Immunophenotyping by Flow Cytometry IgG Heavy Chain Surface Test
Short Name: IgG Heavy Chain Surface Test
Also known as: Flow Cytometry IgG Surface Test, IgG Heavy Chain Immunophenotyping
Immunophenotyping by Flow Cytometry IgG Heavy Chain Surface Test test available at DNA Labs India for ₹3,500. Uses Flow Cytometry on 3 mL whole blood in EDTA tube and Sodium Heparin tube, or 2 mL bone marrow in Sodium Heparin tube samples. Results in Reports available same day if sample received by 9 am.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the Immunophenotyping by Flow Cytometry IgG Heavy Chain Surface Test is to diagnose and monitor diseases characterized by abnormal B cell activity, such as multiple myeloma and chronic lymphocytic leukemia. It helps in identifying the presence of IgG heavy chain surface markers on cells, which can indicate malignancies or immune disorders, guiding clinical decisions and treatment strategies.
- Test Code
- 1085
- Price
- ₹3,500
- Sample Type
- 3 mL whole blood in EDTA tube and Sodium Heparin tube, or 2 mL bone marrow in Sodium Heparin tube
- Result Time
- Reports available same day if sample received by 9 am.
- Fasting Required
- No
- Method
- Flow Cytometry
Sample Collection
Provide brief clinical history and any relevant medical details on the test request form.
Method: Venipuncture or Bone Marrow Aspiration
Laboratory Analysis
Sample collection via venipuncture or bone marrow aspiration using specified tubes.
Report Delivery
Ship immediately at 18-22°C. Do not refrigerate or freeze. Ensure proper labeling with time, date, and clinical details.
Timeline: Reports available same day if sample received by 9 am.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Immunophenotyping by Flow Cytometry IgG Heavy Chain Surface Test is to diagnose and monitor diseases characterized by abnormal B cell activity, such as multiple myeloma and chronic lymphocytic leukemia. It helps in identifying the presence of IgG heavy chain surface markers on cells, which can indicate malignancies or immune disorders, guiding clinical decisions and treatment strategies.
How to Prepare
- Collect 3 mL whole blood in EDTA tube and 3 mL in Sodium Heparin tube
- OR collect 2 mL bone marrow in Sodium Heparin tube
- Maintain temperature at 18-22°C during transport
- Label tubes with patient details and collection time
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is crucial for early diagnosis and monitoring of hematological cancers like multiple myeloma, aiding in timely treatment decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Incorrect sample type or tube
- Hemolyzed or lipemic samples
- Inadequate volume or improper labeling
- Sample received beyond stability period
Understanding Your Results
Positive for IgG heavy chain expression
May indicate multiple myeloma, CLL, or other B-cell disorders; further evaluation needed.
Negative or normal expression
No significant IgG heavy chain surface markers detected; does not rule out all conditions.
Elevated levels
Suggests active disease or progression; correlate with clinical symptoms and other tests.
Consult your doctor if you experience symptoms like bone pain, fatigue, swollen lymph nodes, or unexplained weight loss, or if results are abnormal.
Limitations
- ⚠May not detect all subtypes of diseases
- ⚠Requires skilled personnel for interpretation
- ⚠False negatives possible in early-stage diseases
Risks & Considerations
- ●Minor bruising or pain at puncture site
- ●Rare risk of infection or excessive bleeding from bone marrow aspiration
Interfering Factors
- ●Hemolyzed or clotted samples
- ●Improper sample storage or transport
- ●Recent blood transfusions
- ●Contamination with other substances
Compare With Similar Tests
| Test | Immunophenotyping by Flow Cytometry IgG Heavy Chain Surface Test | Serum Protein Electrophoresis | Bone Marrow Biopsy | Complete Blood Count (CBC) | Immunophenotyping for Other Markers |
|---|---|---|---|---|---|
| Comparison | Immunophenotyping by Flow Cytometry IgG Heavy Chain Surface Test | Detects abnormal proteins in blood but does not specify cell surface markers. | Provides tissue sample for histological analysis but is more invasive. | Measures blood cell counts but lacks specificity for immunophenotyping. | Similar flow cytometry tests for different surface markers like CD19 or CD20. |
Frequently Asked Questions
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