Immunohistochemistry Thyroid Stimulating Hormone (TSH) Test
Short Name: IHC TSH Test
Also known as: IHC for TSH, TSH Immunohistochemistry
Immunohistochemistry Thyroid Stimulating Hormone (TSH) Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue samples. Results in Reports typically available within 5-7 days after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of the Immunohistochemistry TSH Test is to detect the presence of Thyroid Stimulating Hormone in tumor tissues to aid in the classification of pituitary adenomas, particularly TSH-secreting adenomas, which are rare and often part of plurihormonal tumors. This test supports accurate diagnosis, guides treatment decisions in oncology, and helps differentiate between various types of pituitary neoplasms.
- Test Code
- 1048
- Price
- ₹3,500
- Sample Type
- Tumor tissue
- Result Time
- Reports typically available within 5-7 days after sample receipt.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Ensure biopsy is performed by a qualified healthcare provider. Provide complete clinical history and prior histopathology reports.
Method: Biopsy collection
Laboratory Analysis
Tumor tissue is collected via biopsy procedure and immediately fixed in 10% formal-saline or processed for paraffin embedding.
Report Delivery
Ship the sample at room temperature to DNA Labs India with all required documentation.
Timeline: Reports typically available within 5-7 days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Immunohistochemistry TSH Test is to detect the presence of Thyroid Stimulating Hormone in tumor tissues to aid in the classification of pituitary adenomas, particularly TSH-secreting adenomas, which are rare and often part of plurihormonal tumors. This test supports accurate diagnosis, guides treatment decisions in oncology, and helps differentiate between various types of pituitary neoplasms.
How to Prepare
- Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block.
- Ship at room temperature.
- Provide a copy of the Histopathology report, Site of biopsy, and Clinical history.
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"Immunohistochemistry for TSH is crucial for accurately classifying pituitary adenomas, guiding treatment decisions, and monitoring therapy outcomes in oncology."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample not fixed properly or in incorrect container
- Missing histopathology report or clinical history
- Tissue sample inadequate for testing
Understanding Your Results
Positive for TSH expression
Suggests TSH-secreting pituitary adenoma; further clinical correlation is recommended.
Negative for TSH expression
TSH not detected; consider other pituitary tumor subtypes or conditions.
Weak staining intensity
May indicate low TSH levels; requires cautious interpretation with clinical context.
Strong staining intensity
Likely high TSH expression; consistent with active TSH-secreting adenoma.
Consult your oncologist or endocrinologist if the test results are positive or inconclusive, especially if experiencing symptoms like headaches, vision changes, or hormonal imbalances.
Limitations
- ⚠Results are qualitative and depend on tissue quality
- ⚠Cannot distinguish between active and inactive TSH forms
- ⚠May not detect low-level expression in small tumor samples
- ⚠Requires correlation with clinical and imaging findings for accurate diagnosis
Risks & Considerations
- ●Risks associated with biopsy procedure, such as infection, bleeding, or discomfort
- ●Minimal risk from sample handling and testing in the lab
Interfering Factors
- ●Improper tissue fixation or processing
- ●Delayed sample submission
- ●Inadequate clinical history or histopathology report
- ●Cross-reactivity with other hormones in immunohistochemistry
Frequently Asked Questions
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