Immunohistochemistry PLAP Test
Short Name: PLAP Test
Also known as: Placental Alkaline Phosphatase Test, PLAP Immunohistochemistry
Immunohistochemistry PLAP Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Reports are typically available within 5-7 business days after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the Immunohistochemistry PLAP Test is to detect the presence of Placental Alkaline Phosphatase (PLAP) in tissue samples, aiding in the diagnosis and confirmation of germ cell tumors. It helps oncologists and pathologists identify specific cancer types, assess tumor characteristics, and plan appropriate treatment strategies.
- Test Code
- 1034
- Price
- ₹3,500
- Sample Type
- Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Result Time
- Reports are typically available within 5-7 business days after sample receipt.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the Histopathology report, site of biopsy, and clinical history. Ensure tissue sample is properly collected and preserved.
Method: Tissue biopsy collection
Laboratory Analysis
Tumor tissue is collected via biopsy or surgical excision and placed in appropriate fixative.
Report Delivery
Store sample at room temperature and ship to the laboratory promptly. Avoid delays to maintain sample integrity.
Timeline: Reports are typically available within 5-7 business days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Immunohistochemistry PLAP Test is to detect the presence of Placental Alkaline Phosphatase (PLAP) in tissue samples, aiding in the diagnosis and confirmation of germ cell tumors. It helps oncologists and pathologists identify specific cancer types, assess tumor characteristics, and plan appropriate treatment strategies.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Ship at room temperature without freezing
- Include a copy of the Histopathology report, site of biopsy, and clinical history
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"The Immunohistochemistry PLAP Test is essential for accurate detection of germ cell tumors, aiding in timely diagnosis and treatment planning for cancer patients."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Improperly fixed or preserved tissue
- Insufficient sample quantity
- Missing clinical history or biopsy site information
- Contaminated or degraded samples
Understanding Your Results
Positive PLAP Staining
Suggests germ cell tumor, such as seminoma, embryonal carcinoma, or yolk sac tumor. Correlation with clinical and histopathological findings is recommended.
Negative PLAP Staining
PLAP expression not detected; may indicate non-germ cell tumors or other benign conditions. Further diagnostic tests may be needed.
Weak or Focal Staining
Inconclusive; recommend repeat testing or additional immunohistochemical markers for confirmation.
Consult a doctor if you experience symptoms like persistent pain, lumps, hormonal changes, or if test results are positive or inconclusive for further evaluation and management.
Limitations
- ⚠May show positive staining in some epithelial tumors like serous carcinoma
- ⚠Requires accurate histopathological correlation
- ⚠Not a standalone diagnostic tool; should be used with other tests
- ⚠False negatives possible if PLAP expression is low or absent
Risks & Considerations
- ●No significant risks from the test itself, as it involves analysis of already collected tissue
- ●Risks associated with biopsy collection, such as infection or bleeding, are separate from the test procedure
Interfering Factors
- ●Poor tissue fixation or preservation
- ●Incorrect sample handling or contamination
- ●Inadequate tissue quantity or quality
- ●Technical errors in immunohistochemical staining procedure
Frequently Asked Questions
What is the Immunohistochemistry PLAP Test?
What is the cost of the PLAP Test in India?
What are the common symptoms of germ cell tumors?
How is the PLAP Test performed?
What sample is required for the PLAP Test?
How long does it take to get PLAP Test results?
Is home collection available for the PLAP Test?
What does a positive PLAP Test result mean?
Are there any risks associated with the PLAP Test?
Can the PLAP Test be used for other cancers?
How should I prepare for the PLAP Test?
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