IGVH Mutation Load Test
Also known as: IGVH Mutation Analysis, Immunoglobulin Heavy Chain Variable Region Mutation Test
IGVH Mutation Load Test test available at DNA Labs India for ₹7,500. Uses Sanger Sequencing on Bone marrow or Peripheral blood samples. Results in 7-8 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the IGVH Mutation Load Test is to assess the mutation status of the IGVH gene, which is critical for diagnosing and prognosing chronic lymphocytic leukemia (CLL) and other lymphoid malignancies. High mutation load is often associated with a better prognosis, while low mutation load may indicate a more aggressive disease course. This test aids in treatment decision-making and patient management.
- Test Code
- 3054
- Price
- ₹7,500
- Sample Type
- Bone marrow or Peripheral blood
- Result Time
- 7-8 days
- Fasting Required
- No
- Method
- Sanger Sequencing
Sample Collection
A doctor's prescription is required for the IGVH Mutation Load Test, except in cases of surgery, pregnancy, or planned travel abroad.
Method: Venipuncture for peripheral blood; Bone marrow aspiration for bone marrow sample
Laboratory Analysis
A blood sample will be drawn from a vein in your arm, or a bone marrow sample will be aspirated from the hip bone under sterile conditions by a trained professional.
Report Delivery
Apply pressure to the puncture site with a cotton ball to prevent bleeding. You may resume normal activities immediately.
Timeline: 7-8 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the IGVH Mutation Load Test is to assess the mutation status of the IGVH gene, which is critical for diagnosing and prognosing chronic lymphocytic leukemia (CLL) and other lymphoid malignancies. High mutation load is often associated with a better prognosis, while low mutation load may indicate a more aggressive disease course. This test aids in treatment decision-making and patient management.
How to Prepare
- Sample must be transported immediately to the laboratory to ensure accuracy.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is crucial for determining the prognosis and treatment plan for patients with chronic lymphocytic leukemia and other lymphoid malignancies."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Understanding Your Results
If you experience symptoms such as unexplained fever, persistent fatigue, unintentional weight loss, swollen lymph nodes, or easy bruising and bleeding, consult a healthcare professional promptly.
Risks & Considerations
- ●Minor bruising or discomfort at the puncture site
- ●Rare risk of infection or excessive bleeding
Frequently Asked Questions
What is the IGVH Mutation Load Test?
Why is the IGVH Mutation Load Test performed?
How is the IGVH Mutation Load Test done?
What is the cost of the IGVH Mutation Load Test at DNA Labs India?
Is home sample collection available for this test?
How long does it take to get the results?
What do the results of the IGVH Mutation Load Test indicate?
Is a doctor's prescription required for this test?
What are the symptoms that may indicate the need for this test?
Are there any risks associated with the test?
How should I prepare for the IGVH Mutation Load Test?
Can this test be used for diagnosing other conditions besides leukemia and lymphoma?
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