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DNA Labs India

HLA - DR3 (DRB1*03) Test

DNA Labs India | ISO 9001:2015 Certified

HLA - DR3 (DRB1*03) Test

Also known as: HLA-DR3 Test, DRB1*03 Typing

HLA - DR3 (DRB1*03) Test test available at DNA Labs India for ₹6,000. Uses Reverse SSOP - Luminex on Whole blood samples. Results in 10-12 days. Free home collection in 300+ cities across India.

Diagnostic🏠 Home Collection

🩺 Medically Reviewed By

Overview

To diagnose autoimmune diseases by detecting the presence of HLA-DR3 (DRB1*03) protein, which is associated with increased risk for conditions like celiac disease and lupus.

Test Code
796
Price
₹6,000
Sample Type
Whole blood
Result Time
10-12 days
Fasting Required
No
Method
Reverse SSOP - Luminex
Step 1

Sample Collection

No special preparation required.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be collected via venipuncture.

Step 3

Report Delivery

No specific aftercare required; normal activities can be resumed.

Timeline: 10-12 days

Patient Instructions

1
Before the Test:No preparation required.
2
During the Test:Blood sample collection.
3
After the Test:No restrictions.

About This Test

Who Should Get This Test

To diagnose autoimmune diseases by detecting the presence of HLA-DR3 (DRB1*03) protein, which is associated with increased risk for conditions like celiac disease and lupus.

How to Prepare

  • Collect 4 mL whole blood in a Lavender Top (EDTA) tube or 6 mL in a Yellow Top (ACD) tube.
  • Ship refrigerated. Do not freeze.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This test identifies the presence of HLA-DR3 protein, which is associated with an increased risk of autoimmune diseases. It aids in diagnosis and management for conditions like celiac disease and lupus."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole blood
Sample Volume3 mL minimum
ContainerLavender Top (EDTA) tube or Yellow Top (ACD) tube
Collection MethodVenipuncture

Sample Stability

Refrigerator: 96 hours
Sample Rejection Criteria:
  • Samples not collected in specified tubes
  • Samples not refrigerated appropriately

Understanding Your Results

The test detects the presence of HLA-DR3 (DRB1*03) antigen. A positive result indicates the presence of this antigen, which is associated with increased risk for certain autoimmune conditions.
Positive: Associated with Gluten sensitive enteropathy, Dermatitis herpetiformis, Sub-acute cutaneous LE, Addison's disease, and Sjogren’s syndrome.
Negative: Absence of HLA-DR3 antigen.
⚠️ When to Consult a Doctor:

If you have autoimmune symptoms or a family history of autoimmune diseases, consult a doctor for evaluation and testing.

Frequently Asked Questions

What is the HLA - DR3 (DRB1*03) Test?
The HLA - DR3 (DRB1*03) test is a blood test that detects the presence of the HLA-DR3 antigen, a protein linked to increased risk of autoimmune diseases.
What is the cost of the HLA - DR3 Test at DNA Labs India?
The cost of the HLA - DR3 test at DNA Labs India is INR 6000, with free home sample collection available.
What are the symptoms of autoimmune diseases that may require this test?
Common symptoms include fatigue, fever, joint pain, rashes, difficulty concentrating, weight loss or gain, and hair loss.
How is the HLA - DR3 test performed?
It is a simple blood test where a small sample is collected and analyzed using the Reverse SSOP - Luminex method.
Why is the HLA - DR3 test necessary?
It helps diagnose autoimmune diseases in individuals with symptoms or family history, aiding in early detection and treatment.
What diseases are associated with HLA-DR3 positivity?
Positivity is associated with conditions like gluten sensitive enteropathy, dermatitis herpetiformis, sub-acute cutaneous LE, Addison's disease, and Sjogren’s syndrome.
What sample is required for the test?
A whole blood sample: 4 mL in an EDTA tube or 6 mL in an ACD tube.
Is fasting required before the test?
No, no special preparation or fasting is required.
How long does it take to get the test reports?
Reports are typically available within 10-12 days after sample collection.
Is home sample collection available for this test?
Yes, free home sample collection is available for online bookings across India.
What does a positive HLA-DR3 result mean?
A positive result indicates the presence of HLA-DR3 antigen, which may increase the risk of certain autoimmune diseases.
Who should consider getting the HLA-DR3 test?
Individuals experiencing autoimmune symptoms or with a family history of autoimmune diseases should consider this test.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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