CALR Mutation Analysis (Deletion or Insertion in Exon 9) Test
Short Name: CALR Mutation Analysis
Also known as: CALR Gene Mutation Analysis, Calreticulin Mutation Test
CALR Mutation Analysis (Deletion or Insertion in Exon 9) Test test available at DNA Labs India for ₹9,000. Uses Sanger Sequencing on Bone Marrow/Peripheral Blood samples. Results in 7-8 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of CALR Mutation Analysis is to diagnose CALR gene mutations associated with myeloproliferative neoplasms (MPNs), aiding in the identification and management of these blood disorders.
- Test Code
- 2957
- Price
- ₹9,000
- Sample Type
- Bone Marrow/Peripheral Blood
- Result Time
- 7-8 days
- Fasting Required
- No
- Method
- Sanger Sequencing
Sample Collection
A doctor's prescription is required, except for surgery, pregnancy, or travel abroad cases. Ensure sample is kept cool with a cool pack.
Method: Blood draw or bone marrow aspiration
Laboratory Analysis
Sample collected via venipuncture for peripheral blood or bone marrow aspiration, using an EDTA vacutainer (2ml).
Report Delivery
Apply pressure to the collection site to prevent bruising. Sample is transported to the lab under cool conditions.
Timeline: 7-8 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of CALR Mutation Analysis is to diagnose CALR gene mutations associated with myeloproliferative neoplasms (MPNs), aiding in the identification and management of these blood disorders.
How to Prepare
- Use EDTA vacutainer (2ml)
- Keep sample cool with a cool pack
- Label sample correctly with patient details
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is crucial for diagnosing CALR mutations in myeloproliferative neoplasms, helping guide treatment decisions for patients with symptoms like fatigue and splenomegaly."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Incorrect sample type or container
- Missing patient information
Understanding Your Results
Mutation detected
Indicates CALR mutation, supporting diagnosis of MPN. Further tests needed to confirm specific MPN type and guide treatment.
Mutation not detected
No CALR mutation in exon 9. Consider other genetic tests or clinical evaluation if MPN symptoms persist.
Consult a doctor if you experience symptoms of MPNs such as fatigue, shortness of breath, or enlarged spleen, or if you have a family history of these disorders. Discuss test results with a healthcare provider for appropriate management.
Limitations
- ⚠Test only detects mutations in exon 9 of CALR gene
- ⚠May not identify all genetic variants associated with MPNs
Risks & Considerations
- ●Minor bruising or discomfort at the collection site
- ●Rare risk of infection from bone marrow aspiration
Interfering Factors
- ●Sample contamination
- ●Improper sample storage or handling
Frequently Asked Questions
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