BRAF Mutation Analysis (V600E) Test
Short Name: BRAF V600E
Also known as: BRAF V600E Mutation Test, BRAF Gene Mutation Analysis
BRAF Mutation Analysis (V600E) Test test available at DNA Labs India for ₹9,000. Uses Sanger Sequencing on Tumor tissue samples. Results in 7-8 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of BRAF Mutation Analysis (V600E) is to identify the presence of the BRAF V600E mutation in cancerous tissues, which helps in diagnosing specific cancer types, predicting response to targeted therapies, and guiding personalized treatment strategies for improved patient outcomes.
- Test Code
- 2955
- Price
- ₹9,000
- Sample Type
- Tumor tissue
- Result Time
- 7-8 days
- Fasting Required
- No
- Method
- Sanger Sequencing
Sample Collection
A doctor's prescription is required for BRAF Mutation Analysis (V600E). Prescription is not applicable for surgery, pregnancy cases, or people planning to travel abroad. Ensure all patient details are accurately provided.
Method: Biopsy or surgical sample
Laboratory Analysis
Sample collection involves obtaining a tumor tissue biopsy or surgical specimen under sterile conditions by a qualified healthcare professional.
Report Delivery
The sample is preserved and sent to the laboratory for analysis. Patients may experience minor discomfort at the biopsy site, which typically resolves quickly.
Timeline: 7-8 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of BRAF Mutation Analysis (V600E) is to identify the presence of the BRAF V600E mutation in cancerous tissues, which helps in diagnosing specific cancer types, predicting response to targeted therapies, and guiding personalized treatment strategies for improved patient outcomes.
How to Prepare
- Collect tumor tissue sample via biopsy or surgical excision
- Use appropriate containers and fixatives as per laboratory guidelines
- Label the sample with patient details and test information
- Transport the sample at ambient temperature to the laboratory
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early detection of BRAF mutations can guide targeted therapy and improve patient outcomes in various cancers, including melanoma and thyroid cancer."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient or non-representative tumor tissue
- Sample contamination or improper labeling
- Missing doctor's prescription where required
Understanding Your Results
Detected
BRAF V600E mutation is present, indicating potential eligibility for targeted therapies like BRAF inhibitors.
Action: Consult with an oncologist for personalized treatment planning.
Not Detected
BRAF V600E mutation is not found in the sample. Other genetic tests may be considered.
Action: Discuss alternative diagnostic or treatment options with your doctor.
Consult a doctor if you have symptoms such as new or changing moles, skin lesions that bleed or itch, persistent cough, chest pain, or a family history of cancer. Early consultation can facilitate timely testing and treatment.
Limitations
- ⚠Test only detects the V600E mutation; other BRAF mutations may not be identified
- ⚠Results are dependent on the quality and representativeness of the tumor sample
- ⚠False negatives may occur if tumor heterogeneity is present
Risks & Considerations
- ●Minor pain or bleeding at the biopsy site
- ●Risk of infection, though rare with proper sterile techniques
- ●Possible need for repeat sampling if initial sample is inadequate
Interfering Factors
- ●Poor sample quality or insufficient tissue
- ●Contamination during sample collection or processing
- ●Use of certain fixatives that may affect DNA integrity
Frequently Asked Questions
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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