CCND1 Gene Colorectal cancer, hereditary, susceptibility to NGS Genetic Test
Short Name: CCND1 Colorectal Cancer NGS Test
Also known as: Cyclin D1 Gene Test, Hereditary Colorectal Cancer Genetic Test, CCND1 Mutation Analysis
CCND1 Gene Colorectal cancer, hereditary, susceptibility to NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify mutations in the CCND1 gene and other associated genes to assess hereditary susceptibility to colorectal cancer, enabling early intervention and personalized management.
- Test Code
- 2861
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No special preparation required. Provide clinical history and family pedigree during genetic counseling.
Method: Venipuncture or Fingerstick
Laboratory Analysis
Blood sample collected via venipuncture or fingerstick. For FTA card, a drop of blood is applied.
Report Delivery
Apply pressure to the puncture site. Store sample as per instructions. Await report in 3-4 weeks.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify mutations in the CCND1 gene and other associated genes to assess hereditary susceptibility to colorectal cancer, enabling early intervention and personalized management.
How to Prepare
- Ensure patient identification and consent
- Use sterile equipment for blood collection
- Label samples correctly
- Transport samples at ambient temperature
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for CCND1 mutations can help identify individuals at increased risk for hereditary colorectal cancer, enabling proactive screening and management. Consultation with a genetic counselor is recommended for result interpretation."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Insufficient sample volume
- Incorrect labeling or missing documentation
Understanding Your Results
Positive for pathogenic variant
Increased risk for hereditary colorectal cancer. Recommend genetic counseling, enhanced screening, and family testing.
Negative for pathogenic variants
No mutations detected in CCND1 gene. Risk may be due to other factors; continue routine screening.
Variant of uncertain significance (VUS)
Clinical significance unclear. Recommend follow-up testing and genetic counseling.
Consult a doctor if results indicate high risk, if symptoms develop, or for personalized screening recommendations based on family history.
Limitations
- ⚠Test may not detect all genetic mutations
- ⚠Results require clinical correlation and genetic counseling
- ⚠Does not replace routine colorectal cancer screening
- ⚠Limited to known variants in the CCND1 gene
Risks & Considerations
- ●Minimal risk from blood draw (bruising, infection)
- ●Psychological impact of genetic results
- ●Potential for insurance or discrimination issues (consult genetic counselor)
Interfering Factors
- ●Poor sample quality or contamination
- ●Hemolyzed blood sample
- ●Recent blood transfusion
- ●Technical errors in sequencing
Compare With Similar Tests
| Test | CCND1 Gene Colorectal cancer, hereditary, susceptibility to NGS Genetic Test | Lynch Syndrome Gene Panel | APC Gene Test | MUTYH Gene Test | Comprehensive Colorectal Cancer Panel |
|---|---|---|---|---|---|
| Comparison | CCND1 Gene Colorectal cancer, hereditary, susceptibility to NGS Genetic Test |
Frequently Asked Questions
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