
Can this test be done at home?
Is the test covered by insurance?
Who should order the Tacrolimus Genotyping (CYP3A5) Test?
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