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HLA - AB (Class 1) Typing Test

DNA Labs India | ISO 9001:2015 Certified

HLA - AB (Class 1) Typing Test

Short Name: HLA-AB Class 1 Typing

Also known as: HLA-A and HLA-B Typing, Class I HLA Typing, MHC Class I Typing

HLA - AB (Class 1) Typing Test test available at DNA Labs India for ₹8,658. Uses Reverse SSOP - Luminex on Whole Blood samples. Results in Results are typically available within 10-12 days after sample receipt at the laboratory.. Free home collection in 300+ cities across India.

HLA Typing🏠 Home Collection

🩺 Medically Reviewed By

Overview

The primary purpose of the HLA-AB Class 1 Typing Test is to assess genetic compatibility for organ and bone marrow transplantation, minimizing rejection risks. It also supports the diagnosis and management of autoimmune disorders by identifying HLA associations.

Test Code
777
Price
₹8,658
Sample Type
Whole Blood
Result Time
Results are typically available within 10-12 days after sample receipt at the laboratory.
Fasting Required
No
Method
Reverse SSOP - Luminex
Step 1

Sample Collection

Doctor's prescription on letterhead with 1 photograph each of recipient and donor duly stamped AND Consent form for HLA Typing for Solid organ transplant (Form 33) is mandatory. No specific dietary restrictions, but consult your physician.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample is collected via venipuncture from a vein in the arm. The process is quick and typically takes a few minutes.

Step 3

Report Delivery

Ship sample refrigerated; do not freeze. Maintain cold chain during transport to laboratory.

Timeline: Results are typically available within 10-12 days after sample receipt at the laboratory.

Patient Instructions

1
Before the Test:Ensure you have the required doctor's prescription and consent form. No fasting needed, but follow any specific instructions from your physician.
2
During the Test:A blood sample will be drawn from your arm. The procedure is straightforward and minimally invasive.
3
After the Test:Apply pressure to the puncture site to avoid bruising. Resume normal activities unless otherwise advised.

About This Test

Who Should Get This Test

The primary purpose of the HLA-AB Class 1 Typing Test is to assess genetic compatibility for organ and bone marrow transplantation, minimizing rejection risks. It also supports the diagnosis and management of autoimmune disorders by identifying HLA associations.

How to Prepare

  • Use Lavender Top (EDTA) or Yellow Top (ACD) tube as specified
  • Label tube correctly with patient details
  • Ensure sample is refrigerated after collection
  • Transport to lab within 96 hours under refrigeration

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"HLA typing is critical for assessing compatibility in organ transplantation and diagnosing autoimmune conditions, ensuring optimal patient outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole Blood
Sample Volume4 mL (min. 3 mL) in Lavender Top (EDTA) tube OR 6 mL (min. 3 mL) in Yellow Top (ACD) tube
ContainerLavender Top (EDTA) tube or Yellow Top (ACD) tube
Collection MethodVenipuncture

Sample Stability

Room Temperature
Refrigerator (2-8°C)
Frozen
Sample Rejection Criteria:
  • Sample hemolyzed or clotted
  • Insufficient volume (<3 mL)
  • Incorrect tube type
  • Missing consent form or prescription
  • Sample not refrigerated or frozen incorrectly

Understanding Your Results

Results from HLA-AB Class 1 Typing identify specific alleles, which are interpreted in the context of transplant compatibility or disease association. A match between donor and recipient reduces rejection risk.
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Matched HLA alleles

High compatibility for transplantation; lower risk of rejection.

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Mismatched HLA alleles

Potential for rejection; may require additional immunosuppression or donor reconsideration.

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Specific HLA types associated with autoimmune diseases

May indicate genetic predisposition; clinical correlation needed for diagnosis.

⚠️ When to Consult a Doctor:

Consult your physician or transplant specialist to discuss results, especially if planning transplantation or managing autoimmune conditions. Immediate consultation if results show incompatibility or unexpected findings.

Limitations

  • Results are for compatibility assessment, not definitive diagnosis of diseases
  • May not detect all HLA variants; additional testing might be needed
  • Turnaround time of 10-12 days may delay urgent decisions

Risks & Considerations

  • Minor bruising or pain at puncture site
  • Rare risk of infection
  • Faintness or dizziness during blood draw

Interfering Factors

  • Improper sample storage (e.g., freezing when not allowed)
  • Hemolyzed or clotted blood sample
  • Insufficient sample volume
  • Contamination during collection
  • Recent blood transfusion may affect results

Compare With Similar Tests

TestHLA - AB (Class 1) Typing Test
ComparisonHLA - AB (Class 1) Typing Test

Frequently Asked Questions

What is the HLA-AB Class 1 Typing Test?
It is a laboratory test that identifies specific genetic markers (HLA-A and HLA-B antigens) on white blood cells, crucial for transplant compatibility and autoimmune disease diagnosis.
Why is this test important for transplantation?
HLA compatibility between donor and recipient reduces the risk of organ rejection, ensuring better transplant outcomes.
How is the test performed?
A blood sample is collected and analyzed using techniques like PCR or reverse SSOP-Luminex to identify HLA alleles.
What sample is required?
4-6 mL of whole blood in an EDTA or ACD tube, shipped refrigerated.
How long does it take to get results?
Results are typically available within 10-12 days after the sample reaches the laboratory.
Is the test painful?
The blood draw may cause minor discomfort, but it is generally well-tolerated.
What are the risks associated with the test?
Risks include minor bruising, pain, or faintness at the puncture site; serious complications are rare.
How should I prepare for the test?
Ensure you have a doctor's prescription and consent form. No fasting is required.
What do the results mean?
Results show specific HLA alleles; matched alleles indicate compatibility for transplants, while mismatches may require further evaluation.
Can this test diagnose autoimmune diseases?
It can identify HLA associations with autoimmune conditions like rheumatoid arthritis, but diagnosis requires clinical correlation.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection across India for this test.
What is the cost of the test?
The cost is INR 8658, which includes home collection and report delivery.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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