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DNA Labs India

AFP (Alpha Fetoprotein): Maternal Test

DNA Labs India | ISO 9001:2015 Certified

AFP (Alpha Fetoprotein): Maternal Test

Short Name: AFP Maternal Test

Also known as: Alpha-Fetoprotein Test, AFP Screening, Maternal AFP Test

AFP (Alpha Fetoprotein): Maternal Test test available at DNA Labs India for ₹936. Uses Chemiluminescent Immunoassay on Serum samples. Results in Results are typically available within 24 hours of sample receipt at the lab.. Free home collection in 300+ cities across India.

Screening TestFemaleAdult, Pregnant🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of the AFP Maternal Test is to screen for fetal abnormalities, particularly neural tube defects and Down syndrome, during the second trimester of pregnancy. It helps identify pregnancies at higher risk, enabling further diagnostic testing if needed.

Test Code
75
Price
₹936
Sample Type
Serum
Result Time
Results are typically available within 24 hours of sample receipt at the lab.
Fasting Required
No
Method
Chemiluminescent Immunoassay
Step 1

Sample Collection

No special preparation is required, but ensure the test is scheduled within the recommended gestational age window of 14 to 22 weeks. Inform your healthcare provider about any medications or health conditions.

Method: Venipuncture

Step 2

Laboratory Analysis

A healthcare professional will draw a small blood sample from a vein in your arm. The procedure is quick and typically involves minimal discomfort.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bleeding. You can resume normal activities immediately. Results will be processed and delivered as per the report delivery methods.

Timeline: Results are typically available within 24 hours of sample receipt at the lab.

Patient Instructions

1
Before the Test:Confirm the test is scheduled between 14-22 weeks of pregnancy. No fasting is required.
2
During the Test:A blood sample is drawn from the mother's arm in a clinical or home setting.
3
After the Test:The sample is analyzed, and results are reported. Follow up with your doctor to discuss outcomes.

About This Test

Who Should Get This Test

The purpose of the AFP Maternal Test is to screen for fetal abnormalities, particularly neural tube defects and Down syndrome, during the second trimester of pregnancy. It helps identify pregnancies at higher risk, enabling further diagnostic testing if needed.

How to Prepare

  • Schedule the test between 14 and 22 weeks of pregnancy.
  • Provide accurate gestational age information to the lab.
  • Ensure the blood sample is collected in an SST tube and shipped refrigerated or frozen as specified.

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"The AFP test is a vital prenatal screening tool to assess the risk of neural tube defects and Down syndrome. Consult your gynecologist for personalized advice based on your pregnancy history."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (0.5 mL min.)
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature
Refrigerator (2-8°C)
Frozen (-20°C)
Sample Rejection Criteria:
  • Hemolyzed or lipemic samples
  • Samples collected outside the recommended gestational age
  • Insufficient sample volume
  • Incorrect tube type or labeling errors

Understanding Your Results

AFP levels are interpreted based on gestational age, maternal weight, and other factors. Results are often reported as multiples of the median (MoM). Consult your healthcare provider for a comprehensive interpretation.
📊

Level: High AFP

📊

Level: Low AFP

📊

Level: Normal AFP

⚠️ When to Consult a Doctor:

If your AFP test results are abnormal or if you have risk factors for birth defects, consult your obstetrician or genetic counselor for further evaluation and possible diagnostic testing.

Limitations

  • This is a screening test, not a diagnostic test; abnormal results require confirmatory testing.
  • False positives and false negatives can occur.
  • It does not detect all birth defects or genetic conditions.
  • Results should be interpreted in conjunction with other prenatal tests and clinical findings.

Risks & Considerations

  • Minimal risks associated with blood draw, such as slight pain, bruising, or infection at the puncture site.
  • False results may lead to unnecessary anxiety or further invasive testing.

Interfering Factors

  • Multiple pregnancies (e.g., twins or triplets)
  • Incorrect gestational age calculation
  • Maternal weight
  • Certain maternal health conditions like liver disease
  • Laboratory sample handling errors

Compare With Similar Tests

TestAFP (Alpha Fetoprotein): Maternal TestTriple Marker TestQuad Marker TestUltrasoundAmniocentesis
ComparisonAFP (Alpha Fetoprotein): Maternal TestIncludes AFP along with hCG and estriol for broader screening.Adds inhibin A to the triple marker for improved detection rates.Provides imaging to detect structural anomalies, often used alongside blood tests.Diagnostic test that analyzes fetal cells for genetic disorders, usually after abnormal screening.

Frequently Asked Questions

What is the AFP Maternal Test?
The AFP Maternal Test is a blood screening test that measures alpha-fetoprotein levels in pregnant women to assess the risk of neural tube defects and Down syndrome in the fetus.
When should I take the AFP test during pregnancy?
The test is recommended between 14 and 22 weeks of pregnancy, ideally during the second trimester for optimal accuracy.
How is the AFP test performed?
It involves a simple blood draw from the mother's arm. The sample is then analyzed in a lab using chemiluminescent immunoassay.
What do high AFP levels indicate?
High AFP levels may suggest neural tube defects like spina bifida, multiple pregnancies, or incorrect gestational age dating, requiring further evaluation.
What do low AFP levels indicate?
Low AFP levels may be associated with an increased risk of Down syndrome or other chromosomal abnormalities, but confirmatory tests are needed.
Is the AFP test mandatory during pregnancy?
It is not mandatory but is a standard screening test recommended for all pregnant women to help identify potential risks early.
What is the cost of the AFP test at DNA Labs India?
The test costs INR 936, with free home sample collection available across India.
Is home collection available for the AFP test?
Yes, DNA Labs India offers free home sample collection for online bookings in numerous cities.
How long does it take to get AFP test results?
Results are typically delivered within 24 hours via online portal, email, or WhatsApp.
Are there any risks or side effects of the AFP test?
The test is safe with minimal risks, such as slight discomfort during blood draw. Abnormal results may require further testing.
Can diet or medications affect AFP levels?
Generally, AFP levels are not significantly affected by diet or medications, but always inform your healthcare provider about any substances you take.
What should I do if my AFP test results are abnormal?
Consult your obstetrician or genetic counselor immediately. They may recommend additional tests like ultrasound or amniocentesis for confirmation.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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