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ITGA2B Gene Thrombocytopenia, neonatal alloimmune NGS Genetic Test

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ITGA2B Gene Thrombocytopenia, neonatal alloimmune NGS Genetic Test

Short Name: ITGA2B NGS Genetic Test

ITGA2B Gene Thrombocytopenia, neonatal alloimmune NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3-4 weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAll ages, with focus on neonates🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To identify mutations in the ITGA2B gene that cause neonatal alloimmune thrombocytopenia, facilitating accurate diagnosis, genetic counseling, and personalized treatment plans.

Test Code
2696
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3-4 weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Clinical history of the patient and a genetic counseling session to draw a pedigree chart of family members affected with ITGA2B gene thrombocytopenia.

Step 2

Laboratory Analysis

Your sample is analyzed using Next-Generation Sequencing (NGS) in our laboratory.

Step 3

Report Delivery

A certified pathologist reviews and signs your report. You receive it as a secure PDF via email and WhatsApp.

Timeline: 3-4 weeks

Patient Instructions

1
Before the Test:Provide detailed clinical history and undergo genetic counseling as part of pre-test preparation.
2
During the Test:Sample collection via blood draw or saliva, which is minimally invasive.
3
After the Test:Results are analyzed in the lab, and a report is generated with genetic findings.

About This Test

Who Should Get This Test

To identify mutations in the ITGA2B gene that cause neonatal alloimmune thrombocytopenia, facilitating accurate diagnosis, genetic counseling, and personalized treatment plans.

How to Prepare

  • For blood sample: Collect in EDTA tube via venipuncture.
  • For saliva sample: Use provided collection kit and follow instructions.
  • For FTA card: Apply one drop of blood and air-dry.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This test is crucial for diagnosing genetic causes of thrombocytopenia in neonates, aiding in early intervention and management to prevent bleeding complications."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card

Understanding Your Results

Results indicate the presence or absence of mutations in the ITGA2B gene. Positive results suggest a genetic basis for thrombocytopenia, while negative results may require further investigation.
📊

Positive for pathogenic variant

Confirms genetic cause of thrombocytopenia; genetic counseling and management recommended.

📊

Negative for pathogenic variant

No ITGA2B gene mutation detected; consider other diagnostic tests for thrombocytopenia.

📊

Variant of uncertain significance

Further testing or family studies may be needed for clarification.

⚠️ When to Consult a Doctor:

If experiencing unexplained bleeding, bruising, or if there is a family history of thrombocytopenia, consult a hematologist or genetic specialist for evaluation and possible testing.

Limitations

  • ⚠May not detect all genetic variants due to technical limitations
  • ⚠Results require interpretation by a genetic specialist
  • ⚠Does not rule out other causes of thrombocytopenia

Risks & Considerations

  • ●Minimal physical risks from sample collection (e.g., bruising at blood draw site)
  • ●Potential psychological impact of genetic results

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA quality
  • ●Recent blood transfusions may affect results

Frequently Asked Questions

What is ITGA2B gene thrombocytopenia?
It is a genetic blood disorder caused by mutations in the ITGA2B gene, leading to low platelet counts and bleeding complications, often in neonates.
What are the common symptoms of this condition?
Symptoms include easy bruising, nosebleeds, gum bleeding, blood in urine or stool, heavy menstrual bleeding, and prolonged bleeding after injuries.
How is the ITGA2B gene thrombocytopenia diagnosed?
Diagnosis involves physical exams, medical history, blood tests, bone marrow biopsy, and genetic testing like this NGS test.
What is the cost of the NGS Genetic Test in India?
The test costs INR 20000 at DNA Labs India, with possible discounts for online bookings.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection across many cities in India for this test.
How long does it take to get the test results?
Results are typically available within 3-4 weeks after sample collection.
What sample types are accepted for this test?
Blood, extracted DNA, or one drop of blood on an FTA card can be used.
Who should consider getting this genetic test?
Individuals with symptoms of thrombocytopenia, family history of the condition, or suspected neonatal alloimmune thrombocytopenia.
What does a positive test result mean?
A positive result indicates a mutation in the ITGA2B gene, confirming a genetic cause for thrombocytopenia, which may require specialized management.
Is genetic counseling required before the test?
Yes, a genetic counseling session is recommended to discuss implications, draw a family pedigree, and understand the test process.
Are there any risks associated with this test?
Risks are minimal, mainly related to sample collection (e.g., bruising), but psychological impacts of results should be considered.
How can I book the ITGA2B gene thrombocytopenia NGS test?
You can book online through DNA Labs India's website or contact them via phone or WhatsApp for assistance.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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