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TNFAIP3 Gene Rheumatoid arthritis, TNFAIP3 related NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

TNFAIP3 Gene Rheumatoid arthritis, TNFAIP3 related NGS Genetic Test

Short Name: TNFAIP3 Gene RA NGS Test

Also known as: A20 Gene Test, TNFAIP3 Mutation Analysis, Rheumatoid Arthritis Genetic Test

TNFAIP3 Gene Rheumatoid arthritis, TNFAIP3 related NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

🩺 Medically Reviewed By

Overview

To identify mutations in the TNFAIP3 gene associated with rheumatoid arthritis for early diagnosis, risk assessment, and personalized treatment strategies.

Test Code
2467
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Provide clinical history of the patient and undergo a genetic counseling session to draw a pedigree chart of family members affected with rheumatoid arthritis.

Step 2

Laboratory Analysis

Your sample is analyzed using NGS Technology in our laboratory.

Step 3

Report Delivery

A certified pathologist reviews and signs your report. You receive it as a secure PDF via email and WhatsApp.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Provide clinical history and undergo genetic counseling to assess family history and symptoms.
2
During the Test:Sample collection via blood draw or other specified methods.
3
After the Test:Wait for report delivery in 3-4 weeks; discuss results with a healthcare provider.

About This Test

Who Should Get This Test

To identify mutations in the TNFAIP3 gene associated with rheumatoid arthritis for early diagnosis, risk assessment, and personalized treatment strategies.

How to Prepare

  • Blood sample: Collect via venipuncture in EDTA tube.
  • Extracted DNA: Ensure proper handling and storage.
  • FTA Card: Use one drop of blood on the card as per instructions.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This test aids in early diagnosis and personalized management of rheumatoid arthritis by identifying genetic predispositions through TNFAIP3 gene analysis."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card

Understanding Your Results

Results indicate the presence or absence of mutations in the TNFAIP3 gene. A positive result suggests increased genetic risk for rheumatoid arthritis, while a negative result indicates no detected mutations. Consult a healthcare professional for comprehensive interpretation.
📊

Negative

No pathogenic TNFAIP3 mutations detected. Genetic risk for RA is not elevated based on this gene, but clinical symptoms should be evaluated.

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Positive

Pathogenic TNFAIP3 mutation detected. This indicates increased genetic susceptibility to rheumatoid arthritis. Further clinical assessment and monitoring are recommended.

📊

Variant of Unknown Significance (VUS)

A genetic variant was found, but its clinical significance is unclear. Genetic counseling and follow-up testing may be advised.

⚠️ When to Consult a Doctor:

If you experience persistent joint pain, stiffness, or swelling, or have a family history of rheumatoid arthritis, consult a rheumatologist or genetic counselor for evaluation and potential testing.

Limitations

  • Test may not detect all genetic variants; clinical correlation is essential.
  • Results should be interpreted in conjunction with clinical history and other diagnostic tests.

Risks & Considerations

  • Minimal risk from blood draw, such as bruising or infection.
  • Potential psychological impact of genetic results; genetic counseling is recommended.

Frequently Asked Questions

What is the TNFAIP3 gene?
The TNFAIP3 gene, also known as A20, produces a protein that regulates the immune system and prevents excessive inflammation. Mutations in this gene are linked to rheumatoid arthritis.
How is the TNFAIP3 Gene NGS Genetic Test performed?
The test uses Next Generation Sequencing (NGS) technology to analyze DNA from a blood sample, extracted DNA, or a blood drop on an FTA card for mutations in the TNFAIP3 gene.
Who should consider this genetic test?
Individuals with a family history of rheumatoid arthritis, symptoms of joint inflammation, or those seeking genetic risk assessment for autoimmune disorders.
What does a positive test result mean?
A positive result indicates a pathogenic mutation in the TNFAIP3 gene, suggesting increased genetic susceptibility to rheumatoid arthritis. Clinical correlation and further evaluation are recommended.
What is the cost of the TNFAIP3 Gene NGS Genetic Test in India?
The test costs INR 20,000 at DNA Labs India, with free home sample collection available across many cities.
How long does it take to get the test results?
Results are typically available within 3 to 4 weeks after sample collection.
Is fasting required for this test?
No, fasting is not required for the TNFAIP3 Gene NGS Genetic Test.
Can this test diagnose rheumatoid arthritis definitively?
No, this test identifies genetic risk factors. Diagnosis of rheumatoid arthritis requires clinical evaluation, blood tests, and imaging studies.
What sample types are accepted for the test?
Blood, extracted DNA, or one drop of blood on an FTA card are accepted sample types.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across India.
What should I do before getting tested?
Provide your clinical history and undergo a genetic counseling session to draw a pedigree chart of family members affected with rheumatoid arthritis.
How can I interpret my test results?
Results should be interpreted by a healthcare professional or genetic counselor. A negative result means no mutation detected, while a positive result indicates genetic risk.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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