HLA-B*57:01 Genotyping (for Abacavir Hypersensitivity) Test
Short Name: HLA-B*57:01 Genotyping
Also known as: HLA-B*57:01 Test, Abacavir Hypersensitivity Genotyping
HLA-B*57:01 Genotyping (for Abacavir Hypersensitivity) Test test available at DNA Labs India for ₹4,000. Uses Sanger Sequencing on Peripheral blood samples. Results in Reports are typically available within 1 week after sample collection.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of HLA-B*57:01 genotyping is to identify individuals at risk of developing abacavir hypersensitivity, enabling healthcare providers to prescribe alternative antiretroviral drugs for HIV management and prevent potentially life-threatening allergic reactions.
- Test Code
- 3046
- Price
- ₹4,000
- Sample Type
- Peripheral blood
- Result Time
- Reports are typically available within 1 week after sample collection.
- Fasting Required
- No
- Method
- Sanger Sequencing
Sample Collection
No special preparation is required. Inform your doctor about any medications or medical conditions.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm using a sterile needle.
Report Delivery
Apply pressure to the puncture site with a cotton ball to stop bleeding. You may resume normal activities.
Timeline: Reports are typically available within 1 week after sample collection.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of HLA-B*57:01 genotyping is to identify individuals at risk of developing abacavir hypersensitivity, enabling healthcare providers to prescribe alternative antiretroviral drugs for HIV management and prevent potentially life-threatening allergic reactions.
How to Prepare
- Ensure proper patient identification
- Use sterile equipment for sample collection
- Label the sample correctly with patient details
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is crucial for patients starting abacavir to prevent severe hypersensitivity reactions and guide alternative HIV therapy."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or lipemic samples
- Insufficient sample volume
- Improperly labeled or contaminated samples
Understanding Your Results
Positive (HLA-B*57:01 Detected)
High risk of abacavir hypersensitivity. Abacavir should be avoided, and alternative HIV medications should be considered.
Negative (HLA-B*57:01 Not Detected)
Low risk of abacavir hypersensitivity. Abacavir can be prescribed with caution, monitoring for any symptoms.
Consult your doctor if you experience symptoms like fever, rash, or difficulty breathing after taking abacavir, or before starting any HIV treatment.
Limitations
- ⚠Does not detect all genetic variants related to drug hypersensitivity
- ⚠Clinical correlation with symptoms is necessary
- ⚠Results should be interpreted by a qualified healthcare provider
Risks & Considerations
- ●Minor bruising or pain at the puncture site
- ●Rare risk of infection or fainting
Interfering Factors
- ●Sample contamination
- ●Improper sample handling or storage
- ●Recent blood transfusions may affect results
Compare With Similar Tests
| Test | HLA-B*57:01 Genotyping (for Abacavir Hypersensitivity) | HLA-B*57:01 PCR | HIV Viral Load Test |
|---|---|---|---|
| Comparison | HLA-B*57:01 Genotyping (for Abacavir Hypersensitivity) | Similar detection method but may use different technology; Sanger sequencing is considered gold standard. | Measures HIV levels in blood, not genetic risk for drug hypersensitivity. |
Frequently Asked Questions
What is HLA-B*57:01 genotyping?
Why is this test important for HIV patients?
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What does a positive result mean?
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