Immunophenotyping by Flow Cytometry IgM Heavy Chain Cytoplasmic Test
Short Name: IgM Heavy Chain Cytoplasmic Flow Cytometry
Also known as: Cytoplasmic IgM Heavy Chain Immunophenotyping, IgM Heavy Chain Cytoplasmic Flow Cytometry, Flow Cytometry IgM Cytoplasmic Test
Immunophenotyping by Flow Cytometry IgM Heavy Chain Cytoplasmic Test test available at DNA Labs India for ₹3,500. Uses Flow Cytometry on 3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tube AND 3 mL (2 mL min.) whole blood in 1 Green Top (Sodium Heparin) tube OR 2 mL (1 mL min.) Bone marrow in 1 Green Top (Sodium heparin) tube samples. Results in Sample daily by 9 am; report same day.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The test detects cytoplasmic IgM heavy chain expression by flow cytometry to identify clonal B-cell populations and to aid in diagnosis, prognosis, and monitoring of B-cell malignancies such as lymphoma, leukemia, and multiple myeloma. It also serves as a pre-B cell acute lymphoblastic leukemia prognostic and clonal restriction marker.
- Test Code
- 3497
- Price
- ₹3,500
- Sample Type
- 3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tube AND 3 mL (2 mL min.) whole blood in 1 Green Top (Sodium Heparin) tube OR 2 mL (1 mL min.) Bone marrow in 1 Green Top (Sodium heparin) tube
- Result Time
- Sample daily by 9 am; report same day.
- Fasting Required
- No
- Method
- Flow Cytometry
Sample Collection
Give brief clinical history. Specify time, date and clinical details on test request form. No fasting is required.
Method: Venipuncture or bone marrow aspiration
Laboratory Analysis
Collect whole blood in Lavender Top EDTA and Green Top Sodium Heparin tubes or bone marrow in Green Top Sodium Heparin tube using standard aseptic technique.
Report Delivery
Maintain sample at 18-22°C and ship immediately. Do not refrigerate or freeze.
Timeline: Sample daily by 9 am; report same day.
Patient Instructions
About This Test
Who Should Get This Test
The test detects cytoplasmic IgM heavy chain expression by flow cytometry to identify clonal B-cell populations and to aid in diagnosis, prognosis, and monitoring of B-cell malignancies such as lymphoma, leukemia, and multiple myeloma. It also serves as a pre-B cell acute lymphoblastic leukemia prognostic and clonal restriction marker.
How to Prepare
- Collect 3 mL whole blood in Lavender Top EDTA tube
- Collect 3 mL whole blood in Green Top Sodium Heparin tube
- Alternatively collect 2 mL bone marrow in Green Top Sodium Heparin tube
- Ship immediately at 18-22°C; do not refrigerate or freeze
- Specify time, date and clinical details on test request form
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is useful when B-cell malignancy is suspected or when monitoring treatment response and clonal restriction in conditions such as lymphoma, leukemia, and multiple myeloma. It should be interpreted with clinical, morphologic, and other immunophenotypic findings."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Refrigerated or frozen sample
- Sample received after 24 hours at room temperature
- Insufficient sample volume
- Unlabeled or mislabeled specimen
Understanding Your Results
If the result indicates clonal restriction or if symptoms such as enlarged lymph nodes, fever, night sweats, unexplained weight loss, fatigue, bone pain, or abnormal bleeding persist, consult an oncologist or hematologist.
Limitations
- ⚠Flow cytometry requires viable cells and cannot replace histopathological, cytogenetic, or molecular studies
- ⚠Results must be correlated with morphology, clinical findings, and other immunophenotypic markers
Risks & Considerations
- ●Mild pain or bruising at venipuncture site
- ●Bone marrow collection may cause temporary discomfort
Interfering Factors
- ●Refrigerated or frozen sample
- ●Sample exposure to temperatures other than 18-22°C
- ●Delay in transport beyond 24 hours
- ●Insufficient sample volume
- ●Inadequate clinical details on test request form
Frequently Asked Questions
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