B-Cell Rearrangement Detection Test
Short Name: B-Cell Rearrangement Detection
Also known as: B-cell Clonality Test, Immunoglobulin Gene Rearrangement Test, B-cell Malignancy Test
B-Cell Rearrangement Detection Test test available at DNA Labs India for ₹22,000. Uses PCR Fragment Analysis on Whole Blood samples. Results in Reports are delivered within 10-12 days after sample collection.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the B-Cell Rearrangement Detection Test is to detect clonal rearrangements in B-cell immunoglobulin genes, which helps in diagnosing B-cell lymphomas and leukemias, assessing tumor burden, and guiding therapeutic interventions.
- Test Code
- 1
- Price
- ₹22,000
- Sample Type
- Whole Blood
- Result Time
- Reports are delivered within 10-12 days after sample collection.
- Fasting Required
- No
- Method
- PCR Fragment Analysis
Sample Collection
Ensure the Genomics Clinical Information Requisition Form (Form 20) is duly filled. No fasting is required, but follow general blood draw preparation.
Method: Venipuncture
Laboratory Analysis
A healthcare professional will collect 4 mL of whole blood via venipuncture into a lavender top EDTA tube. Ensure proper labeling and handling.
Report Delivery
Ship the sample refrigerated; do not freeze. Await report delivery in 10-12 days via online portal, email, or WhatsApp.
Timeline: Reports are delivered within 10-12 days after sample collection.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the B-Cell Rearrangement Detection Test is to detect clonal rearrangements in B-cell immunoglobulin genes, which helps in diagnosing B-cell lymphomas and leukemias, assessing tumor burden, and guiding therapeutic interventions.
How to Prepare
- Fill Form 20 mandatory.
- Collect 4 mL (min 2 mL) whole blood in EDTA tube.
- Ship refrigerated, do not freeze.
- Maintain sample integrity during transport.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is essential for identifying clonal B-cell populations, aiding in the accurate diagnosis and treatment planning for lymphomas and leukemias."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Hemolyzed or clotted sample
- Missing or incomplete Form 20
- Improperly labeled or stored sample
Understanding Your Results
Negative
No clonal rearrangement detected. Suggests absence of B-cell malignancy, but clinical correlation is needed.
Positive
Clonal rearrangement detected. Indicates possible B-cell lymphoma or leukemia; further diagnostic tests recommended.
Consult a healthcare provider if symptoms such as swollen lymph nodes, fever, or weight loss persist, or if test results are positive for clonal rearrangement.
Limitations
- ⚠Cannot specify the exact subtype of lymphoma or leukemia; additional tests like flow cytometry or biopsy may be required.
- ⚠May not detect very low levels of clonal B-cells.
Risks & Considerations
- ●Minor bruising or discomfort at the blood draw site
- ●Rare risk of infection or hematoma
Interfering Factors
- ●Contaminated or hemolyzed blood sample
- ●Improper storage or shipping conditions
- ●Recent blood transfusions affecting DNA quality
Compare With Similar Tests
| Test | B-Cell Rearrangement Detection Test | Flow Cytometry | Bone Marrow Biopsy |
|---|---|---|---|
| Comparison | B-Cell Rearrangement Detection Test | Flow cytometry analyzes cell surface markers, while B-cell rearrangement detects genetic clonality. | Biopsy provides histological assessment; this test offers molecular detection of clonality. |
Frequently Asked Questions
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₹7,500Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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