HBOC Extended Panel [Hereditary Breast And Ovarian Cancer] (32 Genes) Test
Short Name: HBOC Extended Panel
Also known as: HBOC Panel, Hereditary Cancer Panel, 32-Gene Breast and Ovarian Cancer Test
HBOC Extended Panel [Hereditary Breast And Ovarian Cancer] (32 Genes) Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Peripheral Blood samples. Results in 4-5 weeks from sample collection. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the HBOC Extended Panel test is to identify inherited mutations in 32 genes linked to hereditary breast and ovarian cancer, allowing for early risk assessment, personalized screening, and preventive interventions to reduce cancer incidence and mortality.
- Test Code
- 3019
- Price
- ₹20,000
- Sample Type
- Peripheral Blood
- Result Time
- 4-5 weeks from sample collection
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation is required, but inform your doctor about any medications or recent medical procedures. A doctor's prescription may be needed unless for surgery, pregnancy, or travel abroad cases.
Method: Venipuncture
Laboratory Analysis
A healthcare professional will collect a blood sample via venipuncture from a vein in your arm, using an EDTA vacutainer. The process is quick and minimally invasive.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Resume normal activities immediately. Store the sample in a cool pack if not analyzed immediately.
Timeline: 4-5 weeks from sample collection
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the HBOC Extended Panel test is to identify inherited mutations in 32 genes linked to hereditary breast and ovarian cancer, allowing for early risk assessment, personalized screening, and preventive interventions to reduce cancer incidence and mortality.
How to Prepare
- Ensure the patient is relaxed and hydrated
- Use aseptic technique to avoid contamination
- Label the sample correctly with patient details
- Transport the sample to the lab within 24 hours in a cool pack
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is crucial for individuals with a family history of breast or ovarian cancer to assess genetic risk and plan preventive measures, such as enhanced screening or prophylactic surgeries."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample hemolyzed or clotted
- Insufficient volume (<2 ml)
- Incorrect container or labeling
- Sample older than stability period
Understanding Your Results
Positive for Pathogenic Variant
High risk for hereditary breast and ovarian cancer; recommend enhanced screening, genetic counseling, and discussion of preventive options.
Negative for Pathogenic Variants
No known mutations detected in the tested genes; however, family history and other risk factors should still be considered for ongoing monitoring.
Variant of Uncertain Significance (VUS)
A genetic variant was found, but its clinical significance is unknown; recommend periodic re-evaluation and genetic counseling.
Inconclusive
Test could not determine a clear result due to technical issues; may require repeat testing or additional analysis.
Consult a doctor or genetic counselor immediately after receiving results to understand implications, plan screening or prevention strategies, and discuss family testing options.
Limitations
- ⚠Does not detect all possible genetic mutations or variants of uncertain significance (VUS)
- ⚠Cannot predict the exact age of cancer onset or severity
- ⚠Results may have psychological impact and require genetic counseling
- ⚠Limited to known genes in the panel; other risk factors not assessed
Risks & Considerations
- ●Psychological distress from positive results
- ●Potential for false positives or negatives
- ●Insurance or discrimination concerns (though legal protections exist)
- ●Family implications requiring disclosure
Interfering Factors
- ●Poor sample quality due to hemolysis or contamination
- ●Recent blood transfusions affecting DNA integrity
- ●Use of certain medications that may alter genetic expression
- ●Improper sample storage or handling
Compare With Similar Tests
| Test | HBOC Extended Panel [Hereditary Breast And Ovarian Cancer] (32 Genes) | BRCA1/BRCA2 Single Gene Test | Hereditary Cancer Panel (Other) | Direct-to-Consumer Genetic Test | Somatic Tumor Testing |
|---|---|---|---|---|---|
| Comparison | HBOC Extended Panel [Hereditary Breast And Ovarian Cancer] (32 Genes) |
Frequently Asked Questions
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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