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FERMT3 Gene Leukocyte adhesion deficiency type 3 NGS Genetic Test

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FERMT3 Gene Leukocyte adhesion deficiency type 3 NGS Genetic Test

Also known as: LAD3, LAD-III, Leukocyte Adhesion Deficiency Type 3

FERMT3 Gene Leukocyte adhesion deficiency type 3 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS (Next-Generation Sequencing) on Blood, Extracted DNA, or FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of this test is to identify mutations in the FERMT3 gene that cause Leukocyte Adhesion Deficiency Type 3, enabling early diagnosis and management to prevent complications.

Test Code
5596
Price
₹20,000
Sample Type
Blood, Extracted DNA, or FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS (Next-Generation Sequencing)
Step 1

Sample Collection

Clinical history and genetic counseling recommended.

Method: Venipuncture or finger prick

Step 2

Laboratory Analysis

Standard blood draw or finger prick procedure.

Step 3

Report Delivery

Sample sent to lab for NGS analysis.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling and clinical evaluation recommended.
2
During the Test:Blood sample collection for DNA extraction and sequencing.
3
After the Test:Report generation and genetic counseling for result interpretation.

About This Test

Who Should Get This Test

The purpose of this test is to identify mutations in the FERMT3 gene that cause Leukocyte Adhesion Deficiency Type 3, enabling early diagnosis and management to prevent complications.

How to Prepare

  • Ensure proper sample labeling
  • Follow aseptic techniques
  • Store sample at appropriate temperature

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for FERMT3 mutations is crucial for diagnosing LAD3 and initiating timely treatment to manage infections and bleeding disorders."

Last medically reviewed: September 3, 2026

Test Parameters & Specifications

Sample TypeBlood, Extracted DNA, or FTA Card
Sample VolumeVaries
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or finger prick

Sample Stability

Blood: 24 hours at room temperature
Extracted DNA: stable for longer periods
Sample Rejection Criteria:
  • Hemolyzed sample
  • Insufficient volume
  • Incorrect container

Understanding Your Results

Results indicate the presence or absence of mutations in the FERMT3 gene associated with LAD3.
📊

Confirms diagnosis of LAD3. Consult geneticist for management.

📊

LAD3 unlikely, but clinical correlation needed.

📊

Further testing or family studies recommended.

⚠️ When to Consult a Doctor:

If symptoms of recurrent infections, bleeding disorders, or family history of LAD3 are present.

Limitations

  • May not detect all mutations
  • Requires genetic counseling for interpretation
  • Results may include variants of uncertain significance

Risks & Considerations

  • Minimal risk from blood draw
  • Psychological impact of genetic results

Interfering Factors

  • Degraded DNA
  • Contaminated sample
  • Incorrect sample type

Compare With Similar Tests

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Frequently Asked Questions

What is FERMT3 Gene Leukocyte Adhesion Deficiency Type 3?
LAD3 is a rare genetic disorder caused by mutations in the FERMT3 gene, leading to impaired immune cell function and increased infection risk.
What are the symptoms of LAD3?
Symptoms include recurrent bacterial infections, delayed wound healing, bleeding disorders, failure to thrive, and delayed growth.
How is LAD3 diagnosed?
Diagnosis involves genetic testing, such as the FERMT3 Gene NGS Test, to identify mutations in the FERMT3 gene.
What does the NGS Genetic Test involve?
The test uses Next-Generation Sequencing to analyze the FERMT3 gene for mutations from a blood or DNA sample.
What is the cost of the test?
The test costs INR 20,000 at DNA Labs India.
Is home sample collection available?
Yes, free home sample collection is available for online bookings across India.
How long does it take to get results?
Results are typically available in 3 to 4 weeks.
What should I do if the test is positive?
Consult a geneticist or immunologist for management, which may include antibiotics and supportive care.
Is the test covered by insurance?
Coverage depends on your insurance plan; check with your provider for details.
Can LAD3 be treated?
Treatment focuses on managing infections and may include hematopoietic stem cell transplantation in severe cases.
Is genetic counseling necessary?
Yes, genetic counseling is recommended before and after testing to understand results and implications.
What are the risks of the test?
Risks are minimal, primarily related to blood draw, but psychological impact of results should be considered.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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