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Immunohistochemistry PAX-5 Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry PAX-5 Test

Short Name: IHC PAX-5

Also known as: PAX-5 Immunohistochemistry, IHC PAX-5 Test

Immunohistochemistry PAX-5 Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor Tissue samples. Results in Report delivery within 5 to 7 days after sample receipt.. Free home collection in 300+ cities across India.

Oncologist, Pathologist🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To detect PAX-5 protein expression in tissue samples for the diagnosis and classification of B-cell malignancies, including lymphoma and leukemia.

Test Code
1023
Price
₹3,500
Sample Type
Tumor Tissue
Result Time
Report delivery within 5 to 7 days after sample receipt.
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Provide a copy of the histopathology report, site of biopsy, and clinical history. Ensure the tissue sample is properly fixed in 10% formal-saline or as a formalin fixed paraffin embedded block.

Method: Biopsy or Surgical Excision

Step 2

Laboratory Analysis

The sample is collected via biopsy or surgical excision from the affected area, such as a lymph node, under sterile conditions.

Step 3

Report Delivery

Ship the sample at room temperature to the laboratory. Avoid delays to maintain sample integrity.

Timeline: Report delivery within 5 to 7 days after sample receipt.

Patient Instructions

1
Before the Test:Ensure all required documents, including histopathology report and clinical history, are provided. No special preparation needed from the patient.
2
During the Test:The tissue sample is processed, stained with PAX-5 antibodies, and examined microscopically by a pathologist.
3
After the Test:Results are compiled into a report. Discuss findings with your doctor for next steps.

About This Test

Who Should Get This Test

To detect PAX-5 protein expression in tissue samples for the diagnosis and classification of B-cell malignancies, including lymphoma and leukemia.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block.
  • Ship at room temperature.
  • Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"The PAX-5 test is essential for identifying B-cell malignancies, aiding in accurate diagnosis and personalized treatment planning for lymphoma and leukemia patients."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor Tissue
Container10% Formal-saline or Formalin fixed paraffin embedded block
Collection MethodBiopsy or Surgical Excision

Sample Stability

Stable at room temperature when fixed in formalin
Can be stored for several days if properly processed
Sample Rejection Criteria:
  • Insufficient sample size
  • Improper fixation or labeling
  • Missing clinical information

Understanding Your Results

Results indicate the presence or absence of PAX-5 protein in the tissue sample. Positive staining suggests B-cell lineage, aiding in the diagnosis of B-cell malignancies.
Positive PAX-5: Nuclear staining in B-cells, consistent with B-cell lymphoma or leukemia.
Negative PAX-5: Absence of staining, which may indicate non-B-cell malignancies or other conditions.
Results should be correlated with clinical history and other diagnostic tests.
⚠️ When to Consult a Doctor:

If symptoms such as swollen lymph nodes, fever, or weight loss persist, or if test results are abnormal, consult an oncologist or hematologist for further evaluation and management.

Limitations

  • ⚠Limited to detecting B-cell lineage markers
  • ⚠Requires adequate tissue sample
  • ⚠Interpretation may vary based on tissue type and fixation

Risks & Considerations

  • ●Minimal risks from biopsy procedure, such as infection or bleeding
  • ●No direct risks from the immunohistochemistry test itself

Interfering Factors

  • ●Improper tissue fixation
  • ●Delay in sample processing
  • ●Use of incorrect antibodies

Compare With Similar Tests

TestImmunohistochemistry PAX-5 TestImmunohistochemistry CD20Flow Cytometry
ComparisonImmunohistochemistry PAX-5 TestSimilar IHC test for B-cell markers; PAX-5 is often used alongside CD20 for comprehensive diagnosis.Used to analyze cell populations; IHC PAX-5 provides spatial context in tissue sections.

Frequently Asked Questions

What is the Immunohistochemistry PAX-5 Test?
It is a diagnostic test that detects PAX-5 protein in tissue samples to identify B-cell malignancies like lymphoma and leukemia.
Why is this test recommended?
It is recommended for diagnosing B-cell cancers, especially when symptoms such as swollen lymph nodes or unexplained weight loss are present.
What does a positive PAX-5 result mean?
A positive result indicates the presence of PAX-5 protein, suggesting B-cell lineage and supporting a diagnosis of B-cell lymphoma or leukemia.
How is the sample collected for this test?
The sample is a tumor tissue obtained via biopsy, fixed in formalin or formal-saline, and sent to the laboratory.
Is fasting required for the Immunohistochemistry PAX-5 Test?
No, fasting is not required as it is a tissue-based test, not a blood test.
How long does it take to get results?
Results are typically available within 5 to 7 days after the sample is received.
What are the risks of the test?
The test itself has minimal risks; any risks are associated with the biopsy procedure, such as infection or bleeding.
Can this test diagnose all types of lymphoma?
It is specific for B-cell lymphomas; other lymphomas may require different markers or tests.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for this test across many cities in India.
How should I prepare for the test?
Provide necessary documents like histopathology report and clinical history. No patient preparation is needed.
What if the test is negative but symptoms persist?
Consult your doctor; additional tests or evaluations may be needed to determine the cause of symptoms.
Is the test covered by insurance?
Coverage depends on your insurance plan; check with your provider for details.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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