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DNA Labs India

APC Gene Desmoid disease, hereditary NGS Genetic Test

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APC Gene Desmoid disease, hereditary NGS Genetic Test

Also known as: APC Gene Mutation Test, Hereditary Desmoid Disease Genetic Test

APC Gene Desmoid disease, hereditary NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The purpose of this test is to identify mutations in the APC gene that increase the risk of hereditary desmoid disease, enabling early detection, genetic counseling, and informed decision-making for patients and families.

Test Code
2864
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No specific preparation required. Ensure to provide clinical history and undergo genetic counseling as advised.

Method: Blood draw

Step 2

Laboratory Analysis

A blood sample will be drawn by a trained phlebotomist. For FTA card, a drop of blood is applied.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Resume normal activities unless otherwise directed.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Undergo genetic counseling to understand the test implications and provide informed consent.
2
During the Test:Sample collection via blood draw or FTA card; minimal discomfort expected.
3
After the Test:Wait for results (3-4 weeks) and schedule a follow-up with a genetic counselor or physician for interpretation.

About This Test

Who Should Get This Test

The purpose of this test is to identify mutations in the APC gene that increase the risk of hereditary desmoid disease, enabling early detection, genetic counseling, and informed decision-making for patients and families.

How to Prepare

  • Provide accurate clinical and family history
  • Follow any pre-test instructions from the genetic counselor
  • Ensure sample is collected in a sterile environment
  • Label the sample correctly with patient details

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This test is crucial for early detection and management of hereditary desmoid disease, helping in personalized treatment planning."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodBlood draw

Sample Stability

Blood samples stable at room temperature for 24 hours
Extracted DNA stable at -20°C for long-term storage
Sample Rejection Criteria:
  • Insufficient sample volume
  • Contaminated or hemolyzed sample
  • Incorrect labeling

Understanding Your Results

Results from the APC Gene Desmoid Disease Hereditary NGS Genetic Test indicate the presence or absence of mutations in the APC gene. A positive result suggests an increased risk for hereditary desmoid disease, while a negative result may reduce risk but does not eliminate it entirely.
📊

Positive for pathogenic variant

High risk for hereditary desmoid disease; recommend genetic counseling and surveillance.

📊

Negative for pathogenic variant

Reduced risk, but clinical correlation and family history should be considered.

📊

Variant of uncertain significance (VUS)

Further testing and family studies may be needed for clarification.

⚠️ When to Consult a Doctor:

Consult a doctor if you have a family history of desmoid tumors, experience symptoms like persistent pain or swelling, or receive a positive test result for further management and genetic counseling.

Limitations

  • ⚠May not detect all types of APC gene mutations
  • ⚠Results require interpretation by a genetic counselor
  • ⚠Does not replace clinical diagnosis

Risks & Considerations

  • ●Minor bruising or discomfort at the blood draw site
  • ●Emotional impact of genetic results
  • ●Risk of false positives or negatives

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA quality
  • ●Recent blood transfusions

Frequently Asked Questions

What is the APC Gene Desmoid Disease Hereditary NGS Genetic Test?
This test uses Next-Generation Sequencing to detect mutations in the APC gene associated with hereditary desmoid disease, a condition causing non-cancerous tumors in connective tissues.
Why is this test recommended?
It is recommended for individuals with a family history of desmoid tumors or symptoms like pain and swelling, to assess genetic risk and guide healthcare decisions.
How is the test performed?
A blood sample or DNA extract is analyzed using NGS technology to identify mutations in the APC gene.
What does a positive result mean?
A positive result indicates a mutation in the APC gene, increasing the risk for hereditary desmoid disease, and may require further monitoring or genetic counseling.
What are the risks of the test?
Risks are minimal, including slight discomfort from blood draw and potential emotional impact of results.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is the test covered by insurance?
Coverage varies; check with your insurance provider. DNA Labs India offers the test at INR 20000 with home collection options.
Can I get home sample collection?
Yes, DNA Labs India provides free home sample collection for this test across many cities in India.
What should I do before the test?
Undergo genetic counseling, provide clinical history, and follow any specific instructions from your healthcare provider.
How accurate is the test?
The test uses advanced NGS technology with high accuracy, but results should be interpreted by a qualified genetic counselor.
What are desmoid tumors?
Desmoid tumors are rare, non-cancerous growths in connective tissues that can cause pain, swelling, and restricted movement.
How can I interpret my results?
Consult a genetic counselor or physician who can explain the results in the context of your medical and family history.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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