Immunohistochemistry Napsin-A Test
Short Name: Napsin-A IHC Test
Also known as: Napsin-A Immunohistochemistry, IHC Napsin-A Test
Immunohistochemistry Napsin-A Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block samples. Results in Reports are typically available within 5-7 days from sample receipt. Daily reports are sent by 6 PM for samples received that day.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of the Immunohistochemistry Napsin-A Test is to identify Napsin-A protein expression in tissue samples, which aids in the differential diagnosis of lung adenocarcinoma versus renal cell carcinoma. It confirms the origin of metastatic tumors and supports personalized cancer treatment strategies.
- Test Code
- 1100
- Price
- ₹3,500
- Sample Type
- Tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block
- Result Time
- Reports are typically available within 5-7 days from sample receipt. Daily reports are sent by 6 PM for samples received that day.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Ensure a biopsy has been performed and tissue sample is available. Provide all necessary clinical history and prior reports.
Method: Biopsy tissue submission
Laboratory Analysis
Biopsy tissue should be collected using standard aseptic techniques and placed in appropriate fixative immediately.
Report Delivery
Transport the sample to the laboratory at room temperature as per instructions. Monitor biopsy site for any complications.
Timeline: Reports are typically available within 5-7 days from sample receipt. Daily reports are sent by 6 PM for samples received that day.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Immunohistochemistry Napsin-A Test is to identify Napsin-A protein expression in tissue samples, which aids in the differential diagnosis of lung adenocarcinoma versus renal cell carcinoma. It confirms the origin of metastatic tumors and supports personalized cancer treatment strategies.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or as formalin fixed paraffin embedded block
- Ship at room temperature
- Provide a copy of the histopathology report
- Include site of biopsy and clinical history
- Ensure sample is properly labeled and documented
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"This test is crucial for accurate diagnosis and treatment planning in suspected lung or kidney cancers, helping to guide therapeutic decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample without proper fixation
- Inadequate tissue volume
- Missing clinical information or reports
- Sample contaminated or damaged during transport
Understanding Your Results
Positive Napsin-A staining
Suggestive of lung adenocarcinoma origin. Common in primary lung cancers and some metastatic cases.
Action: Consult oncologist for further staging and treatment planning.
Negative Napsin-A staining
May indicate renal cell carcinoma, other lung cancer types, or non-neoplastic conditions. Further testing recommended.
Action: Consider additional IHC markers or imaging studies for accurate diagnosis.
Consult a doctor if you experience symptoms like persistent cough, chest pain, hemoptysis, unexplained weight loss, or if you have a family history of cancer. Also, consult if test results are abnormal or inconclusive for proper follow-up.
Limitations
- ⚠Not a standalone diagnostic tool; must be correlated with clinical and histopathological data
- ⚠False positives or negatives can occur due to technical issues
- ⚠Limited to detection of Napsin-A; does not provide genetic mutation information
- ⚠Requires specialized laboratory equipment and expertise
Risks & Considerations
- ●Minimal risk from the test itself as it is performed on already collected tissue
- ●Biopsy-related risks include bleeding, infection, or discomfort at the biopsy site
- ●Rare chance of false results leading to misdiagnosis
Interfering Factors
- ●Improper tissue fixation or processing
- ●Inadequate sample size or quality
- ●Cross-reactivity with similar proteins
- ●Technical errors in staining protocol
Frequently Asked Questions
What is the Immunohistochemistry Napsin-A Test?
Why is this test done?
What sample is required for the test?
How much does the test cost at DNA Labs India?
Is home sample collection available?
How long does it take to get results?
What does a positive Napsin-A result mean?
Is fasting required before the test?
What are the risks of the test?
Can this test detect all types of lung cancer?
How should I prepare for the test?
What should I do after receiving the results?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.