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Acute Lymphoblastic Leukemia (ALL) Cytogenetics Panel Test

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Acute Lymphoblastic Leukemia (ALL) Cytogenetics Panel Test

Acute Lymphoblastic Leukemia (ALL) Cytogenetics Panel Test test available at DNA Labs India for ₹20,000. Uses FISH, Conventional Karyotyping on Whole Blood and Bone Marrow samples. Results in Results are typically available within 4 working days after sample receipt.. Free home collection in 300+ cities across India.

Cytogenetics PanelAll Ages🏠 Home Collection

🩺 Medically Reviewed By

Overview

The ALL Cytogenetics Panel Test is performed to detect specific chromosomal abnormalities that are critical for diagnosing Acute Lymphoblastic Leukemia (ALL). These abnormalities include: *BCR/ABL or Philadelphia translocation, *t(variable;11q23); MLL gene breakapart, *t(12;21)(p13;q22); TEL/AML1, and *Chromosome analysis for hematological malignancy. Identifying these genetic changes helps in confirming the diagnosis, determining the subtype of ALL, assessing prognosis, and guiding targeted therapy decisions.

Test Code
58
Price
₹20,000
Sample Type
Whole Blood and Bone Marrow
Result Time
Results are typically available within 4 working days after sample receipt.
Fasting Required
No
Method
FISH, Conventional Karyotyping
Step 1

Sample Collection

A duly filled Chromosome and FISH analysis Requisition form (Form 17) is mandatory. Ensure proper documentation and sample labeling.

Method: Venipuncture for blood, Bone Marrow Aspiration

Step 2

Laboratory Analysis

Collection involves venipuncture for whole blood and bone marrow aspiration. Follow standard sterile techniques and patient comfort measures.

Step 3

Report Delivery

Samples should be shipped at 18-22°C. Do not freeze. Ensure timely transport to the laboratory for processing.

Timeline: Results are typically available within 4 working days after sample receipt.

Patient Instructions

1
Before the Test:Complete the mandatory Chromosome and FISH analysis Requisition form (Form 17). No fasting required, but follow any specific instructions from your healthcare provider.
2
During the Test:The test involves collecting blood and bone marrow samples, which may cause minimal discomfort. The process is performed by trained professionals.
3
After the Test:After sample collection, apply pressure to the puncture site to prevent bleeding. Monitor for any signs of infection or prolonged discomfort and report to your doctor.

About This Test

Who Should Get This Test

The ALL Cytogenetics Panel Test is performed to detect specific chromosomal abnormalities that are critical for diagnosing Acute Lymphoblastic Leukemia (ALL). These abnormalities include: *BCR/ABL or Philadelphia translocation, *t(variable;11q23); MLL gene breakapart, *t(12;21)(p13;q22); TEL/AML1, and *Chromosome analysis for hematological malignancy. Identifying these genetic changes helps in confirming the diagnosis, determining the subtype of ALL, assessing prognosis, and guiding targeted therapy decisions.

How to Prepare

  • Collect 8 mL (6 mL min.) whole blood from 2 Green Top (Sodium Heparin) tubes
  • Collect 4 mL (2 mL min.) bone marrow from 1 Green Top (Sodium Heparin) tube
  • Ship samples at 18-22°C; do not freeze
  • Include duly filled Chromosome and FISH analysis Requisition form (Form 17)
  • Maintain sample integrity during transport

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole Blood and Bone Marrow
Sample Volume8 mL whole blood and 4 mL bone marrow
ContainerGreen Top (Sodium Heparin) tubes
Collection MethodVenipuncture for blood, Bone Marrow Aspiration

Sample Stability

Room Temperature: 48 hours

Understanding Your Results

Results from the ALL Cytogenetics Panel Test help identify specific chromosomal abnormalities. A positive result indicates the presence of genetic changes associated with ALL, which may influence treatment approach. Negative results suggest no detectable abnormalities in the tested genes, but clinical correlation is essential.
📊

Positive for BCR/ABL (Philadelphia chromosome)

Indicates a subtype of ALL with targeted therapy options like tyrosine kinase inhibitors

📊

Positive for MLL gene rearrangements

Associated with certain ALL subtypes and may require intensive treatment

📊

Positive for TEL/AML1 translocation

Often linked to a favorable prognosis in pediatric ALL

📊

Abnormal chromosome analysis

Suggests chromosomal instability; further testing may be needed

📊

No abnormalities detected

Normal results, but clinical evaluation should continue if symptoms persist

⚠️ When to Consult a Doctor:

Consult a doctor immediately if you experience symptoms like fever, fatigue, bruising, or enlarged lymph nodes. Also, seek medical advice if test results are abnormal or if there are concerns about diagnosis and treatment options.

Risks & Considerations

  • Minor bruising or pain at the blood draw site
  • Slight risk of infection from bone marrow aspiration
  • Rare complications such as bleeding or hematoma

Frequently Asked Questions

What is the ALL Cytogenetics Panel Test?
It is a diagnostic test that analyzes chromosomal abnormalities in blood and bone marrow cells to aid in diagnosing Acute Lymphoblastic Leukemia (ALL).
Why is this test recommended?
To identify specific genetic changes like BCR/ABL or MLL rearrangements, which help in confirming ALL diagnosis, guiding treatment, and assessing prognosis.
What are the symptoms that indicate this test?
Symptoms include fever, fatigue, joint pain, weight loss, pale skin, easy bruising, enlarged lymph nodes, shortness of breath, and frequent infections.
How much does the test cost in India?
The test costs INR 20000 at DNA Labs India, with free home sample collection available across many cities.
What samples are required for the test?
8 mL of whole blood from 2 Sodium Heparin tubes and 4 mL of bone marrow from 1 Sodium Heparin tube are needed.
Is fasting required before the test?
No, fasting is not required, but a mandatory requisition form (Form 17) must be filled.
How is the test performed?
The test uses FISH (Fluorescence In Situ Hybridization) and conventional karyotyping methods to analyze chromosomes.
What is the turnaround time for results?
Results are typically available within 4 working days after sample collection.
Can this test be done at home?
Yes, DNA Labs India offers free home sample collection for this test in numerous cities across India.
What do abnormal results mean?
Abnormal results indicate chromosomal changes associated with ALL, which may require further evaluation and treatment planning by an oncologist.
Are there any risks with the test?
Risks are minimal and include bruising, pain at the collection site, or rare infection from bone marrow aspiration.
Is the test covered by insurance?
Coverage depends on your insurance policy. Check with your provider or schemes like PMJAY, CGHS, ECHS, ESIC, or private insurance for details.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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