Chlamydophila Pneumoniae IgG Test
Short Name: C. Pneumoniae IgG
Also known as: C. pneumoniae IgG Antibody Test, Chlamydia pneumoniae IgG Test, Chlamydophila pneumoniae Serology, CP IgG Serology
Chlamydophila Pneumoniae IgG Test test available at DNA Labs India for ₹831. Uses Enzyme Immunoassay (EIA) on Serum samples. Results in Results are typically available within 1 week. Reports will be delivered via the online portal, email, or WhatsApp.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Kothari Ramesh Shantilal
Consultant Microbiologist · Reg: 27670
Last reviewed: September 7, 2026
Overview
The primary purpose of the Chlamydophila pneumoniae IgG test is to determine whether an individual has been exposed to C. pneumoniae at some point in the past. This test helps physicians assess the immune response to the bacterium, differentiate between atypical pneumonia-causing pathogens, and evaluate patients with chronic or recurrent respiratory symptoms. It is particularly useful when clinical presentation is suggestive of an atypical respiratory infection but the causative agent is unclear. The test may also be used in epidemiological studies and in research settings to understand the seroprevalence of C. pneumoniae in a population.
- Test Code
- 14
- CPT Code
- 86638
- ICD Code
- J16.0
- Price
- ₹831
- Sample Type
- Serum
- Result Time
- Results are typically available within 1 week. Reports will be delivered via the online portal, email, or WhatsApp.
- Fasting Required
- No
- Method
- Enzyme Immunoassay (EIA)
Sample Collection
No fasting or special preparation is required. Inform your healthcare provider about any medications, recent vaccinations, or immunoglobulin treatments.
Method: Venipuncture
Laboratory Analysis
A trained phlebotomist will collect approximately 3 mL of venous blood from a vein in your arm into a Serum Separator Tube (SST). The procedure typically takes 3 to 5 minutes.
Report Delivery
Apply gentle pressure on the puncture site with cotton for 3–5 minutes. A small bruise may develop, which is normal. Avoid strenuous activity with the affected arm for a few hours.
Timeline: Results are typically available within 1 week. Reports will be delivered via the online portal, email, or WhatsApp.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the Chlamydophila pneumoniae IgG test is to determine whether an individual has been exposed to C. pneumoniae at some point in the past. This test helps physicians assess the immune response to the bacterium, differentiate between atypical pneumonia-causing pathogens, and evaluate patients with chronic or recurrent respiratory symptoms. It is particularly useful when clinical presentation is suggestive of an atypical respiratory infection but the causative agent is unclear. The test may also be used in epidemiological studies and in research settings to understand the seroprevalence of C. pneumoniae in a population.
How to Prepare
- No fasting is required before sample collection
- Wear a short-sleeved or loose-fitting shirt for easy arm access
- Inform the phlebotomist if you have a history of fainting during blood draws
- Stay hydrated by drinking water before the test
- Avoid heavy exercise immediately before the sample collection
Doctor's Notes
Reviewed by Dr Kothari Ramesh Shantilal — MBBS, MD (Microbiology) · Reg. No. 27670
"Chlamydophila pneumoniae is an atypical respiratory pathogen that often causes mild upper respiratory tract infections but can progress to pneumonia, bronchitis, and pharyngitis. An IgG-positive result indicates past exposure and does not confirm an active infection. In clinical practice, I recommend pairing this test with an IgM antibody test and correlating with clinical symptoms and radiological findings for accurate diagnosis. A four-fold rise in IgG titres between acute and convalescent samples collected 2–3 weeks apart is considered more diagnostically significant than a single positive result. Patients with persistent cough, atypical pneumonia, or unresponsive respiratory symptoms should discuss IgG testing with their physician."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed, lipemic, or contaminated serum samples
- Samples not collected in a Serum Separator Tube (SST)
- Specimens received beyond the acceptable stability window
- Insufficient sample volume (less than 1.5 mL serum)
- Unlabelled or mislabelled samples
Understanding Your Results
Negative (< 0.9 IV)
No detectable IgG antibodies against C. pneumoniae. This suggests no prior exposure or infection occurred too recently for IgG to develop. If clinical suspicion is high, repeat testing in 2–3 weeks or order an IgM test.
