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Immunohistochemistry Thyroglobulin (TG) Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry Thyroglobulin (TG) Test

Short Name: IHC Thyroglobulin Test

Also known as: Thyroglobulin IHC Test, TG Immunohistochemistry, IHC TG Test

Immunohistochemistry Thyroglobulin (TG) Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Reports are typically available within 5-7 days after sample receipt.. Free home collection in 300+ cities across India.

Oncologist, PathologistAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The purpose of the Immunohistochemistry Thyroglobulin (TG) test is to detect thyroglobulin in thyroid tissues, aiding in the diagnosis of thyroid cancer and monitoring treatment efficacy. It helps identify metastatic sites and guides therapeutic decisions.

Test Code
1047
Price
₹3,500
Sample Type
Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
Result Time
Reports are typically available within 5-7 days after sample receipt.
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Provide a copy of the histopathology report, site of biopsy, and clinical history.

Method: Biopsy

Step 2

Laboratory Analysis

Tissue biopsy procedure performed by a healthcare professional, usually as an outpatient.

Step 3

Report Delivery

Sample is preserved and shipped to the laboratory for processing.

Timeline: Reports are typically available within 5-7 days after sample receipt.

Patient Instructions

1
Before the Test:No specific preparation required, but ensure all relevant medical documents are provided.
2
During the Test:Biopsy procedure is typically quick and performed under local anesthesia in a clinical setting.
3
After the Test:Mild discomfort may occur; follow post-biopsy care instructions from the healthcare provider.

About This Test

Who Should Get This Test

The purpose of the Immunohistochemistry Thyroglobulin (TG) test is to detect thyroglobulin in thyroid tissues, aiding in the diagnosis of thyroid cancer and monitoring treatment efficacy. It helps identify metastatic sites and guides therapeutic decisions.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
  • Ship at room temperature
  • Provide a copy of the histopathology report, site of biopsy, and clinical history

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This test is crucial for diagnosing thyroid cancer and monitoring treatment response, helping to guide clinical decisions."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
Sample VolumeAs required for tissue biopsy
Container10% Formal-saline or Formalin fixed paraffin embedded block
Collection MethodBiopsy

Sample Stability

Stable at room temperature for short-term transport
Best preserved in formalin for long-term storage
Sample Rejection Criteria:
  • Inadequate sample size
  • Improper fixation or container
  • Missing clinical information or documentation

Understanding Your Results

Results indicate the presence or absence of thyroglobulin in thyroid tissues, which helps in diagnosing thyroid cancer and assessing treatment response.
Positive result suggests thyroglobulin presence, indicating thyroid origin, often associated with thyroid cancer
Negative result may require further investigation or indicate absence of cancer
Results must be interpreted in context with clinical findings and other diagnostic tests
⚠️ When to Consult a Doctor:

Consult an oncologist or endocrinologist if symptoms persist, test results are abnormal, or for follow-up care based on test outcomes.

Limitations

  • ⚠May not distinguish benign from malignant conditions in all cases
  • ⚠Requires interpretation by an experienced pathologist
  • ⚠Results should be correlated with clinical history and other tests

Risks & Considerations

  • ●Biopsy-related risks: bleeding, infection, or pain at the biopsy site
  • ●Potential for false positive or negative results requiring additional testing

Interfering Factors

  • ●Tissue fixation quality
  • ●Sample handling and preservation
  • ●Presence of non-thyroid tissues

Compare With Similar Tests

TestImmunohistochemistry Thyroglobulin (TG) Test
ComparisonImmunohistochemistry Thyroglobulin (TG) TestImaging test that detects structural abnormalities, complementary to IHC TG testMeasures thyroglobulin levels in blood, used for monitoring, whereas IHC TG test examines tissueProvides detailed images for staging cancer, often used alongside IHC for comprehensive diagnosisDetects metabolic activity of cancer cells, useful for metastatic evaluation

Frequently Asked Questions

What is the Immunohistochemistry Thyroglobulin (TG) test?
It is a diagnostic test that detects thyroglobulin protein in thyroid tissues using immunohistochemistry, primarily for diagnosing thyroid cancer.
Why is this test performed?
To diagnose thyroid cancer, monitor treatment effectiveness, and evaluate metastatic sites, especially in cases of thyroid neoplasms.
What is the cost of the test in India?
The cost is approximately INR 3500, which may vary slightly by location and laboratory.
What sample is required for the test?
A tumor tissue sample from a biopsy, submitted in 10% Formal-saline or as a Formalin fixed paraffin embedded block.
Is fasting required before the test?
No, fasting is not required for this test.
How long does it take to get the results?
Results are typically available within 5-7 days after sample receipt.
What symptoms may indicate the need for this test?
Symptoms include neck pain, difficulty swallowing, hoarseness, swollen lymph nodes, and changes in voice quality.
Are there any risks associated with the test?
The main risks are related to the biopsy procedure, such as bleeding or infection, and potential for false results requiring further testing.
Can this test be done at home?
Sample collection for biopsy is typically performed in a clinical setting, but home sample collection for online bookings is available in many cities.
How should I prepare for the test?
No special preparation is needed, but provide a copy of your histopathology report, biopsy site, and clinical history.
What if the test result is positive?
A positive result indicates the presence of thyroglobulin, suggesting thyroid cancer origin, and further tests may be recommended for staging and treatment planning.
Is the test covered by insurance?
Coverage depends on your insurance policy; it is not universally covered, so check with your provider.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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