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CDKN2A Gene Pancreatic cancer/melanoma syndrome, familial NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

CDKN2A Gene Pancreatic cancer/melanoma syndrome, familial NGS Genetic Test

Also known as: CDKN2A Gene Mutation Test, Familial Atypical Multiple Mole Melanoma (FAMMM) Syndrome Test

CDKN2A Gene Pancreatic cancer/melanoma syndrome, familial NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

Next-Generation Sequencing (NGS)🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The purpose of the CDKN2A Gene Pancreatic Cancer/Melanoma Syndrome NGS Genetic Test is to identify mutations in the CDKN2A gene that increase the risk of developing familial pancreatic cancer and melanoma. This test enables early detection, facilitates genetic counseling, and guides personalized screening and prevention strategies for at-risk individuals and their families.

Test Code
2922
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Clinical history of the patient, including family history of pancreatic cancer and melanoma, is required. A genetic counseling session is recommended to draw a pedigree chart of affected family members and discuss test implications.

Step 2

Laboratory Analysis

Your sample is analyzed using Next-Generation Sequencing (NGS) in our laboratory.

Step 3

Report Delivery

A certified pathologist reviews and signs your report. You receive it as a secure PDF via email and WhatsApp.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Provide detailed clinical and family history. Attend a genetic counseling session to understand the test's implications and draw a family pedigree chart.
2
During the Test:A blood sample will be collected via venipuncture, or an alternative sample type as specified.
3
After the Test:Results will be available in 3 to 4 weeks. Follow up with a healthcare provider or genetic counselor to discuss results and next steps.

About This Test

Who Should Get This Test

The purpose of the CDKN2A Gene Pancreatic Cancer/Melanoma Syndrome NGS Genetic Test is to identify mutations in the CDKN2A gene that increase the risk of developing familial pancreatic cancer and melanoma. This test enables early detection, facilitates genetic counseling, and guides personalized screening and prevention strategies for at-risk individuals and their families.

How to Prepare

  • Blood sample collection by venipuncture
  • Alternatively, extracted DNA or one drop of blood on an FTA card can be used
  • Ensure proper labeling and handling of samples

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card

Understanding Your Results

Results from the CDKN2A Gene NGS Genetic Test indicate the presence or absence of mutations in the CDKN2A gene. A positive result suggests an increased risk for familial pancreatic cancer and melanoma, necessitating further clinical evaluation and surveillance. A negative result may reduce risk but does not eliminate it entirely, especially if there is a strong family history.
📊

Positive for CDKN2A mutation

Increased risk for pancreatic cancer and melanoma. Recommend enhanced screening, genetic counseling, and discussion of risk-reduction strategies.

📊

Negative for CDKN2A mutation

No mutation detected, but risk may still be present based on family history. Continue standard screening and consult with a healthcare provider.

📊

Variant of uncertain significance (VUS)

Genetic change identified but clinical significance unknown. Further testing and family studies may be needed. Genetic counseling is advised.

⚠️ When to Consult a Doctor:

Consult a doctor if you have a family history of pancreatic cancer or melanoma, experience symptoms such as jaundice, abdominal pain, or unusual skin changes, or if you receive a positive or uncertain genetic test result for guidance on screening and management.

Risks & Considerations

  • ●Minimal risk associated with blood collection, such as slight pain, bruising, or infection at the site.

Frequently Asked Questions

What is the CDKN2A Gene Pancreatic Cancer/Melanoma Syndrome?
It is a hereditary condition caused by mutations in the CDKN2A gene, which increases the risk of developing pancreatic cancer and melanoma, often running in families.
Who should consider this genetic test?
Individuals with a family history of pancreatic cancer, melanoma, or both, especially if multiple family members are affected or if cancers occurred at a young age.
What are the symptoms of this syndrome?
Symptoms for pancreatic cancer include jaundice, abdominal pain, weight loss, loss of appetite, and fatigue. For melanoma, look for new or changing moles with asymmetrical shapes, irregular borders, or bleeding.
How is the test performed?
The test uses Next-Generation Sequencing (NGS) to analyze the CDKN2A gene from a blood sample, extracted DNA, or a blood drop on an FTA card.
What is the cost of the test?
The cost is INR 20,000, which includes home sample collection across India at a discounted price.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home sample collection available?
Yes, free home sample collection is offered for online bookings in numerous cities across India.
What does a positive result mean?
A positive result indicates a mutation in the CDKN2A gene, increasing the risk for pancreatic cancer and melanoma. It warrants enhanced screening and genetic counseling.
What are the risks of the test?
The test involves minimal risks, primarily related to blood draw, such as slight pain or bruising. There are no significant health risks from the genetic analysis itself.
Can this test be done for children?
Yes, the test can be performed on individuals of all ages, but genetic counseling is recommended to discuss implications, especially for minors.
Is genetic counseling required before the test?
While not mandatory, genetic counseling is highly recommended to understand the test's purpose, interpret results, and discuss family risk assessment.
How accurate is the NGS genetic test?
NGS is a highly accurate method for detecting genetic mutations, but accuracy depends on sample quality and laboratory standards. DNA Labs India ensures reliable results with accredited testing.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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