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DNA Labs India

Hereditary Cancer Panel Test

DNA Labs India | ISO 9001:2015 Certified

Hereditary Cancer Panel Test

Short Name: HCP

Also known as: Cancer Risk Panel, Hereditary Cancer Genetic Test, Multi-Gene Cancer Panel

Hereditary Cancer Panel Test test available at DNA Labs India for ₹18,000. Uses Next-Generation Sequencing (NGS) on Blood samples. Results in Results are typically available within 10-14 business days after the sample reaches the laboratory.. Free home collection in 300+ cities across India.

Molecular / GeneticAdult🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of the Hereditary Cancer Panel is to identify inherited genetic mutations that increase an individual's susceptibility to developing certain types of cancer. This information is crucial for individuals with a strong family history of cancer, those diagnosed with cancer at a young age, or those with multiple cancers in the family. The test helps in risk stratification, guiding clinical management such as enhanced surveillance, prophylactic surgeries, or chemoprevention. It also provides valuable information for family members who may be at risk, enabling cascade testing and early intervention.

Test Code
6453
CPT Code
81432
ICD Code
Z15.09
Price
₹18,000
Sample Type
Blood
Result Time
Results are typically available within 10-14 business days after the sample reaches the laboratory.
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No special preparation is required. However, it is recommended to bring any previous genetic test results or family history documentation.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in your arm. The procedure is quick and minimally invasive.

Step 3

Report Delivery

You may resume normal activities immediately. A small bruise or soreness at the puncture site is normal and resolves quickly.

Timeline: Results are typically available within 10-14 business days after the sample reaches the laboratory.

Patient Instructions

1
Before the Test:Before the test, you will have a pre-test counseling session with a genetic counselor to discuss the purpose, benefits, risks, and limitations of the test. This helps you make an informed decision.
2
During the Test:The test involves a simple blood draw. The sample is sent to the laboratory for NGS analysis. You may go home immediately after the collection.
3
After the Test:After the test, you will receive your results in 10-14 days. A post-test counseling session is provided to explain the results and discuss next steps.

About This Test

Who Should Get This Test

The purpose of the Hereditary Cancer Panel is to identify inherited genetic mutations that increase an individual's susceptibility to developing certain types of cancer. This information is crucial for individuals with a strong family history of cancer, those diagnosed with cancer at a young age, or those with multiple cancers in the family. The test helps in risk stratification, guiding clinical management such as enhanced surveillance, prophylactic surgeries, or chemoprevention. It also provides valuable information for family members who may be at risk, enabling cascade testing and early intervention.

How to Prepare

  • No fasting required
  • Inform the lab if you have had a blood transfusion or bone marrow transplant
  • Wear comfortable clothing with easy access to the arm

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"Early identification of hereditary cancer syndromes allows for tailored surveillance and risk-reduction strategies, potentially reducing cancer mortality in high-risk families."

Last medically reviewed: September 15, 2026

Test Parameters & Specifications

Sample TypeBlood
Sample Volume5 mL
ContainerEDTA lavender-top tube
Collection MethodVenipuncture

Sample Stability

Blood sample stable for 24 hours at room temperature
Stable for 7 days when refrigerated at 2-8°C
Do not freeze whole blood
Sample Rejection Criteria:
  • Clotted sample
  • Hemolyzed sample
  • Incorrect labeling
  • Sample received after 7 days without proper storage

Understanding Your Results

The results of the Hereditary Cancer Panel are interpreted by a clinical geneticist. Variants are classified according to ACMG guidelines as Pathogenic, Likely Pathogenic, Variant of Uncertain Significance (VUS), Likely Benign, or Benign. Only pathogenic and likely pathogenic variants are considered clinically actionable.
📊

Pathogenic variant detected

Increased risk for associated cancer(s). Clinical management and family testing recommended.

📊

Likely pathogenic variant detected

High likelihood of increased risk. Similar management as pathogenic variant.

📊

Variant of Uncertain Significance (VUS)

Insufficient evidence to determine risk. Additional testing or family studies may be needed.

📊

No pathogenic variant detected

No known hereditary cancer mutation found. Risk may still exist based on family history.

⚠️ When to Consult a Doctor:

Consult your physician or genetic counselor if you receive a positive result (pathogenic or likely pathogenic variant) to discuss surveillance and prevention options. Also, consult if you have a VUS to understand its implications.

Limitations

  • This test does not detect all possible genetic causes of cancer
  • Variants of uncertain significance (VUS) may be reported, which require further investigation
  • Negative results do not eliminate the risk of cancer entirely
  • Results should be interpreted in the context of personal and family history

Risks & Considerations

  • Psychological impact of learning about increased cancer risk
  • Potential for variants of uncertain significance (VUS) causing anxiety
  • Risk of genetic discrimination (though limited by laws in some countries)

Interfering Factors

  • Recent blood transfusion (within 7 days) may dilute DNA
  • Bone marrow transplantation can affect results
  • Clotted or hemolyzed samples may cause test failure
  • Certain medications or supplements are not known to interfere with genetic testing

Compare With Similar Tests

TestHereditary Cancer PanelHereditary Cancer PanelBRCA1/BRCA2 Only
ComparisonHereditary Cancer Panel

Frequently Asked Questions

What is the Hereditary Cancer Panel test?
It is a genetic test that screens for mutations in 50+ genes associated with hereditary cancer syndromes, helping assess your risk for various cancers.
Who should take this test?
Individuals with a family history of cancer, early-onset cancer, multiple cancers in the family, or those seeking proactive health management.
How is the test performed?
A blood sample is collected from your arm and sent to the lab for next-generation sequencing (NGS) analysis.
Do I need to fast before the test?
No, fasting is not required for this test.
How long does it take to get results?
Results are typically available within 10-14 days after the sample reaches the laboratory.
What does a positive result mean?
A positive result indicates a pathogenic variant that increases your risk for certain cancers. You will receive genetic counseling to discuss next steps.
What is a Variant of Uncertain Significance (VUS)?
A VUS is a genetic change whose impact on cancer risk is not yet known. Further testing or family studies may be needed.
Is genetic counseling included?
Yes, free pre- and post-test genetic counseling is included with the test.
Can this test detect all types of cancer?
No, it covers genes associated with common hereditary cancers, but not all cancers have a known hereditary component.
Will my insurance cover the cost?
Insurance coverage varies. Please check with your provider. The test is not covered under most government schemes.
Is home sample collection available?
Yes, free home sample collection is available across India.
How accurate is the test?
The test uses NGS technology with >99.9% accuracy for detecting variants in the analyzed genes.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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