Immunohistochemistry Kappa Light Chains Test
Short Name: IHC Kappa Light Chains
Also known as: IHC Kappa Light Chains, Kappa Light Chain Immunohistochemistry
Immunohistochemistry Kappa Light Chains Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue samples. Results in Report available within 5-7 days after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The IHC Kappa Light Chains test is used to detect the presence of kappa light chains in tissue samples, helping diagnose and monitor conditions such as B-cell neoplasms, plasma cell disorders, and amyloidosis. It establishes clonality and supports differential diagnosis in oncology and immunology.
- Test Code
- 1009
- Price
- ₹3,500
- Sample Type
- Tumor tissue
- Result Time
- Report available within 5-7 days after sample receipt.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the histopathology report, site of biopsy, and clinical history. No fasting required.
Method: Biopsy or Surgery
Laboratory Analysis
Sample collected via biopsy or surgery; tissue fixed appropriately in formalin.
Report Delivery
Sample sent to laboratory for processing; report generated after analysis by pathologist.
Timeline: Report available within 5-7 days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The IHC Kappa Light Chains test is used to detect the presence of kappa light chains in tissue samples, helping diagnose and monitor conditions such as B-cell neoplasms, plasma cell disorders, and amyloidosis. It establishes clonality and supports differential diagnosis in oncology and immunology.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Ship at room temperature to prevent degradation
- Include histopathology report, biopsy site, and clinical history with the sample
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is crucial for diagnosing clonal B-cell disorders and amyloidosis, aiding in accurate treatment planning and monitoring."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Inadequate sample size or quality
- Incorrect fixation or handling
- Missing clinical information or histopathology report
Understanding Your Results
Positive
Presence of kappa light chains indicates clonal B-cell disorder; further tests recommended to confirm diagnosis and subtype.
Negative
Absence of kappa light chains; consider lambda light chain testing or other causes if clinically indicated.
Consult your doctor if you experience symptoms like unexplained weight loss, fatigue, swelling, or bone pain, or if the test results are abnormal for further evaluation and management.
Limitations
- ⚠False negatives possible if target antigen is lost or degraded
- ⚠Results require correlation with clinical and histopathological findings
- ⚠Not a standalone diagnostic tool; may need additional tests for confirmation
Risks & Considerations
- ●Minimal risks associated with biopsy procedure, such as bleeding or infection
- ●Potential for false results, though rare with standardized protocols
Interfering Factors
- ●Inadequate tissue fixation
- ●Antibody cross-reactivity or degradation
- ●Technical errors in processing or staining
Compare With Similar Tests
| Test | Immunohistochemistry Kappa Light Chains Test | Immunohistochemistry Lambda Light Chains Test | Serum Protein Electrophoresis | Bone Marrow Biopsy |
|---|---|---|---|---|
| Comparison | Immunohistochemistry Kappa Light Chains Test |
Frequently Asked Questions
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Is home sample collection available?
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