CYP2B6 Gene Efavirenz, poor metabolism of NGS Genetic Test
Short Name: CYP2B6 Efavirenz Test
Also known as: CYP2B6 Genotyping, Efavirenz Metabolism Genetic Test, CYP2B6 NGS Test
CYP2B6 Gene Efavirenz, poor metabolism of NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect genetic variants in the CYP2B6 gene that affect the metabolism of Efavirenz, allowing for personalized HIV therapy to minimize side effects and optimize treatment efficacy.
- Test Code
- 4674
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Ensure proper identification and clinical history is provided.
Method: Blood Draw or Saliva Collection
Laboratory Analysis
Sample collected via blood draw or saliva kit following standard procedures.
Report Delivery
Apply pressure to the puncture site if blood is drawn. Store sample as instructed.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect genetic variants in the CYP2B6 gene that affect the metabolism of Efavirenz, allowing for personalized HIV therapy to minimize side effects and optimize treatment efficacy.
How to Prepare
- Use sterile equipment for blood collection
- For saliva, follow the kit instructions carefully
- Label the sample with patient details and date
- Transport sample at ambient room temperature
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This genetic test is crucial for personalizing HIV treatment by identifying patients at risk of side effects from Efavirenz, enabling dose adjustments or alternative therapies."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Contaminated or hemolyzed sample
- Incorrect labeling or missing information
Understanding Your Results
No pathogenic variants detected
Normal metabolism of Efavirenz; standard dosing may be appropriate
Pathogenic variants detected
Poor metabolism of Efavirenz; increased risk of side effects, consider dose adjustment or alternative therapy
If you experience symptoms like dizziness, confusion, depression, or hallucinations while taking Efavirenz, consult your healthcare provider immediately to discuss test results and treatment options.
Limitations
- ⚠Test only detects known variants in the CYP2B6 gene
- ⚠Does not account for other factors affecting drug metabolism such as liver function
- ⚠Results should be interpreted in conjunction with clinical history and other tests
Risks & Considerations
- ●Minor pain or bruising at blood draw site
- ●Very low risk of infection
- ●No significant risks from saliva collection
Interfering Factors
- ●Sample contamination
- ●Degraded DNA quality
- ●Incorrect sample collection or handling
Frequently Asked Questions
What is the CYP2B6 Gene Efavirenz test?
Why is this test important?
How is the test performed?
What are the symptoms of poor Efavirenz metabolism?
How long does it take to get results?
What is the cost of the test?
Is home sample collection available?
What should I do if I have poor metabolism?
Are there any risks to the test?
How accurate is the test?
Can this test be used for other drugs?
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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