Skip to main content
DNA Labs India

DNMT3A Gene Acute myeloid leukemia, somatic, DNMT3A related NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

DNMT3A Gene Acute myeloid leukemia, somatic, DNMT3A related NGS Genetic Test

Short Name: DNMT3A Gene AML NGS Test

Also known as: DNMT3A Mutation Test, AML Genetic Test, Somatic DNMT3A Analysis

DNMT3A Gene Acute myeloid leukemia, somatic, DNMT3A related NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks from sample receipt. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify DNMT3A gene mutations in AML patients for diagnosis, prognosis assessment, and personalized treatment planning.

Test Code
2830
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks from sample receipt
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Clinical history review and genetic counseling recommended prior to testing.

Method: Blood Draw

Step 2

Laboratory Analysis

Blood sample collected by a trained phlebotomist using sterile techniques.

Step 3

Report Delivery

Sample labeled and transported to the laboratory for analysis.

Timeline: 3 to 4 weeks from sample receipt

Patient Instructions

1
Before the Test:Consult with an oncologist and genetic counselor to discuss test implications and family history.
2
During the Test:Blood sample collection is a standard procedure with minimal discomfort.
3
After the Test:Wait for the report and schedule a follow-up with your doctor for interpretation and next steps.

About This Test

Who Should Get This Test

To identify DNMT3A gene mutations in AML patients for diagnosis, prognosis assessment, and personalized treatment planning.

How to Prepare

  • Fasting not required
  • Use sterile collection equipment
  • Ensure proper sample labeling
  • Avoid hemolysis during blood draw

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for DNMT3A mutations can guide personalized treatment in AML, improving patient outcomes and informing family risk assessment."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodBlood Draw

Sample Stability

Blood: Stable for 24 hours at room temperature
Extracted DNA: Stable for extended periods if stored properly
Sample Rejection Criteria:
  • Hemolyzed or clotted sample
  • Insufficient sample volume
  • Improper labeling or documentation

Understanding Your Results

Results indicate the presence or absence of DNMT3A gene mutations, which are associated with AML.
📊

Mutation Detected

Presence of DNMT3A mutation linked to AML; consider targeted therapy and genetic counseling.

📊

No Mutation Detected

DNMT3A mutation not found; other genetic or non-genetic factors may be involved.

⚠️ When to Consult a Doctor:

If symptoms of AML persist, if genetic counseling is needed, or if results indicate mutation for treatment planning.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Results require clinical correlation
  • ⚠Not a standalone diagnostic tool

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●Genetic information may have psychological or familial implications

Interfering Factors

  • ●Poor sample quality
  • ●Contamination during collection
  • ●Technical errors in sequencing

Compare With Similar Tests

TestDNMT3A Gene Acute myeloid leukemia, somatic, DNMT3A related NGS Genetic TestFLT3 Mutation TestNPM1 Mutation Test
ComparisonDNMT3A Gene Acute myeloid leukemia, somatic, DNMT3A related NGS Genetic TestBoth are NGS tests for AML, but target different genes; FLT3 is another common mutation in AML.Focuses on NPM1 gene mutations, often used alongside DNMT3A testing for comprehensive AML profiling.

Frequently Asked Questions

What is the DNMT3A gene and its role in AML?
The DNMT3A gene encodes an enzyme involved in DNA methylation; mutations are common in AML and affect gene regulation, contributing to cancer development.
Who should consider taking this genetic test?
Individuals with suspected AML, family history of AML or related cancers, or those requiring personalized treatment planning.
What are the symptoms of DNMT3A-related AML?
Symptoms include fever, fatigue, easy bruising, shortness of breath, pale skin, and swollen lymph nodes, similar to other AML types.
How is the test performed?
The test uses next-generation sequencing (NGS) on a blood or DNA sample to detect DNMT3A gene mutations.
Is fasting required before the test?
No, fasting is not required for this genetic test.
How long does it take to get the results?
Results are typically available within 3 to 4 weeks after sample collection.
What is the cost of the DNMT3A gene test?
The test costs INR 20,000 at DNA Labs India, with free home sample collection available.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection across many cities in India for this test.
What does a positive result mean?
A positive result indicates the presence of a DNMT3A mutation, which may guide treatment decisions and require genetic counseling.
Can this test predict the risk of developing AML?
The test identifies somatic mutations in AML patients; it is not typically used for risk prediction in asymptomatic individuals without family history.
Is the test covered by insurance?
Coverage varies by insurance plan; it is recommended to check with your provider for specific details.
How accurate is the NGS genetic test?
NGS technology is highly accurate for detecting known mutations, but results should be interpreted in the context of clinical findings.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

DPD Gene Mutations (5-FU Toxicity) Detection Test

₹9,828

T-Cell Gene Rearrangement Mutation Detection Test

₹20,000

BCR-ABL Gene Rearrangement PCR Qualitative Test

₹5,000

5-Fluorouracil (5FU) Toxicity Test

₹10,000

CALR Mutation Detection Test

₹6,000

Cancer Targeted Gene Panel: Lung Test

₹27,000
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.