SARS-CoV-2 Antibody IgG CLIA Test
Short Name: COVID-19 IgG CLIA
Also known as: COVID-19 IgG Antibody Test, SARS-CoV-2 IgG Serology Test, Coronavirus Antibody IgG CLIA Test, SARS-CoV-2 IgG Immunoassay
SARS-CoV-2 Antibody IgG CLIA Test test available at DNA Labs India for ₹819. Uses Chemiluminescence Immunoassay (CLIA) on Serum samples. Results in Results are typically available within 1 week after sample collection. You will receive your report via the online portal, email, or WhatsApp.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of the SARS-CoV-2 Antibody IgG CLIA Test is to detect the presence of IgG antibodies against the SARS-CoV-2 virus in a blood sample. This test helps determine if an individual has been previously exposed to COVID-19 and has developed an immune response. It is not used to diagnose an active infection but rather to assess past infection status. The test is also valuable for seroprevalence studies, post-vaccination antibody monitoring, and helping researchers understand the spread and immune dynamics of COVID-19 within populations.
- Test Code
- 40
- CPT Code
- 86769
- ICD Code
- U07.1
- Price
- ₹819
- Sample Type
- Serum
- Result Time
- Results are typically available within 1 week after sample collection. You will receive your report via the online portal, email, or WhatsApp.
- Fasting Required
- No
- Method
- Chemiluminescence Immunoassay (CLIA)
Sample Collection
A duly filled Covid-19 Antibody Test Form (Form 45) is mandatory. No fasting is required. Inform the phlebotomist about any recent COVID-19 vaccination or known immunological conditions.
Method: Venipuncture
Laboratory Analysis
A blood sample of 3 mL (minimum 1 mL) will be collected from a vein in your arm using standard venipuncture technique into a Serum Separator Tube (SST).
Report Delivery
Apply pressure to the puncture site with a cotton ball or bandage to stop bleeding. The sample will be processed and shipped refrigerated or frozen to the laboratory.
Timeline: Results are typically available within 1 week after sample collection. You will receive your report via the online portal, email, or WhatsApp.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the SARS-CoV-2 Antibody IgG CLIA Test is to detect the presence of IgG antibodies against the SARS-CoV-2 virus in a blood sample. This test helps determine if an individual has been previously exposed to COVID-19 and has developed an immune response. It is not used to diagnose an active infection but rather to assess past infection status. The test is also valuable for seroprevalence studies, post-vaccination antibody monitoring, and helping researchers understand the spread and immune dynamics of COVID-19 within populations.
How to Prepare
- Duly filled Covid-19 Antibody Test Form (Form 45) is mandatory before sample collection
- No fasting is required for this test
- Inform the phlebotomist about any recent COVID-19 vaccination
- 3 mL of blood will be collected in a Serum Separator Tube (SST)
- Sample should be shipped refrigerated or frozen to maintain stability
- Avoid strenuous activity at the puncture site for a few hours after collection
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"As an Infectious Disease specialist, I recommend the SARS-CoV-2 IgG CLIA test for patients who suspect they may have had a past COVID-19 infection but were not tested during the acute phase. This test is valuable for understanding individual and population-level exposure to the virus. It is also useful in seroprevalence assessments and post-vaccination antibody monitoring. However, it is important to note that this test cannot diagnose active COVID-19 infection and should not replace RT-PCR or antigen testing for symptomatic individuals. A reactive IgG result suggests past infection or an immune response, but the level and duration of protection cannot be determined by this test alone. Always consult your healthcare provider for proper interpretation of results and clinical guidance."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample collected without a duly filled Covid-19 Antibody Test Form (Form 45)
- Insufficient sample volume (less than 1 mL serum)
- Hemolyzed, lipemic, or grossly contaminated sample
- Sample stored beyond stability limits (Room Temp >8 hrs, Refrigerated >48 hrs, Frozen >1 week)
- Leaking or improperly labeled SST tube
Understanding Your Results
Non-reactive (<1.0 S/CO)
No detectable IgG antibodies to SARS-CoV-2 were found. This may indicate no past infection, testing too early after exposure, or an inadequate immune response. Clinical correlation is recommended.
Reactive (≥1.0 S/CO)
IgG antibodies to SARS-CoV-2 were detected. This suggests a past infection or immune response to the virus or COVID-19 vaccination. A reactive result does not guarantee immunity against future infection. Consult your physician for further guidance.
Consult your doctor if your test result is reactive and you are unsure about your immune status, if you are currently experiencing COVID-19 symptoms (this test is not for active infection diagnosis), if you are immunocompromised and your result is non-reactive despite suspected exposure, or if you need guidance on vaccination and booster doses based on your antibody levels.
Limitations
- ⚠This test cannot diagnose an active or current COVID-19 infection
- ⚠IgG antibody levels may wane over time and may not be detectable months after infection
- ⚠A reactive result does not confirm immunity or protection against future SARS-CoV-2 infection
- ⚠Cannot differentiate between antibodies produced by natural infection versus COVID-19 vaccination
- ⚠Results should always be interpreted in conjunction with clinical history and other diagnostic findings
Risks & Considerations
- ●Minor bruising or soreness at the blood draw site
- ●Slight risk of infection at the puncture site
- ●Rarely, lightheadedness or dizziness during or after blood collection
- ●False-negative results if tested too early after infection
- ●False-positive results due to cross-reactivity with other coronaviruses or recent vaccination
Interfering Factors
- ●Recent COVID-19 vaccination may produce detectable IgG antibodies unrelated to natural infection
- ●Immunocompromised individuals may not produce detectable IgG levels despite past infection
- ●Testing too early after infection (before 1–2 weeks) may yield false-negative results due to insufficient antibody development
- ●Cross-reactivity with antibodies from other common human coronaviruses
- ●Hemolyzed, lipemic, or contaminated serum samples may affect test accuracy
Compare With Similar Tests
| Test | SARS-CoV-2 Antibody IgG CLIA Test | SARS-CoV-2 RT-PCR Test | COVID-19 Rapid Antigen Test | SARS-CoV-2 Antibody IgM CLIA Test | SARS-CoV-2 Total Antibody Test |
|---|---|---|---|---|---|
| Comparison | SARS-CoV-2 Antibody IgG CLIA Test |
Frequently Asked Questions
What is the SARS-CoV-2 Antibody IgG CLIA Test?
What is the cost of the SARS-CoV-2 Antibody IgG CLIA Test at DNA Labs India?
Can this test diagnose an active COVID-19 infection?
Who should get the SARS-CoV-2 Antibody IgG CLIA Test?
What sample is required for this test?
Is Form 45 mandatory for this test?
How long does it take to get the results?
What does a reactive result mean?
What does a non-reactive result mean?
Is home sample collection available for this test?
Does a positive IgG antibody result mean I am immune to COVID-19?
Can recent COVID-19 vaccination affect this test result?
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