HLA DNA High Resolution Typing - DQB1 Locus Test
Short Name: HLA DQB1 Typing
Also known as: HLA-DQB1 High Resolution Typing
HLA DNA High Resolution Typing - DQB1 Locus Test test available at DNA Labs India for ₹8,000. Uses PCR, Sequencing on Whole blood in EDTA or ACD tube, or Buccal swab samples. Results in 10-12 days from sample collection. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
This test is performed to determine the HLA-DQB1 type for assessing compatibility in organ and bone marrow transplants, aiding in the diagnosis of autoimmune diseases, and supporting genetic research and susceptibility studies. It helps clinicians make informed decisions regarding transplant matching and disease management.
- Test Code
- 804
- Price
- ₹8,000
- Sample Type
- Whole blood in EDTA or ACD tube, or Buccal swab
- Result Time
- 10-12 days from sample collection
- Fasting Required
- No
- Method
- PCR, Sequencing
Sample Collection
No special preparation required. Inform the healthcare provider about any medications or recent medical procedures.
Method: Blood draw or Buccal swab
Laboratory Analysis
A blood sample will be drawn from a vein in your arm using a needle, or a buccal swab will be collected by rubbing the inside of your cheek. The process is quick and minimally invasive.
Report Delivery
Apply pressure to the blood draw site to prevent bruising. For buccal swabs, avoid eating or drinking for 30 minutes before collection. Resume normal activities immediately.
Timeline: 10-12 days from sample collection
Patient Instructions
About This Test
Who Should Get This Test
This test is performed to determine the HLA-DQB1 type for assessing compatibility in organ and bone marrow transplants, aiding in the diagnosis of autoimmune diseases, and supporting genetic research and susceptibility studies. It helps clinicians make informed decisions regarding transplant matching and disease management.
How to Prepare
- For blood: Collect 4 mL (min 3 mL) in Lavender Top (EDTA) tube or 6 mL (min 3 mL) in Yellow Top (ACD) tube
- For buccal swab: Collect in a sterile container
- Ship refrigerated; DO NOT FREEZE
- Label samples with patient details and test information
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"HLA DQB1 typing is essential for ensuring compatibility in organ and bone marrow transplants and for evaluating autoimmune conditions. Consult a specialist for personalized medical advice based on test results."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed, clotted, or insufficient sample volume
- Incorrect sample type or container
- Improper labeling or missing patient information
- Sample stored frozen or at room temperature beyond stability
Understanding Your Results
Consult a doctor if results indicate a high-risk allele for autoimmune disease, before transplant procedures, or if you have a family history of HLA-related disorders. Genetic counseling is recommended for understanding results and planning.
Limitations
- ⚠May not detect rare or novel alleles not included in reference databases
- ⚠Excludes alleles that are not expressed as cell surface proteins, potentially limiting interpretation
- ⚠Results require clinical correlation and should not be used in isolation for diagnosis
- ⚠Test accuracy depends on sample quality and adherence to collection protocols
Risks & Considerations
- ●Minor bruising or pain at the blood draw site
- ●Very low risk of infection at the collection site
- ●For buccal swabs, minimal risk of discomfort
Interfering Factors
- ●Sample contamination during collection or handling
- ●Improper storage or transport conditions (e.g., freezing when not allowed)
- ●Recent blood transfusions or stem cell transplants affecting DNA composition
- ●Hemolyzed or clotted blood samples
- ●Use of anticoagulants not specified in instructions
Compare With Similar Tests
| Test | HLA DNA High Resolution Typing - DQB1 Locus Test | HLA DNA Low Resolution Typing | HLA-A Typing | Serological HLA Typing |
|---|---|---|---|---|
| Comparison | HLA DNA High Resolution Typing - DQB1 Locus Test |
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