EGFR Gene EGFR, selective sequencing of exons 18-21 NGS Genetic Test
Short Name: EGFR Exons 18-21 NGS Test
Also known as: EGFR Mutation Test, EGFR Sequencing Test, Epidermal Growth Factor Receptor Gene Test
EGFR Gene EGFR, selective sequencing of exons 18-21 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify mutations in exons 18-21 of the EGFR gene, which are critical for diagnosing certain cancers, particularly non-small cell lung cancer, and for guiding targeted therapy decisions to improve treatment efficacy and patient prognosis.
- Test Code
- 2871
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
Genetic counseling is recommended to discuss the test implications, and a clinical history of the patient should be provided. No fasting is required, but ensure proper identification and prescription.
Method: Venipuncture
Laboratory Analysis
A blood sample is collected via venipuncture from a vein in the arm, or a drop of blood on an FTA card may be used. The procedure is quick and minimally invasive.
Report Delivery
The sample is labeled and transported to the laboratory under appropriate conditions for DNA extraction and NGS analysis.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify mutations in exons 18-21 of the EGFR gene, which are critical for diagnosing certain cancers, particularly non-small cell lung cancer, and for guiding targeted therapy decisions to improve treatment efficacy and patient prognosis.
How to Prepare
- Bring a valid ID and doctor's prescription
- Ensure the sample is collected in a sterile environment
- For blood samples, use the provided EDTA tube or FTA card
- Avoid hemolysis during blood draw
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"EGFR testing is crucial for identifying targeted therapy options in lung cancer patients, improving treatment outcomes and personalizing care."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Improper labeling or documentation
Understanding Your Results
Mutation Detected
Presence of EGFR mutation in one or more exons, which may indicate eligibility for targeted cancer therapies. Consult an oncologist for treatment options.
No Mutation Detected
No mutations found in exons 18-21. This does not rule out mutations in other EGFR exons or other genetic factors. Clinical correlation is advised.
Variant of Uncertain Significance
A genetic variant was identified but its clinical significance is unknown. Further testing or genetic counseling may be recommended.
Consult a doctor if you experience symptoms of lung cancer, have a family history of EGFR mutations, or if test results indicate mutations for personalized treatment planning.
Limitations
- ⚠This test only covers exons 18-21 of the EGFR gene; mutations in other exons may not be detected
- ⚠May not identify all types of EGFR mutations, such as large rearrangements
- ⚠Results should be interpreted in conjunction with clinical findings and other diagnostic tests
Risks & Considerations
- ●Minor bruising or pain at the blood draw site
- ●Rare risk of infection
- ●No significant risks associated with the genetic analysis itself
Interfering Factors
- ●Sample contamination during collection or processing
- ●DNA degradation due to improper storage
- ●Presence of inhibitors in the sample affecting NGS analysis
Compare With Similar Tests
| Test | EGFR Gene EGFR, selective sequencing of exons 18-21 NGS Genetic Test | EGFR Full Gene Sequencing | KRAS Mutation Test | ALK Rearrangement Test | ROS1 Fusion Test |
|---|---|---|---|---|---|
| Comparison | EGFR Gene EGFR, selective sequencing of exons 18-21 NGS Genetic Test |
Frequently Asked Questions
What is the EGFR gene?
Why is selective sequencing of exons 18-21 performed?
Who should consider this test?
How is the test performed?
What is the cost of the EGFR gene test?
Is home sample collection available?
How long does it take to get results?
What do the test results mean?
Are there any risks associated with the test?
Can this test detect all EGFR mutations?
What is the difference between this test and full EGFR gene sequencing?
How accurate is the EGFR gene test?
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