Immunohistochemistry TLE1 (1F5) Test
Short Name: IHC TLE1 (1F5) Test
Also known as: TLE1 Immunohistochemistry Test, IHC TLE1 (1F5)
Immunohistochemistry TLE1 (1F5) Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Reports typically available within 5-7 working days after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the Immunohistochemistry TLE1 (1F5) test is to detect TLE1 protein overexpression, which is a highly sensitive and specific biomarker for diagnosing synovial sarcoma in cases of unclassifiable high-grade sarcomas.
- Test Code
- 1049
- Price
- ₹3,500
- Sample Type
- Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Result Time
- Reports typically available within 5-7 working days after sample receipt.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the histopathology report, site of biopsy, and clinical history.
Method: Tissue biopsy
Laboratory Analysis
Tissue biopsy is collected under sterile conditions from the suspected lesion.
Report Delivery
Sample is preserved in formalin for transport and processing.
Timeline: Reports typically available within 5-7 working days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Immunohistochemistry TLE1 (1F5) test is to detect TLE1 protein overexpression, which is a highly sensitive and specific biomarker for diagnosing synovial sarcoma in cases of unclassifiable high-grade sarcomas.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block.
- Ship at room temperature.
- Provide a copy of the histopathology report, site of biopsy, and clinical history.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"TLE1 immunohistochemistry is a highly sensitive and specific biomarker for synovial sarcoma, aiding in accurate diagnosis and treatment planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Inadequate tissue sample
- Improper fixation or preservation
- Missing clinical information or histopathology report
Understanding Your Results
Positive for TLE1
Supports diagnosis of synovial sarcoma with high sensitivity and specificity.
Negative for TLE1
Less likely synovial sarcoma; consider other soft tissue sarcomas and additional diagnostic tests.
If you experience symptoms such as a persistent lump, pain, or numbness, consult an oncologist or specialist immediately for evaluation and potential testing.
Limitations
- ⚠False positives or negatives may occur
- ⚠Requires skilled pathologist interpretation
- ⚠Not a standalone diagnostic; must be correlated with clinical and histopathological findings
Risks & Considerations
- ●No direct risks to the patient from the test itself; risks are associated with the biopsy procedure, such as infection or bleeding.
Interfering Factors
- ●Poor tissue fixation quality
- ●Inadequate sample handling or transport
- ●Technical artifacts during staining
- ●Subjective interpretation variability
Compare With Similar Tests
| Test | Immunohistochemistry TLE1 (1F5) Test | FISH for SYT-SSX Fusion Gene | Core Needle Biopsy and Histopathology | Immunohistochemistry Panel for Sarcoma |
|---|---|---|---|---|
| Comparison | Immunohistochemistry TLE1 (1F5) Test |
Frequently Asked Questions
What is the Immunohistochemistry TLE1 (1F5) test?
Why is the TLE1 test performed?
What are the symptoms of synovial sarcoma?
How is the sample collected for this test?
Is fasting required for the TLE1 test?
How long does it take to get the results?
What does a positive TLE1 result mean?
Are there any risks associated with the test?
How accurate is the TLE1 immunohistochemistry test?
What other tests are done along with TLE1 for diagnosis?
Is the test covered by insurance?
How can I book the TLE1 test with DNA Labs India?
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