Equivocal (0.9 – 1.1 IV)
Borderline antibody levels. A repeat test in 2–3 weeks is recommended to determine if titres are rising or falling. Clinical correlation is essential.
Positive (> 1.1 IV)
IgG antibodies are detected, indicating past exposure to C. pneumoniae. This does not confirm active infection. For confirmation of recent infection, paired sera testing with a convalescent sample 2–4 weeks later is recommended to check for a four-fold rise in titre.
Consult your doctor if you have a persistent cough lasting more than 2 weeks, unexplained fever, chest pain, shortness of breath, or if your IgG result is positive and you are experiencing active respiratory symptoms. Your physician may recommend additional testing such as Chlamydophila pneumoniae IgM, PCR testing, or a chest X-ray to confirm a diagnosis.
Limitations
- ⚠A single positive IgG result cannot distinguish between a past resolved infection and a current active infection
- ⚠Cannot determine the exact timing of infection based on a single titre
- ⚠Seroconversion timelines vary between individuals; some patients may take longer to develop detectable IgG
- ⚠Cross-reactivity with other Chlamydiaceae family members may reduce specificity
- ⚠This test should be interpreted alongside clinical symptoms, radiological findings, and IgM testing for a comprehensive diagnosis
Risks & Considerations
- ●Minor bruising or pain at the venipuncture site
- ●Lightheadedness or fainting in individuals sensitive to blood draws
- ●Very rare risk of infection at the puncture site
- ●Extremely rare risk of excessive bleeding in individuals with bleeding disorders
Interfering Factors
- ●Cross-reactivity with IgG antibodies from other Chlamydia species (e.g., C. trachomatis, C. psittaci) may produce false-positive results
- ●Immunocompromised patients may show reduced or absent antibody responses leading to false-negative results
- ●Recent blood transfusions or immunoglobulin therapy may interfere with antibody levels
- ●Early-stage infection (within the first 2–4 weeks) may yield false-negative results as IgG has not yet developed
- ●Hemolytic or lipemic serum samples may affect assay accuracy
Compare With Similar Tests
| Test | Chlamydophila Pneumoniae IgG Test | Chlamydophila Pneumoniae IgM Test | Chlamydophila Pneumoniae IgA Test | Chlamydophila pneumoniae PCR Test | Mycoplasma pneumoniae IgG Test |
|---|---|---|---|---|---|
| Comparison | Chlamydophila Pneumoniae IgG Test | IgM antibodies appear earlier in infection (within 1–2 weeks) and suggest a recent or active primary infection. IgG appears later and indicates past exposure. Both tests are complementary for diagnosis. | IgA testing may indicate persistent or chronic infection, especially in respiratory conditions. IgG alone may not distinguish between resolved and ongoing infection. | PCR detects the genetic material of the bacterium directly from respiratory samples and confirms active infection. IgG serology detects immune response and past exposure. PCR is more specific for current infection. | Mycoplasma pneumoniae is another atypical respiratory pathogen with similar symptoms. Both tests help differentiate the causative agent in atypical pneumonia cases. |
Frequently Asked Questions
What is a Chlamydophila Pneumoniae IgG test?
What does a positive Chlamydophila pneumoniae IgG result mean?
What does a negative Chlamydophila pneumoniae IgG result mean?
Is fasting required for the Chlamydophila pneumoniae IgG test?
How is the sample collected for this test?
How long does it take to get the Chlamydophila pneumoniae IgG test results?
What is the cost of the Chlamydophila pneumoniae IgG test at DNA Labs India?
Can a positive IgG test confirm that I currently have a Chlamydophila pneumoniae infection?
What are the common symptoms of Chlamydophila pneumoniae infection?
How is Chlamydophila pneumoniae transmitted?
Is the Chlamydophila pneumoniae IgG test available with home sample collection?
What other tests may be ordered along with the Chlamydophila pneumoniae IgG test?
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