CD59 Gene Hemolytic anemia, CD59-mediated, with or without immune-mediated polyneuropathy NGS Genetic Test
Also known as: CD59 Gene Mutation Test, CD59-mediated Hemolytic Anemia Test, CD59 Deficiency Genetic Test
CD59 Gene Hemolytic anemia, CD59-mediated, with or without immune-mediated polyneuropathy NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 3, 2026
Overview
The purpose of the CD59 Gene NGS Genetic Test is to identify mutations in the CD59 gene that may lead to CD59-mediated hemolytic anemia and/or immune-mediated polyneuropathy. This test aids in confirming a clinical diagnosis, guiding treatment strategies, and providing information for genetic counseling and family planning.
- Test Code
- 5588
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
No specific preparation is required. Ensure genetic counseling is completed and clinical history is provided.
Laboratory Analysis
A blood sample will be collected by a trained phlebotomist. For FTA card, a drop of blood is applied.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Store samples as instructed.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the CD59 Gene NGS Genetic Test is to identify mutations in the CD59 gene that may lead to CD59-mediated hemolytic anemia and/or immune-mediated polyneuropathy. This test aids in confirming a clinical diagnosis, guiding treatment strategies, and providing information for genetic counseling and family planning.
How to Prepare
- Use sterile equipment for blood collection
- Label samples correctly with patient details
- Transport samples at ambient room temperature
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Early genetic testing for CD59 mutations can guide treatment and improve outcomes for patients with hemolytic anemia and polyneuropathy."
Last medically reviewed: September 3, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or contaminated samples
- Insufficient sample volume
- Incorrectly labeled samples
Understanding Your Results
Positive for pathogenic variants
Confirms genetic predisposition to CD59-mediated hemolytic anemia and/or polyneuropathy. Further clinical evaluation and management are recommended.
Negative for pathogenic variants
No mutations detected in the CD59 gene. Clinical correlation is advised if symptoms persist.
Variant of uncertain significance (VUS)
A genetic variant was found but its clinical significance is unknown. Genetic counseling and follow-up testing may be needed.
Consult a doctor if you experience symptoms of hemolytic anemia (e.g., fatigue, jaundice) or polyneuropathy (e.g., numbness, weakness), have a family history of CD59-related disorders, or after receiving test results for appropriate management.
Limitations
- ⚠This test may not detect all possible mutations in the CD59 gene
- ⚠Results require interpretation by a qualified geneticist or healthcare provider
- ⚠Genetic testing has limitations in predicting disease severity or onset
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Psychological impact of genetic test results
- ●Potential for inconclusive results requiring further testing
Interfering Factors
- ●Sample contamination during collection or processing
- ●Degraded DNA quality due to improper storage
- ●Recent blood transfusions may affect genetic analysis
Frequently Asked Questions
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