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Immunohistochemistry Epithelial Membrane Antigen (EMA) Test

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Immunohistochemistry Epithelial Membrane Antigen (EMA) Test

Short Name: EMA IHC Test

Also known as: EMA Test, Epithelial Membrane Antigen Test

Immunohistochemistry Epithelial Membrane Antigen (EMA) Test test available at DNA Labs India for ₹2,059. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Reports are typically available within 5-7 days after sample collection.. Free home collection in 300+ cities across India.

Diagnostic🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

To detect the presence of Epithelial Membrane Antigen (EMA) in tissue samples, aiding in the diagnosis of epithelial-derived cancers and other neoplastic conditions.

Test Code
937
Price
₹2,059
Sample Type
Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
Result Time
Reports are typically available within 5-7 days after sample collection.
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Provide a copy of the histopathology report, site of biopsy, and clinical history.

Method: Tissue biopsy or surgical resection

Step 2

Laboratory Analysis

Tissue sample collected via biopsy or surgical procedure under local anesthesia.

Step 3

Report Delivery

Sample is fixed and sent to the laboratory for immunohistochemical analysis.

Timeline: Reports are typically available within 5-7 days after sample collection.

Patient Instructions

1
Before the Test:No specific preparation; provide necessary documentation as per collection instructions.
2
During the Test:Biopsy procedure performed by a healthcare professional.
3
After the Test:Sample processed in lab; results available after 5-7 days.

About This Test

Who Should Get This Test

To detect the presence of Epithelial Membrane Antigen (EMA) in tissue samples, aiding in the diagnosis of epithelial-derived cancers and other neoplastic conditions.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block.
  • Ship at room temperature.
  • Provide a copy of the histopathology report, site of biopsy, and clinical history.

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"The EMA test is crucial for identifying epithelial-derived cancers, aiding in accurate diagnosis and treatment planning to improve patient outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
Sample VolumeAs per biopsy size
ContainerFormalin container or paraffin block
Collection MethodTissue biopsy or surgical resection

Sample Stability

Stable at room temperature for 24 hours
Long-term storage in paraffin block
Sample Rejection Criteria:
  • Improperly labeled sample
  • Insufficient tissue
  • Contaminated sample

Understanding Your Results

The presence of EMA staining indicates the expression of Epithelial Membrane Antigen, commonly associated with epithelial cells and their neoplasms.
Positive EMA staining: Suggests epithelial origin, often seen in carcinomas.
Negative EMA staining: May indicate non-epithelial origin or lack of EMA expression.
Intensity and pattern of staining are reported by the pathologist.
Correlation with other markers and clinical findings is essential for diagnosis.
⚠️ When to Consult a Doctor:

Consult an oncologist or your healthcare provider if your test results are positive or if symptoms persist after a negative test.

Limitations

  • ⚠Results may vary based on tissue quality
  • ⚠False positives/negatives possible
  • ⚠Interpretation requires expert pathologist

Risks & Considerations

  • ●Minimal risks from biopsy: infection, bleeding, or discomfort at the site.

Interfering Factors

  • ●Poor tissue fixation
  • ●Antibody degradation
  • ●Incorrect sample handling

Frequently Asked Questions

What is the Immunohistochemistry EMA test?
The EMA test detects Epithelial Membrane Antigen in tissue samples using immunohistochemistry, helping diagnose cancers like breast, lung, and ovarian cancer.
Why is the EMA test performed?
It is performed to identify epithelial-derived neoplasms, differentiate between benign and malignant tissues, and assist in cancer diagnosis and staging.
What sample is required for the EMA test?
A tumor tissue sample collected via biopsy or surgery, fixed in formalin or as a paraffin block.
Is fasting required for the EMA test?
No, fasting is not required as it is a tissue-based test.
How much does the EMA test cost at DNA Labs India?
The test costs INR 2059.2, with home sample collection available.
How long does it take to get the EMA test results?
Results are typically available within 5-7 days after sample collection.
Is home sample collection available for the EMA test?
Yes, DNA Labs India offers free home sample collection for this test across many cities in India.
What does a positive EMA test result mean?
A positive result indicates the presence of EMA, suggesting an epithelial-derived neoplasm, which may be malignant.
Are there any risks associated with the EMA test?
The risks are minimal and related to the biopsy procedure, such as infection or bleeding.
How accurate is the EMA test?
The test is highly accurate when performed on properly collected and processed samples, but interpretation by an expert pathologist is crucial.
Can I undergo the EMA test if I have other medical conditions?
Yes, but inform your doctor about any conditions or medications that might affect the sample or interpretation.
How do I prepare for the EMA test?
No special preparation is needed; provide the required documentation like histopathology report and clinical history.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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