ADAMTS13 Gene Thrombotic thrombocytopenic purpura NGS Genetic Test
Short Name: ADAMTS13 Gene TTP NGS Test
Also known as: TTP Genetic Test, ADAMTS13 Mutation Analysis, Thrombotic Thrombocytopenic Purpura DNA Test
ADAMTS13 Gene Thrombotic thrombocytopenic purpura NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the ADAMTS13 Gene NGS Genetic Test is to identify mutations in the ADAMTS13 gene that cause thrombotic thrombocytopenic purpura (TTP). This test aids in confirming a diagnosis of hereditary TTP, differentiating it from acquired forms, guiding personalized treatment plans, and providing genetic counseling for affected individuals and their families. It is recommended for patients with symptoms of TTP or a family history of the condition.
- Test Code
- 2694
- Price
- ₹20,000
- Sample Type
- Blood
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation is required. Provide clinical history and family pedigree information during genetic counseling.
Method: Venipuncture
Laboratory Analysis
A blood sample is collected via venipuncture by a trained phlebotomist. The process is quick and minimally invasive.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Resume normal activities immediately.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the ADAMTS13 Gene NGS Genetic Test is to identify mutations in the ADAMTS13 gene that cause thrombotic thrombocytopenic purpura (TTP). This test aids in confirming a diagnosis of hereditary TTP, differentiating it from acquired forms, guiding personalized treatment plans, and providing genetic counseling for affected individuals and their families. It is recommended for patients with symptoms of TTP or a family history of the condition.
How to Prepare
- Ensure proper identification of the patient
- Use sterile equipment
- Label the sample correctly
- Transport at ambient room temperature
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for ADAMTS13 mutations is essential for diagnosing hereditary TTP, enabling targeted treatment and family counseling."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Insufficient sample volume
- Incorrect labeling
- Contaminated sample
Understanding Your Results
No pathogenic variants
Low likelihood of hereditary TTP; consider other causes
Pathogenic variant detected
Confirms hereditary TTP; recommend treatment and family screening
Variant of uncertain significance
Further testing or clinical correlation needed
Consult a doctor if you experience symptoms of TTP, have a family history of the condition, or receive abnormal test results for further evaluation and management.
Limitations
- ⚠May not detect all possible mutations
- ⚠Results require interpretation by a genetic counselor
- ⚠Does not replace clinical diagnosis
- ⚠Limited to known genetic variants in databases
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Psychological impact of genetic results
Interfering Factors
- ●Sample contamination
- ●Degraded DNA quality
- ●Recent blood transfusion
- ●Hemolyzed sample
Compare With Similar Tests
| Test | ADAMTS13 Gene Thrombotic thrombocytopenic purpura NGS Genetic Test | ADAMTS13 Activity Assay | von Willebrand Factor Test | Complete Blood Count |
|---|---|---|---|---|
| Comparison | ADAMTS13 Gene Thrombotic thrombocytopenic purpura NGS Genetic Test |
Frequently Asked Questions
What is the ADAMTS13 Gene NGS Genetic Test?
Who should get this test?
How much does the test cost?
What sample is required for the test?
Is home sample collection available?
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Is genetic counseling included?
Are there any risks associated with the test?
Can this test diagnose acquired TTP?
Is the test covered by insurance?
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