Immunohistochemistry Beta-Catenin Test
Short Name: IHC Beta-Catenin Test
Also known as: Beta-Catenin Immunohistochemistry, IHC for Beta-Catenin
Immunohistochemistry Beta-Catenin Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Reports are available within 5-7 days from sample receipt at the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To identify beta-catenin protein expression in tissue samples for diagnosing cancers and soft tissue tumors, including desmoid-type fibromatosis, and to differentiate spindle cell lesions.
- Test Code
- 882
- Price
- ₹3,500
- Sample Type
- Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Result Time
- Reports are available within 5-7 days from sample receipt at the laboratory.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the Histopathology report, site of biopsy, and clinical history as pre-test information.
Method: Biopsy or Surgery
Laboratory Analysis
Tissue sample is collected via biopsy or surgery under sterile conditions and preserved in formalin.
Report Delivery
Sample is shipped at room temperature to the laboratory for processing and analysis.
Timeline: Reports are available within 5-7 days from sample receipt at the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
To identify beta-catenin protein expression in tissue samples for diagnosing cancers and soft tissue tumors, including desmoid-type fibromatosis, and to differentiate spindle cell lesions.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Ship at room temperature
- Include a copy of the Histopathology report, site of biopsy, and clinical history
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is essential for detecting beta-catenin abnormalities in tumors, aiding in accurate cancer diagnosis and targeted treatment planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Inadequate tissue sample
- Improperly fixed tissue
- Missing clinical information or Histopathology report
Understanding Your Results
Negative
No aberrant nuclear staining observed, suggesting absence of beta-catenin mutation in the tissue
Positive
Aberrant nuclear staining present, indicating beta-catenin mutation associated with tumors like desmoid fibromatosis
If you experience symptoms such as abnormal growths, abdominal pain, blood in stool, or if the test results are abnormal, consult an oncologist or pathologist immediately for further evaluation.
Limitations
- ⚠Cannot distinguish between benign and malignant tumors solely based on this test
- ⚠Requires expert interpretation by a pathologist
- ⚠False negatives or positives may occur due to technical issues
Risks & Considerations
- ●Minimal risks associated with biopsy collection, such as infection or bleeding
- ●Standard procedural risks are low when performed by qualified professionals
Interfering Factors
- ●Improper tissue fixation
- ●Delayed sample processing
- ●Contamination during handling
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