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DNA Labs India

T-Cell Gene Rearrangement Mutation Detection Test

DNA Labs India | ISO 9001:2015 Certified

T-Cell Gene Rearrangement Mutation Detection Test

Short Name: T-Cell Gene Rearrangement Test

Also known as: T-Cell Receptor Gene Rearrangement Test, TCR Gene Rearrangement Mutation Test

T-Cell Gene Rearrangement Mutation Detection Test test available at DNA Labs India for ₹20,000. Uses PCR on Whole blood samples. Results in 15 working days. Free home collection in 300+ cities across India.

Molecular Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

This assay is useful to diagnose a lymphoma, monitor the progress of treatment of lymphoma, and measure minimal residual disease (MRD), which can predict the likelihood of recurrence.

Test Code
42
Price
₹20,000
Sample Type
Whole blood
Result Time
15 working days
Fasting Required
No
Method
PCR
Step 1

Sample Collection

Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.

Method: Venipuncture

Step 2

Laboratory Analysis

Standard venipuncture procedure to collect 4 mL of whole blood in an EDTA tube.

Step 3

Report Delivery

Ship refrigerated. DO NOT FREEZE.

Timeline: 15 working days

Patient Instructions

1
Before the Test:Ensure the Genomics Clinical Information Requisition Form (Form 20) is filled and submitted.
2
During the Test:Blood sample collection via venipuncture.
3
After the Test:Sample shipped refrigerated for analysis; results delivered within 15 working days.

About This Test

Who Should Get This Test

This assay is useful to diagnose a lymphoma, monitor the progress of treatment of lymphoma, and measure minimal residual disease (MRD), which can predict the likelihood of recurrence.

How to Prepare

  • Collect 4 mL whole blood in a lavender top (EDTA) tube
  • Ensure proper labeling and fill the Genomics Clinical Information Requisition Form (Form 20)
  • Ship sample refrigerated; do not freeze

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This test is crucial for diagnosing T-cell lymphomas, monitoring treatment response, and assessing minimal residual disease to guide therapeutic decisions."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole blood
Sample Volume4 mL (2 mL min.)
ContainerLavender top (EDTA) tube
Collection MethodVenipuncture

Sample Stability

Room Temperature
Refrigerator
Frozen
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Incorrect tube type
  • Missing or incomplete Genomics Clinical Information Requisition Form (Form 20)
  • Sample not shipped refrigerated

Understanding Your Results

Results indicate the presence or absence of T-cell gene rearrangements. A positive result suggests clonal expansion, which may be associated with malignancy or autoimmune conditions.
📊

Detected

Indicates clonal T-cell proliferation; further clinical correlation is needed for diagnosis of lymphoma or autoimmune disease.

📊

Not Detected

Suggests no clonal rearrangement; but clinical context should be considered, as some conditions may not be detected.

⚠️ When to Consult a Doctor:

If symptoms such as swollen lymph nodes, fatigue, night sweats, weight loss, joint pain, or skin rashes persist, or if test results are abnormal.

Limitations

  • ⚠May not detect all mutations or variants
  • ⚠False positives or negatives can occur
  • ⚠Specific to T-cell disorders; not comprehensive for all cancers

Risks & Considerations

  • ●Minor bruising or pain at the blood draw site
  • ●Rare risk of infection or dizziness

Interfering Factors

  • ●Sample contamination
  • ●Improper storage or shipping temperature
  • ●Hemolyzed or lipemic samples

Compare With Similar Tests

TestT-Cell Gene Rearrangement Mutation Detection TestB-Cell Gene Rearrangement TestFlow CytometryAutoimmune Disease Panel
ComparisonT-Cell Gene Rearrangement Mutation Detection Test

Frequently Asked Questions

What is the T-Cell Gene Rearrangement Mutation Detection Test?
It is a genetic test that detects mutations in T-cell genes, helping diagnose cancers like T-cell lymphomas and autoimmune diseases.
Why is this test important?
It aids in diagnosing specific cancers and autoimmune conditions, monitoring treatment, and predicting disease recurrence.
How is the test performed?
Using PCR on a blood or tissue sample to identify gene rearrangements or mutations.
What sample is required?
4 mL of whole blood in an EDTA tube, shipped refrigerated.
Is fasting required for the test?
No, fasting is not required, but a duly filled requisition form is mandatory.
How long does it take to get results?
Results are typically available within 15 working days.
What does a positive result mean?
It indicates clonal T-cell expansion, which may suggest lymphoma or autoimmune disease; clinical correlation is needed.
What are the risks of the test?
Risks are minimal, such as bruising from blood draw, and are generally rare.
Is the test covered by insurance?
Coverage varies by insurance plan; it is not universally covered. Check with your provider.
Can this test diagnose autoimmune diseases?
Yes, it can help diagnose autoimmune diseases like lupus and rheumatoid arthritis by detecting relevant gene mutations.
How accurate is the test?
The test is highly accurate for detecting specific mutations, but false positives or negatives can occur; interpret with clinical context.
Where can I get this test done?
At DNA Labs India, with free home sample collection available in numerous cities across India.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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