GDF1 Gene Transposition of great arteries, dextro-looped 3 NGS Genetic Test
Short Name: GDF1 TGA NGS
Also known as: GDF1 Gene Mutation Test, TGA Dextro-Looped 3 Genetic Test, GDF1 Sequencing
GDF1 Gene Transposition of great arteries, dextro-looped 3 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports are typically available within 3 to 4 weeks after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify mutations in the GDF1 gene that are associated with dextro-looped 3 transposition of great arteries. It aids in confirming a clinical diagnosis, assessing recurrence risk in families, and guiding reproductive decisions.
- Test Code
- 5962
- CPT Code
- 81408
- ICD Code
- Q20.3
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Reports are typically available within 3 to 4 weeks after sample receipt.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No special preparation required. However, a genetic counseling session is recommended before the test to discuss the implications.
Method: Venipuncture or Fingerstick
Laboratory Analysis
Blood sample is drawn by a trained phlebotomist. For FTA card, a simple fingerstick is sufficient.
Report Delivery
No restrictions. Resume normal activities immediately.
Timeline: Reports are typically available within 3 to 4 weeks after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify mutations in the GDF1 gene that are associated with dextro-looped 3 transposition of great arteries. It aids in confirming a clinical diagnosis, assessing recurrence risk in families, and guiding reproductive decisions.
How to Prepare
- Ensure the sample is labeled correctly with patient details.
- For FTA card, allow the blood spot to air dry completely before sealing.
- Transport the sample at ambient temperature to the laboratory.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Early genetic diagnosis of GDF1 mutations can guide management and family counseling for TGA."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Improperly labeled sample
- Sample received after prolonged transit without proper storage
Understanding Your Results
Positive (Pathogenic variant detected)
The patient has a mutation in GDF1 associated with TGA. Genetic counseling is recommended for the family.
Negative (No pathogenic variant detected)
No mutation in GDF1 was found. Other genetic or non-genetic causes should be considered.
Variant of Uncertain Significance (VUS)
A genetic variant was found but its clinical significance is unknown. Further testing of family members may help clarify.
If your child has symptoms like cyanosis, rapid breathing, or poor feeding, seek immediate medical attention. If you have a family history of TGA, consult a geneticist for risk assessment.
Limitations
- ⚠This test only analyzes the GDF1 gene; other genetic causes of TGA may not be detected.
- ⚠Variant of uncertain significance (VUS) may be reported; further family studies may be needed.
- ⚠NGS may not detect large deletions/duplications or deep intronic variants.
- ⚠Test does not assess non-genetic causes of TGA.
Risks & Considerations
- ●Minimal risk of bruising or infection at blood draw site
- ●Psychological impact of genetic results
- ●Potential for incidental findings
Interfering Factors
- ●Contaminated or degraded DNA sample
- ●Recent blood transfusion (within 2 weeks)
- ●Bone marrow transplantation
- ●Maternal cell contamination in prenatal samples
Compare With Similar Tests
| Test | GDF1 Gene Transposition of great arteries, dextro-looped 3 NGS Genetic Test | Chromosomal Microarray (CMA) | Whole Exome Sequencing (WES) | Targeted Gene Panel (Cardiac) |
|---|---|---|---|---|
| Comparison | GDF1 Gene Transposition of great arteries, dextro-looped 3 NGS Genetic Test |
Frequently Asked Questions
What is the cost of the GDF1 gene NGS genetic test in India?
What is dextro-looped 3 transposition of great arteries?
How is the GDF1 gene related to TGA?
What sample is needed for this test?
Is fasting required before the test?
How long does it take to get the results?
Can this test be done on a newborn?
Does the test require genetic counseling?
What does a positive result mean?
Are there any risks associated with the test?
Is home sample collection available?
Can this test detect other genetic causes of TGA?
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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